Abhisek Kar
Ph.D. Research Scholar
HYDERABAD
Summary
Dynamic professional with a career journey that began as a chemist and evolved into a seasoned chemical biologist. Possess a solid foundation in chemistry, including extensive experience in chemical synthesis, analysis, and laboratory techniques. Transitioned seamlessly into the realm of chemical biology, applying deep scientific knowledge to bridge the gap between chemistry and biology. Proficient in designing and conducting experiments to elucidate complex biological processes, utilizing interdisciplinary skills to make meaningful contributions to scientific research. Adept at fostering collaboration between scientists from diverse backgrounds. Eager to continue this transformative journey and contribute expertise as a chemical biologist.
Overview
2
2
years of professional experience
3
3
Languages
Work History
Research Associate
Tata Institute Of Fundamental Research - Hyderabad
HYDERABAD
07.2023 - Current
I am a researcher in Biochemistry at TIFR, Hyderabad, India, with a deep passion for bridging biology and chemistry. My current research focus is pioneering novel chemical protein synthesis techniques to unravel the molecular intricacies of protein function. I excel in diverse biochemical and biophysical methods, including manual and automated solid-phase peptide synthesis, reverse-phase HPLC for protein and peptide purification, surface plasmon resonance for molecular binding studies, LC-MS for molecular characterization, as well as CD, NMR, and fundamental protein crystallography. Committed to advancing knowledge at the biology-chemistry nexus.
Education
Ph.D. - Peptide Therapeutics, Protein Engineering
Tata Institute of Fundamental Research
Hyderabad 07.2023 - 07.2023
Skills
Lab operations
Accomplishments
Publications from academic journey:
[1] Efficient Chemical Protein Synthesis using Fmoc-Masked N-Terminal cysteine in Peptide Thioester Segments. Angewandte Chemie, International Edition. 2020, 59, 14796-14801. Kar A, Mannuthodikayil J, Singh S, Biswas A, Dubey P, Das A and Mandal K*
[2] Achieving Total Chemical Synthesis of the Enigmatic SARS-CoV-2 Spike Receptor-Binding Domain. Kar A, Jana M, Malik V, Sarkar A and Mandal K* (Submitted, June 2023)
[3] Benzimidazolinone-free peptide o-aminoanilides for chemical protein synthesis. Organic Letters. 2019, 21, 9040-9044. Mannuthodikayil J, Singh S, Biswas A, Kar A, Tabassum W, Vydyam P, Bhattacharyya, MK and Mandal K*
[4] Efficient refolding and functional characterization of PfAMA1(DI+DII) expressed in E. coli. Biochemistry and Biophysics Reports. 2021, 26, 100950. Biswas A, Raran-Kurussi S, Narayan A, Kar A, Mashurabad PC, Bhattacharyya MK and Mandal K*
[5] Solvent-assisted monomeric molecular structure of the phosphate diester and the synthesis of menthol-based phosphate diesters. J. Chem. Sci. 2019, 131, 1–11. Mandal D, Gupta V, Santra B, Chrysochos N, Bhoyare V W, Maiti A, Kar A, Suman, Guha A, Thakur P, Narayanan R S, Patil N T, Schulzke C, Chandrasekhar V, Jana A*
Honors & awards
Best work presentation award in the 8th Indian Peptide Symposium Issued by Indian Peptide Society · Mar 2021
Timeline
Research Associate
Tata Institute Of Fundamental Research - Hyderabad
07.2023 - Current
Ph.D. - Peptide Therapeutics, Protein Engineering
Tata Institute of Fundamental Research
07.2023 - 07.2023
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