Anupam Karmakar
Ewing
Summary
Scientist skilled in leading research projects and driving innovative solutions. Deep expertise in experimental design, data analysis, and scientific writing. Strong focus on collaborative efforts and achieving measurable results. Known for adaptability, critical thinking, and reliability in dynamic environments.
Overview
7
7
years of professional experience
Work History
Senior Scientist, Process Chemistry
TCG GreenChem Inc.
08.2023 - Current
- Developed safe, innovative, competitive, scalable and sustainable chemical processes for the synthesis of APIs.
- Route scouting through laboratory-scale experiments to determine suitable routes that can be taken for the process development.
- Maintained detailed records of all research activities in accordance with company policies and regulatory requirements, ensuring the accessibility and integrity of critical data.
- Work closely with analytical and crystallization team to achieve specifications set by ICH guidelines.
- Prepare RMC sheet for cost calculation.
- Work on various internal innovative projects for publication
Ph.D. Work
Temple University
08.2018 - 07.2021
- Research work done under the supervision of Dr. Rodrigo B. Andrade.
- Developed novel methodologies with N-sulfinyl imines inspired by complex natural products.
Ph.D. Work
Temple University
08.2021 - 07.2023
- Research work done under the supervision of Dr. Daniel K. Kim.
- Developed novel activation of 2-oxoacids via photoredox catalysis to access alpha-hydroxy-gamma-lactones, a prevalent motif in various natural products, active pharmaceutical and agrochemical ingredients.
Education
Ph.D. - Organic Chemistry
Temple University
Philadelphia, PA07.2023
M.Sc. - Chemistry
Indian Institute of Technology Kharagpur
06.2018
B.Sc. - Chemistry
The University of Burdwan
06.2016
Skills
- Research and experiments
- Data analytics
- Safety processes and procedures
- Experimental design
- Chemical synthesis
- Scientific writing
- Problem-solving
- Teamwork and collaboration
- Multitasking Abilities
- Excellent communication
- Critical thinking
- Planning and scheduling
- Technical skills: proficient in HPLC, GC, LCMS, NMR
Awards
Awarded departmental Daniel Swern Research Award for outstanding research in Ph.D.
Publications
- Anupam Karmakar*, Po-Cheng Yu, Femil J. Shajan, Vijay K. Chatare, William A. Sabbers, Eduardo M. Sproviero, and Rodrigo B. Andrade† Diastereoselective hydroxylation of N-tert-butanesulfinyl imines with 2-(phenylsulfonyl)-3-phenyloxaziridine (Davis Oxaziridine). Org. Lett. 2022, 24, 6548–6553.
- Po-Cheng Yu*, Anupam Karmakar, William Sabbers, Femil Shajan, Rodrigo B. Andrade†. Asymmetric Total Synthesis of (+)-Epiibogamine Enabled by Three Component Domino Michael/Michael/Mannich Annulation of N-Sulfinyl Metallosilylenamines Org. Lett. 2023, 25, 956–960.
- Rifat Nabi, Anupam Karmakar, Kimberly Jarquin, Kyle E. Brunner , Daniel K. Kim* Rapid Access to Trifluoromethyl Ketones by Photomediated Intramolecular Lactonization of α-Keto Acids.-Manuscript submitted.
- Yarra Venkatesh*, Joyjyoti Das, Amrita Chaudhuri, Anupam Karmakar, Tapas K. Maiti, and N.D. Pradeep Singh Light Triggered Uncaging of Hydrogen Sulfide (H2S) with Real-Time Monitoring. Chem Comm, 2018, 54, 3106-3109.
- Anupam Karmakar, Omkar Revu, Anji Chen, Jiezhen Li, Bo Qu, Chris Senanayake. A pre-acrylate handle as a very effective protecting group for thiol enabling synthesis of disulfide containing ADC linkers. -Manuscript under preparation.
Presentations
- Original Research Proposal for Elevation to Ph.D. Candidacy (July 2021); Title:- Merging Photoredox/Titanocene and Nickel Catalysis for Alkyl-Alkyl Fragment Coupling and Syntheses of Anti-Alzheimer's Natural Products - Temple University, Philadelphia, PA.
- Young Researchers Conference (YRC) (April 2019); Access to Complex Scaffolds of Bioactive Bis-Indole Alkaloids - Poster Session, Drexel University, Philadelphia, PA.
- Philadelphia Organic Chemists Club (POCC) (May 2022); Diastereoselective hydroxylation of N-tert-butanesulfinyl imines with 2-(phenylsulfonyl)-3-phenyloxaziridine (Davis Oxaziridine) - Poster Session, University of Pennsylvania, Philadelphia, PA.
Timeline
Senior Scientist, Process Chemistry
TCG GreenChem Inc.
08.2023 - Current
Ph.D. Work
Temple University
08.2021 - 07.2023
Ph.D. Work
Temple University
08.2018 - 07.2021
Ph.D. - Organic Chemistry
Temple University
M.Sc. - Chemistry
Indian Institute of Technology Kharagpur
B.Sc. - Chemistry
The University of Burdwan
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