Dhivyaa Anandan
Hyderabad
Summary
Accomplished Research Scientist specializing in biotechnology and bone tissue engineering. Expertise in scaffold and microfluidic device fabrication, with a focus on developing microchip-based cardiac and tumor models for drug screening. Proficient in molecular biology techniques, fluorescent methods, and cell-based assays.
Overview
16
16
years of professional experience
Work History
Research Scientist
Global Medical Education and Research Foundation
Hyderabad
07.2025 - Current
- Executed translational biomedical research projects, resulting in innovative solutions for clinical applications.
- Developed and optimized advanced in vitro models, enhancing drug testing accuracy and relevance.
- Interfaced with clinicians and industry representatives to ensure alignment of research outcomes with practical applications.
- Contributed to grant writing and scientific documentation for collaborative initiatives.
- Reviewed and evaluated scientific literature relevant to ongoing research projects.
- Mentored research trainees and coordinated laboratory workflows, fostering skill development and operational effectiveness.
- Collaborated with multidisciplinary teams on innovative healthcare education projects.
- Participated in conferences and seminars related to research science topics.
Junior and Senior Research Fellow
Vellore Institute of Technology
Vellore
10.2021 - 05.2024
- Collaborated with Christian Medical College and Hospital Vellore and Centre for Biomaterials Cellular and Molecular Theranostics to acquire patient tumor samples.
- Coordinated brainstorming sessions with orthopedic surgeons to investigate in vivo behavior of giant cell tumor of bone and create an in vitro model.
- Developed three-dimensional in vitro model of giant cell tumor of bone for drug screening purposes.
- Enhanced structural complexity and functionality of in vitro giant cell tumor of bone model.
- Exposed in vitro giant cell tumor of bone model to zoledronic acid, a common treatment for GCTB.
- Published findings in peer-reviewed journals to contribute to academic knowledge base.
- Acquired knowledge in mechanical characterization and applications of qualitative and quantitative polymerase chain reactions, Western blot analysis, immunohistochemistry, and immunocytochemistry.
- Acquired skills in operating and maintaining Olympus FV3000 confocal microscope and EVOS M5000 fluorescent microscope to support advanced imaging research.
- Attended demonstration of nano-lithography techniques for developing nanosized structures in tissue engineering.
Teaching and Research Assistant (TRA)
Vellore Institute of Technology
Vellore
10.2016 - 09.2019
- Led the tissue engineering lab at the Centre for Biomaterials Cellular and Molecular Theranostics (CBCMT) from 2016 to 2020.
- Trained undergraduate and postgraduate students in laboratory techniques, fostering skill development in biomaterial research.
- Developed scaffold composition systems with various crosslinkers through freeze-drying, advancing bone tissue engineering capabilities.
- Conducted comprehensive analyses to evaluate biomaterial properties for in vitro tumor modeling and tissue engineering.
- Synthesized hydroxyapatite via novel Schiff base method, enhancing biomaterial application potential.
Scientific Analyst
Molecular Connections
Chennai
04.2015 - 09.2015
- Prepared abstracts for scientific patents from regions including US, Europe, China, Korea, Turkey, and World Intellectual Property Organization.
- Categorized patent claims into independent and dependent categories, highlighting main independent claim as novelty.
- Described other independent claims in detailed description section and dependent claims in technology focus section.
- Assessed uses and advantages of novelty in patents, enhancing understanding of its application.
- Detailed mechanisms of action and administration under activity mechanism section.
- Presented examples and biological data to substantiate patent claims, reinforcing validity.
- Assigned titles for abstracts to reflect core innovations.
Research Assistant
SASTRA University
Thanjavur
10.2010 - 05.2012
- Conducted experiments on nanofluids in custom test rig to analyze pressure drop and pipe wall effects, informing system design and optimization.
- Prepared nanofluids using ultrasonicator and characterized properties with UV-Vis spectrophotometer, viscometer, thermal conductivity meter, and Zetasizer to support research objectives.
- Synthesized zinc oxide, copper oxide, and iron oxide nanoparticles for bioreactor coolant applications, contributing to material development.
Research Intern
Pasteur Institute of India (PIIC)
Coonoor
12.2009 - 02.2010
- Conducted experimental studies to adapt Vero cells to serum-free media, enhancing conditions for vaccine development.
