Bishnudeo Roy
Teaching and research
PUNE
Summary
Dedicated life-science/biotechnology researcher and teacher with sixteen years of research and six years of teaching experience, successfully contributing to immunology, molecular biology, cell biology, cancer biology, cancer immunology, animal tissue culture, immunological techniques, and the fundamentals of bioinformatics.
Overview
16
16
Years of research experience
6
6
Years of teaching experience
Work History
Assistant Professor
Symbiosis International (Deemed University)
10.2018 - Current
• Carried out curriculum revision, evaluation of course syllabi, and lesson plans for biotechnology subjects - immunology, molecular biology, cell biology, animal tissue culture, and immunological techniques courses.
• Delivered lectures and imparted training to students in above subjects.
• Guided students in designing, structuring, presenting, and implementing short- and long-term research projects.
• Organized journal clubs, guest lectures, extension and outreach activities, sports, and outdoor activities for students and colleagues.
• Established research agenda in vaccines (clinical research), environmental surveillance for viral pathogens, impact of biomolecules on immune response, cancer immunotherapy, human commensal-derived anti-cancer metabolites, inflammatory responses in diabetes, phototherapy, and other fields to publish in peer-reviewed journals.
• Secured external funding for research projects by writing competitive grant proposals and establishing connections with potential sponsors.
• Demonstrated strong organizational and time management skills while managing multiple projects.
• Maintained up-to-date knowledge of subject matter by attending conferences, workshops, and webinars relevant to the field of study.
• Contributed to departmental goals by serving on various committees focused on enhancing research, collaboration, entrepreneurship, consultancy, extension, and outreach activities complying with accreditation requirements.
• Strengthened relationships with colleagues by participating in collaborative projects and research endeavors.
• Established strong partnerships with other institutions for collaborative research projects
• Reviewed research articles as an invited reviewer for the international peer reviewed journals.
Researcher/Postdoc
Oslo University Hospital, Rikshospitalet
01.2014 - 04.2017
• Conducted research in the field of Immunology – an autoimmune disease: celiac disease and human gut health
• Worked on a European Research Council funded project focused on inflammatory bowel condition.
• Published high-impact articles in peer-reviewed journals, enhancing the reputation of the organization.
• Improvised the method for single cell high throughput sequencing of antibody genes and immunoglobulin profiling.
• I worked as a member of an integrated project team in highly collaborative work environment.
• Analyzed single cell next generation sequencing data into well-organized formats and transformed into figures.
• Collaborated with interdisciplinary teams to conduct comprehensive studies and generate valuable insights.
• Maintained detailed records of experimental procedures, observations, and results for accurate reporting and replication purposes.
• Synthesized large volumes of information, identifying key trends and patterns relevant to research objectives.
• Applied ethical considerations throughout all stages of the research process, safeguarding participant welfare and data integrity.
• Conducted thorough literature reviews to identify gaps in knowledge and inform future research directions.
• Presented research findings at national and international conferences, raising the profile of the institution.
• Worked effectively to meet the deadlines in fast-paced environments.
Research Scientist/Postdoc
Helmholtz Centre for Infection Research
6 2007 - 12.2013
• Advanced scientific understanding within the field of mucosal immunity, host-microbe interaction, and gut health by publishing impactful peer-reviewed articles.
• Utilized expertise in immunology, molecular biology, and animal experimentation to help address the research questions.
• Conducted document review, organization, and quality control of data acquisition to draw relevant conclusions and direct research activities.
• Enhanced research efficiency by optimizing experimental designs and protocols.
• Wrote research papers, reports, reviews, and summaries regarding the methods to induce antibody production by B cell subsets.
• Applied theories and methods of life sciences to interpret and perform analyses of experimental results.
• Presented research findings at international conferences, increasing visibility and recognition within the field.
• Evaluated new technologies for potential integration into existing research processes, driving continuous improvement efforts.
• Reviewed technical and professional publications and journals to stay current on recent literature and make more strategic research decisions.
• Worked flexible hours across night, weekend, and holiday shifts.
• Demonstrated a high level of initiative and creativity while tackling difficult tasks.
• Skilled at working independently and collaboratively in a team environment.
