Alderson Joshi C
Research Scientist
Tiruvallur,UP
Summary
Dynamic professional with extensive experience in biotechnology and a proven track record of leading teams to achieve project goals. Skilled in training junior staff, developing SOPs, and ensuring compliance with safety standards. Committed to driving innovation and quality in research initiatives.
Overview
5
5
Languages
1
1
Certification
14
14
years of professional experience
Work History
Research Scientist
Kothari Sugars And Chemicals Ltd
12.2024 - Current
- Utilized advanced analytical techniques to assess product performance and compliance with safety standards.
- Conducted experiments to analyze chemical compounds for product development and quality enhancement.
- Collaborated with cross-functional teams to design and implement research protocols.
- Documented research findings in detailed reports, ensuring accuracy and clarity for stakeholder review.
- Maintained laboratory equipment, ensuring operational readiness and adherence to safety regulations.
- Trained junior staff on laboratory procedures and best practices in research methodologies.
- Evaluated data trends to support strategic decisions in product innovation and process optimization.
- Prepared BMR, SOP, EOP, and IOP.
- Involved in product registration, filing applications in BioRRAP, filing CDSCO import licenses, pre-clinical studies, stability tests, and bioassays. I was also a member of internal IBSC meetings.
- Trained freshers in CIP, ESIP, and FSIP.
- Involved in the preparation of URS for a fully automated 200L fermentor to FAT until SAT.
- Involved in establishing a mammalian cell culture lab, from the qualification of the clean room, cell culture lab equipment like the microscope, incubator, and BSC-II, to commissioning.
Assistant Manager
Shilpa Biologicals Pvt Ltd
04.2024 - 12.2024
- Prepared SOP, EOP, and detailed project report on clone development.
- Trained the team of five scientists in transformation, DNA scale-up, linearization of plasmid, co-transfection of three plasmids with different selection markers in CHO-S cells to screen monoclonal clones using limiting dilution, and optimizing media for the best-expressing clone.
Associate Scientist
Aragen Lifesciences Pvt Ltd
12.2020 - 10.2023
- Led a team of 4 or more scientists in training, project initiation, planning, monitoring and controlling, and final project handoff to the client within the specified timeline.
- Cell line qualification, cell line revival, and seed raising for transfection.
- Developed 14 stable cell lines in HEK293A for drug targeting and bioassay, and transiently expressed more than 20 recombinant proteins for Novartis, Corteva, ONO Pharmaceuticals, Ducentis Biotherapeutics, and Seed Therapeutics.
- Developed Standard Operating Procedures (SOPs) to meet scientific research requirements.
- Handled cell lines like Hek 293A, Hek 293AD, Cap-T, Jurkat, THP-1, DU145, HCT116, SF9, High five and RAW 264.7 cells.
Associate Scientist
Syngene International Ltd
02.2016 - 12.2020
- Transient expression of protein in a mammalian cell line and stable cell line development.
- worked in CHO-K1,CHO-DG44, CHO-S, HEK-F, HEK293-6E and CHO-3E7
- Collaborated with cross-functional teams to ensure project timelines and deliverables were met.
Junior Research Fellow
Kalasalingam Academy of Research and Education
02.2014 - 08.2015
- Analyzed data sets using statistical software to derive meaningful insights for ongoing projects.
- Collaborated on experimental design, ensuring compliance with ethical standards and protocols.
- Conducted literature reviews to support research initiatives and inform project direction.
- Work in the funded project "Molecular Characterization of Mitochondrial Bka Channel in CBA/J Mouse Cochlear Hair Cell."
Scientist
Lablinks BioTech Pvt Ltd
12.2012 - 12.2013
- Media preparation, filter sterilization, and bioburden testing using soybean casein digest and fluid thioglycolate.
- Dulbecco’s saline, cold trypsin, and Trypan blue dye preparation for cell culture.
- Everyday observation and passaging of a 100% confluent cell line.
- Cell freezing mix preparation and freezing of cells in liquid nitrogen.
- Infection of the polio virus in Hep2C cells, virus propagation, virus concentrating using TFF, and virus titration (plaque assay and endpoint TCID50).
- Lactase production in a disposable bioreactor worked in the company's unique and innovative Torocell Bioreactor.
Education
MBA - Project Management
Manipal University
Jaipur, India 04.2001 -
Project Management Professional (PMP) - Project Management
Project Management Institute
united states of America 04.2001 -
M.Tech - Biotechnology
SRM University
Kattankulathur, India 04.2001 -
B.Tech - Biotechnology
Anna University
Tirupattur, India 04.2001 -
Skills
Laboratory techniques
Scientific writing
Documentation expertise
Research planning
Experiment design
Root-cause analysis
Experimental design
MS Excel
Project management
Problem-solving
Teamwork and collaboration
Excellent communication
Planning and scheduling
Accomplishments
- Team excellence award-certificate of appreciation for project pilot work for top Biopharma company -Hod Jul 2023
- Certificate for outstanding achiever award - Associate director Apr 2022
- Certificate of excellence-Kiran mazudar shaw, Chairperson of BIOCON,Jan 2019
- Spot Award - Jaya Shree, Head of the biology department, 2018.
Certification
PMP
Timeline
Research Scientist
Kothari Sugars And Chemicals Ltd
12.2024 - Current
Assistant Manager
Shilpa Biologicals Pvt Ltd
04.2024 - 12.2024
Associate Scientist
Aragen Lifesciences Pvt Ltd
12.2020 - 10.2023
Associate Scientist
Syngene International Ltd
02.2016 - 12.2020
Junior Research Fellow
Kalasalingam Academy of Research and Education
02.2014 - 08.2015
Scientist
Lablinks BioTech Pvt Ltd
12.2012 - 12.2013
MBA - Project Management
Manipal University
04.2001 -
Project Management Professional (PMP) - Project Management
Project Management Institute
04.2001 -
M.Tech - Biotechnology
SRM University
04.2001 -
B.Tech - Biotechnology
Anna University
04.2001 -