Alpana Kumar Gupta

Successful Principal Investigator with demonstrated expertise in chemical research with laboratory experimentation. Leads teams and manages projects with decisive, knowledgeable and forward-thinking approach.

Self-motivated and organized to work independently under minimal supervision.

Research Scientist with 20 years of experience of writing grant proposals, reports and collaborating with others to produce journal articles. Extensive knowledge of scientific data review, analysis, and publication processes with proficiency in English and Hindi.

Adept researcher, writer and editor, Expert at correcting sentence structure, grammar by rewriting, editing and proofreading.

• From cultivation to cancer: formation of N-nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications, Crit Rev Toxicol, 11/2023, Stanfill SB, Hecht SS, Joerger AC, González PJ, Maia LB, Rivas MG, Moura JJG, Gupta AK, Le Brun NE, Mehrotra R et al., 10.1080/10408444.2023.2264327, 38050998
• Oral Cancer Risk Assessment for Different Types of Smokeless Tobacco Products Sold Worldwide: A Review of Reviews and Meta-analyses, Cancer Prev Res (Phila), 11/2022, Alpana K Gupta, Mona Kanaan, Kamran Siddiqi, Dhirenra N Sinha, Ravi Mehrotra
• Increasing Use of Flavoured Tobacco Products Amongst Youth, Indian Journal of Tuberculosis (Elsevier), 11/2021, Alpana K Gupta, Ravi Mehrotra, 10.1016/j.ijtb.2021.07.020
• Safety Concerns for Tobacco-Free Products Containing Synthetic Nicotine, Nicotine & Tobacco Research, 04/2021, Alpana K Gupta, Ravi Mehrotra, 10.1093/ntr/ntab071
• Presence of High Level of Sugars, Humectants and their Toxic By-Products in Diverse Tobacco Products, Nicotine & Tobacco Research, 01/2021, Alpana K Gupta, Ravi Mehrotra, 10.1093/ntr/ntab010
• Tobacco use as a well-recognized cause of severe COVID-19 manifestations, Respiratory Medicine, 04/2021, Alpana K Gupta, Suzanne T Nethan, Ravi Mehrotra, 10.1016/j.rmed.2020.106233
• Alarmingly High Levels of Nicotine and Carcinogenic Nitrosamines in Smokeless Tobacco Products Sold Worldwide, Nicotine & Tobacco Research, Alpana K Gupta, Ravi Mehrotra, doi.org/10.1093/ntr/ntaa184
• Chemistry, metabolism and pharmacology of carcinogenic alkaloids present in areca nut and factors affecting their concentration, Regulatory Toxicology and Pharmacology, 2020, Alpana K Gupta, Sonam Tulsyan, Dhirendra N. Sinha, Ravi Mehrotra, 10.1016/j.yrtph.2019.104548
• Grassroots approach to control levels of carcinogenic nitrosamines, NNN and NNK in Smokeless tobacco products, Food and Chemical Toxicology, 2019, Alpana K Gupta, Sonam Tulsyan, Mausumi Bharadwaj, Ravi Mehrotra, 10.1016/j.fct.2018.12.01
• A Systematic Review on Cytotoxic and Anticancer Potential of N-Substituted Isatins as Novel Class of Compounds Useful in Multi-Drug Resistant Cancer Therapy: In-silico and in-vitro analysis, Topics in Current Chemistry, 2019, Alpana K Gupta, Sonam Tulsyan, Mausumi Bharadwaj, Ravi Mehrotra, 10.1007/s41061-019-0240-9
• Eco-friendly polyethylene glycol-400 as a rapid and efficient recyclable reaction medium for the synthesis of anti-cancer Isatin linked chalcones and their 3-hydroxy precursor, Journal of Heterocyclic Chemistry, 2018, Alpana K Gupta, Mausumi Bharadwaj, Ravi Mehrotra, 10.1002/jhet.3424
• Spiro-oxindoles as a promising class of small molecule inhibitors of p53-MDM2 interaction useful in targeted cancer therapy, Topics in Current Chemistry, 2017, Alpana K Gupta, Mausumi Bharadwaj, Anoop Kumar, Ravi Mehrotra, 10.1007/s41061-016-0089-0
• Skin cancer concerns in people of color: risk factors and prevention, Asian Pacific Journal of Cancer Prevention, 2016, Alpana K Gupta, Mausumi Bharadwaj, Ravi Mehrotra, 10.22034/APJCP.2016.17.12.5257
• Synthesis and evaluation of in-vitro antioxidant, cytotoxic and cell apoptotic activity of some new 5-substituted 2-oxindole derivative, Chemistry Central Journal, 2014, Alpana K Gupta, Rama S. Dubey, Saripella Srikrishna, and Jitendra K. Malik
• Application of modern electroanalytical techniques: Recent trend in pharmaceutical and drug analysis, International Journal of Pharmaceutical Sciences, 2013, Alpana K Gupta, Rama S. Dubey, Jitendra K. Malik
• Synthesis and in vitro antioxidant activity of new 3-substituted-2-oxindole derivatives, Indian Journal of Pharmaceutical Sciences, 2012, Alpana K Gupta, S. Kalpana, J.K. Malik
• Electrochemical reduction of 3-[5-phenyl pyrazol-3-ylimino] indol-2-ones at HMDE, Journal of Chemical Sciences, 2009, Alpana K Gupta and R. S. Sindal
• Voltammetric studies of 5-substituted isatins, Analytical Chemistry, 2008, Alpana K Gupta and R. S. Sindal
• Comparative voltammetric behaviour of isatin and some of its Schiff bases at a solid electrode, Journal of Indian Chemical Society, 2008, Alpana K Gupta and R. S. Sindal
• Cyclic voltammetric behaviour of isatin on HMDE in different conditions, Journal of Indian Chemical Society, 2007, Alpana K Gupta and R. S. Sindal
• Synthesis of some fluorine containing spiro(indole-dihydropyridine) derivatives, Indian Journal of Chemistry, 1996, Dandia, Alpana K Gupta, V. Sehgal and B. Rani
• Investigation of the reactions of some new fluorine containing 3-aroylmethylene indol-2-ones with urea and thiourea, Journal of Indian Chemical Society, 1995, Dandia and Alpana K Gupta
• Synthesis of 2-aryl-1H-imidazo [4,5-b] indoles, Indian Journal of Chemistry, 1994, Dandia and Alpana K Gupta
• Reaction of 3-(1,2,4-triazol-3-yl imino) indol-2-ones with thioacids: Synthesis of some novel sulfur containing spiro indole derivatives, Phosphorus, Sulfur, Silicon and Related Elements, 1994, Dandia and Alpana K. Gupta