Education
Ph.D. - Biotechnology, Immunology
01.2004 - 06.2007
Master of Science - Biotechnology
07.2001 - 06.2003
Bachelor of Science - Chemistry
08.1998 - 06.2001
Skills
Academic research and publishing - immunology, molecular biology, cancer, diabetes
undefinedTimeline
Assistant Professor - Symbiosis International (Deemed University)
10.2018 - Current
Researcher/Postdoc - Oslo University Hospital, Rikshospitalet
01.2014 - 04.2017
Hannover Medical School - Ph.D., Biotechnology, Immunology
01.2004 - 06.2007
Madurai Kamaraj University - Master of Science, Biotechnology
07.2001 - 06.2003
Banaras Hindu University - Bachelor of Science, Chemistry
08.1998 - 06.2001
Research Scientist/Postdoc - Helmholtz Centre for Infection Research
6 2007 - 12.2013
Professional Recognition Award Prize Certificate Fellowship Received
- Postdoctoral fellowship, Oslo University Hospital, Oslo, Norway, 2014
- Postdoctoral fellowship, Hannover medical school, Hannover, Germany, 2007
- PhD fellowship, Hannover medical school, Hannover, Germany, 2003
- CSIR JRF, Council for Scientific and Industrial Research (CSIR), India, 2003
- Qualified for GATE (Graduate Aptitude Test in Engineering), Ministry of Human Resources Development (MHRD), 2003
- Department of Biotechnology (DBT) studentship, Department of Biotechnology, India, 2001
Administrative Responsibilities
- Dec 2022 to present - Faculty-in-charge, purchase (research equipment and consumables) committee
- Oct 2020 to present - Member, Institutional Animal Ethics Committee
- June 2020 to present - Member secretary, Institute Research Committee (IRC)
- Nov 2019 to present - Member secretary, Academic Integrity Committee (AIC)
- Jan 2019 to present - Faculty-in-charge, (Criteria III) National Assessment and Accreditation Council (NAAC)
- Jan 2019 to present - Member, Quality Improvement Committee (QIC)
Current Designation
Assistant Professor
Current Affiliation
Symbiosis School of Biological Sciences, Symbiosis International (Deemed University), Pune, Maharashtra, India
Personal Information
- Date of Birth: 08/04/78
- Gender: Male
Symbiosis School of Biological Sciences, Symbiosis International (Deemed University), Pune, Maharashtra, India
Research
Research area:
Immunology (Gut immunity, Autoimmunity, Immunomodulation, High throughput single cell sequencing, Cancer immunology), Biotechnology, Molecular Biology
Publications:
1. Asokan MS, Joan RF, Babji S, Dayma G, Nadukkandy P, Subrahmanyam V, Pandey A, Malagi G, Arya P, Mahajan V, Bhavikatti J, Pawar K, Thorat A, Shah P, Goud RB, Roy B, ...... Mayor S. Immunogenicity of SARS-CoV-2 vaccines BBV152 (COVAXIN) and ChAdOx1 nCoV-19 (COVISHIELD) in seronegative and seropositive individuals in India: a multicentre, nonrandomised observational study. Lancet Reg Health Southeast Asia. 2024 Feb 27;22:100361. doi: 10.1016/j.lansea.2024.100361.
2. Zambre S, Bangar N, Mistry A, Katarmal P, Khan MS, Ahmed I, Tupe R, Roy B. Aldosterone, Methylglyoxal, and Glycated Albumin Interaction with Macrophage Cells Affects Their Viability, Activation, and Differentiation. ACS Omega. 2024 Feb 27;9(10):11848-11859. doi: 10.1021/acsomega.3c09420.
3. Sisodiya S, Kasherwal V, Khan A, Roy B, Goel A, Kumar S, Arif N, Tanwar P, Hussain S. Liquid Biopsies: Emerging role and clinical applications in solid tumours. Transl Oncol. 2023 Sep;35:101716. doi: 10.1016/j.tranon.2023.101716.
4. Iversen R, Roy B, Stamnaes J, Høydahl LS, Hnida K, Neumann RS, Korponay-Szabó IR, Lundin KEA, Sollid LM. Efficient T cell-B cell collaboration guides autoantibody epitope bias and onset of celiac disease. Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):15134-15139. doi: 10.1073/pnas.1901561116.
5. Brennecke AM, Düber S, Roy B, Thomsen I, Garbe AI, Klawonn F, Pabst O, Kretschmer K, Weiss S. Induced B Cell Development in Adult Mice. Front Immunol. 2018 Oct 31;9:2483. doi: 10.3389/fimmu.2018.02483.
