Aravind Kumar Gurram

• Expertise in implementing novel manufacturing technologies such as Hot melt extrusion/twin screw granulation, Lipid based technologies and fluid bed processing techniques along with conventional granulation techniques.
• Highly proficient and expertise in designing strategies and process development of Sustained release dosage forms, taste masked powder for oral suspensions, Multiple Unit Particulate systems (MUPs) for delayed release application, fixed dose combinations (FDC), Emulsions, Microemulsions, Nanoparticles (polymeric and lipid based), Solid dispersions along with various conventional dosage forms like immediate release tablets and capsules.
• Designing experiments in Hot Melt Extrusion (HME) / twin screw granulation technique by using different types of excipients for its applications in pharmaceuticals and preparing case studies from the results.
• Establish processing conditions by conducting placebo experiments in HME for novel excipients (collaborating with specialized excipient manufacturers) and selecting a suitable plasticizers / other additive.
• Experienced to improve process efficiency from batch process to continuous manufacturing process (reducing number of unit operations) and is proven with majority of NSAIDs and anti-malarial molecules.
• Experienced in technology transfer of the process from laboratory scale to plant scale for different type of products and establishing suitable control strategies.
• Sound knowledge in preparing product development strategies, patent search reports, technical reports, and presentations for review on progress of projects.
• Experience in implementing Process Analytical Technology (PAT) in continuous manufacturing to ensure real time quality of the product.
• Experienced in implementing Process Analytical Technology (PAT) in continuous manufacturing to ensure real time quality of the product. r-100), Zeta Sizer (Nano ZS), Freeze dryer along with conventional instruments such as Granulating equipment’s, Rotary tablet press, Fluidized bed processor (GPCG 1.1).
• Have good experience on interpretation of raw data from analytical instruments such as DSC, XRD, SEM,TEM,TGA (Solid state characterization, Surface morphology of powders).
• Have wide knowledge and hands on experience in analytical and bioanalytical method development using UV spectrophotometer, HPLC and in designing bio relevant dissolution conditions.
• Hands on experience in pre-clinical studies. Lead a team of scientists and guided post graduate students on M. Pharmacy dissertation work during PhD Programme.

• Graduate Aptitude Test in Engineering (GATE) qualified with 93.03 Percentile in 2005 and received scholarship for post graduate studies.
• Received travel grant from Manipal College of Pharmaceutical Sciences to attend Indian Pharmaceutical Congress held in Ahmedabad, Gujarat during Dec 2009.
• Received travel grant from European Commission to attend Nanoformulations 2011, Singapore, May 2011.
• Served as Scientific Services Committee member for 62, 63, 64 Indian Pharmaceutical Congress (IPC) which was held at Manipal, Bangalore, Chennai respectively.
• Presented research work various National and International Pharmaceutical conferences.

• Evaluation of surfactant effect on self microemulsifying drug delivery system (SMEDDS) of Lercanidipine hydrochloride: Formulation and evaluation., Journal of Pharmaceutical Innovation, 10, 4, 374-387, 2015
• Role of components in the formation of self-microemulsifying drug delivery systems., Indian J Pharm Sci, 77, 3, 249-257, 2015
• Self-Microemulsifying drug delivery systems: An attractive strategy for enhanced therapeutic profile., International Scholarly Research Notices, 2014, 964051, 2014
• Formulation, characterization and in vivo evaluation of self-nanoemulsifying drug delivery system for oral delivery of Valsartan., Current Nanoscience, 10, 6, 263-270, 2014
• PLGA 50:50 nanoparticles of Paclitaxel: Development, in vitro anti-tumor activity in BT-549 cells and in vivo evaluation., Bull. Mater. Sci., 35, 319-326, 2012
• Sonophoresis- mediated permeation and retention of peptide dendrimers across human epidermis., Skin Res Technol., 18, 101-107, 2012
• Supercritical fluid technology: Concepts and pharmaceutical applications., PDA J Pharm Sci Technol., 65, 333-344, 2011
• Novel drug delivery systems: A microemulsion based approach., Pharma Times, 42, 4, 2010
• Novel Paclitaxel nanoparticles: Development, in vitro anti-tumor activity in BT-549 cells and in vivo evaluation., J Control Release, 148, 1, e119-21, 2010
• Applications of nanotechnology in health care: Perspectives and opportunities., Int J Green Nanotech: Biomed., 2, 2, B119-B133, 2010

• Microemulsions, Nanotechnology in Health Care, Shyam Prakashan, Jaipur, India, pp. 181-192
• Formulation of gliclazide encapsulated chitosan nanoparticles: In vitro and in vivo evaluation., NanoFormulation, Royal Society of Chemistry (RSC, UK.), conference proceedings of Nanoformulation 2011, Suntec, Singapore
• Preparation methods for nanoproducts, Exploring Nanotechnology in Health Care, Manipal University press, India

I hereby state that the above- mentioned information is true to the best of my knowledge and belief.

(G. Aravind Kumar)

01 January 2025