• INDIA: SIKKIM CANCER NUMBERS SHOW IMPACT OF TOBACCO CONTROL, https://tobaccocontrol.bmj.com/content/30/1/4
• Even 10-year-old Indians are starting to use smokeless tobacco: 4 reasons behind it, https://theprint.in/opinion/even-10-year-old-indians-are-starting-to-use-smokeless-tobacco-4-reasons-behind-it/2007761/
• Areca nut isn't a harmless sweet supari, govt must regulate it like tobacco, https://theprint.in/opinion/areca-nut-isnt-a-harmless-sweet-supari-govt-must-regulate-it-like-tobacco/1947128/
• No gutkha, zarda or khaini is safe, but their risk of causing cancer can be reduced, https://hindi.theprint.in/opinion/no-gutkha-zarda-or-khaini-is-safe-but-their-risk-of-causing-cancer-can-be-reduced/662993/
• No gutkha, zarda or khaini is safe, but here's how their cancer-causing risk can be reduced, https://theprint.in/opinion/no-gutkha-zarda-or-khaini-is-safe-but-heres-how-their-cancer-causing-risk-can-be-reduced/1966957/

• Worked as Guest faculty for undergraduate classes (Chemistry) between 2005-2008
• Authored more than 25 articles as first author in various highly indexed medical, biomedical and chemical journals.
• Co-authored many research publications in international collaboration like University of York, Heslington, United Kingdom and Centers for Disease Control and Prevention, Atlanta, GA, USA
• Acted as reviewer for many scientific Journals like Nicotine and tobacco research (NTR), Tobacco induced disease(TID)
• Written many articles for the newspaper for increasing awareness about to tobacco and areca nut related cancer.
• Written grant proposals for NICPR and Healis institutes, Navi Mumbai.
• Done various online courses on "Smokeless Tobacco" organized by WHO FCTC-global knowledge hub on smokeless tobacco (GKH-SLT) at ICMR-NICPR in collaboration with Tobacco control Research Branch (TCRB) at National Cancer Institute (NCI), USA
• Attended various "National Tobacco Control Programs", organized by Ministry of Health and Family Welfare, GOI at ICMR-NICPR, Noida

• English, Professional Proficiency
• Hindi, Full Professional Proficiency

Public Health currently working in the area of tobacco-control in India, creating awareness about chemical toxicity of diverse Tobacco and Areca Nut containing Products.