6. Blume J, Ziętara N, Witzlau K, Liu Y, Sanchez OO, Puchałka J, Winter SJ, Kunze-Schumacher H, Saran N, Düber S, Roy B, Weiss S, Klein C, Wurst W, Łyszkiewicz M, Krueger A. miR-191 modulates B-cell development and targets transcription factors E2A, Foxp1, and Egr1. Eur J Immunol. 2019 Jan;49(1):121-132. doi: 10.1002/eji.201847660.
7. Roy B, Neumann RS, Snir O, Iversen R, Sandve GK, Lundin KEA, Sollid LM. High-Throughput Single-Cell Analysis of B Cell Receptor Usage among Autoantigen-Specific Plasma Cells in Celiac Disease. J Immunol. 2017 Jul 15;199(2):782-791. doi: 10.4049/jimmunol.1700169.
8. Suwandi A, Bargen I, Roy B, Pils MC, Krey M, Zur Lage S, Basler T, Rohde M, Falk CS, Hornef MW, Goethe R, Weiss S. Experimental colitis is exacerbated by concomitant infection with Mycobacterium avium ssp. paratuberculosis. Inflamm Bowel Dis. 2014 Nov;20(11):1962-71. doi: 10.1097/MIB.0000000000000157.
9. Roy B, Brennecke AM, Agarwal S, Krey M, Düber S, Weiss S. An intrinsic propensity of murine peritoneal B1b cells to switch to IgA in presence of TGF-β and retinoic acid. PLoS One. 2013 Dec 6;8(12):e82121. doi: 10.1371/journal.pone.0082121.
10. Roy B, Agarwal S, Brennecke AM, Krey M, Pabst O, Düber S, Weiss S. B-1-cell subpopulations contribute differently to gut immunity. Eur J Immunol. 2013 Aug;43(8):2023-32. doi: 10.1002/eji.201243070.
11. Düber S, Hafner M, Krey M, Lienenklaus S, Roy B, Hobeika E, Reth M, Buch T, Waisman A, Kretschmer K, Weiss S. Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells. Blood. 2009 Dec 3;114(24):4960-7. doi: 10.1182/blood-2009-04-218156.
12. Roy B, Shukla S, Łyszkiewicz M, Krey M, Viegas N, Düber S, Weiss S. Somatic hypermutation in peritoneal B1b cells. Mol Immunol. 2009 May;46(8-9):1613-9. doi: 10.1016/j.molimm.2009.02.026.
13. Roy B, Shukla S, Stoermann B, Kremmer E, Düber S, Weiss S. Loss of lambda2(315) transgene copy numbers influences the development of B1 cells. Mol Immunol. 2009 Apr;46(7):1542-50. doi: 10.1016/j.molimm.2008.12.024.
Projects
1. Nov 2022 to Oct 2024: Development of novel anti-ageing phytotherapy for collective inhibition of glycation, amyloid formation and inflammation (INR 10 Lakhs, funded by Symbiosis Centre for Research and Innovation, SIU, Pune).
2. Apr 2023 to Jan 2024: Qualitative and quantitative evaluation of SARS-CoV-2, Dengue, Chikungunya, Influenza, and Respiratory Syncytial Virus (RSV) in wastewater from the Pune Region of Maharashtra, India (INR 58.50 Lakhs, funded by Rockefeller Foundation, USA through Pune Knowledge Cluster Foundation, Pune, India).
3. Sep 2021 to Mar 2023: Study on long-term immunogenicity of COVID-19 vaccines in vaccine-naïve seronegative and seropositive participants (INR 89.52 Lakhs, funded by Hindustan Unilever Limited (HUL) and Unilever India Pvt. Ltd. (UIPL) through Pune Knowledge Cluster Foundation, Pune, India).
4. Oct 2021 to Mar 2023: Environmental surveillance of SARS-CoV-2 in drainage water of Pune region of Maharashtra, India (INR 18.00 Lakhs, funded by Rockefeller Foundation, USA through Pune Knowledge Cluster Foundation, Pune, India).
5. Feb 2021 to Feb 2023: Assessment of SARS-Coronavirus-2 load in river water in Pune region of Maharashtra (INR 10.00 Lakhs funded by Symbiosis Centre for Research and Innovation, SIU, Pune, India)
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