- Streamlined downstream purification processes through serum-free adaptation of Vero cells, improving overall workflow efficiency.
- Oversaw handling and maintenance of Vero cell lines, ensuring viability for antirabies vaccine production.
Education
Doctor of Philosophy - Development of in vitro Tissue Engineered Model for Giant Cell Tumour of Long Bones
Vellore Institute of Technology (VIT)
Vellore, India08-2025
Post Graduate Diploma - Fermentation and Bioprocess Engineering
Probiosys
Bengaluru, India01-2013
Master of Technology - Medical Nanotechnology
SASTRA University
Thanjavur, India06-2012
Bachelor of Technology - Biotechnology
St. Joseph's College of Engineering
Chennai, India08-2010
Skills
- Molecular Biology Techniques - ELISA, PCR, Western Blot Analysis, Immunohistochemistry
- Cell culture techniques
- Primary tumour culture and 3D tumour modelling
- Biofabrication techniques such as Electrospinning and Freeze-drying
- Nanoparticle synthesis and characterization
- Fluorescence and Confocal Microscopy
Languages
- English
- Tamil
- Hindi
- Telugu
Publications And Patents
- Aarohi Shailesh Ranadive, Manisha Sonthalia, Dhivyaa Anandan, Amit Kumar Jaiswal, 2024 (filed), "METHOD FOR A STABLE HYDROGEL COMPOSITE TO IMPROVE THE PERFORMANCE IN BIOMEDICAL APPLICATIONS", 202441092486.
- Anandan, D., Mary Stella, S., Arunai Nambiraj, N., Vijayalakshmi, U., Jaiswal, A.K., 2018. Development of mechanically compliant 3D composite scaffolds for bone tissue engineering applications. J Biomed Mater Res A 106, 3267–3274.
- Anandan, D., Jaiswal, A.K., 2018. Synthesis and characterization of human bone-like hydroxyapatite using Schiff ’s base. Ceram Int 44, 9401–9407.
- Anandan, D., Madhumathi, G., Nambiraj, N.A., Jaiswal, A.K., 2019. Gum based 3D composite scaffolds for bone tissue engineering applications. Carbohydr Polym 214, 62–70.
- Anandan, D., Kumar, A., Jeyakkani, M.N., Inja, D.B., Jaiswal, A.K., 2023. Investigation of Giant Cell Tumor of Bone and Tissue Engineering Approaches for the Treatment of Giant Cell Tumor of Bone. ACS Appl Bio Mater, 6 (10), 3946-3958.
- Anandan, D., Jaiswal, A.K., 2023. Synthesis methods of hydroxyapatite and biomedical applications: an updated review. Journal of the Australian Ceramic Society, 60, 663-679.
- Anandan, D., Kumar, A., Jaiswal, A.K., 2023. Comparative study of hydroxyapatite synthesized using Schiff base and wet chemical precipitation methods. J Mech Behav Biomed Mater 148, 106200.
Awards And Technical Activities
- Best Poster Presentation Award, Society of Biomaterials & Artificially Organs (SBAOI), 2018
- Travel Grant (ITS), Science and Engineering Research Board (SERB), 2019
- Travel Grant, Centre for Co-operation in Science & Technology among developing societies (CCSTDS), 2019
Timeline
Research Scientist
Global Medical Education and Research Foundation
07.2025 - Current
Junior and Senior Research Fellow
Vellore Institute of Technology
10.2021 - 05.2024
Teaching and Research Assistant (TRA)
Vellore Institute of Technology
10.2016 - 09.2019
Scientific Analyst
Molecular Connections
04.2015 - 09.2015
Research Assistant
SASTRA University
10.2010 - 05.2012
Research Intern
Pasteur Institute of India (PIIC)
12.2009 - 02.2010
Doctor of Philosophy - Development of in vitro Tissue Engineered Model for Giant Cell Tumour of Long Bones
Vellore Institute of Technology (VIT)
Post Graduate Diploma - Fermentation and Bioprocess Engineering
Probiosys
Master of Technology - Medical Nanotechnology
SASTRA University
Bachelor of Technology - Biotechnology
St. Joseph's College of Engineering