Dr. ANTONY GEORGE FRANCIS THOTTIAN

Experienced Medical Oncology with good track record in Academics and Research, looking forward to hone skills in Phase 1 Clinical trials

• ESMO Certification Medical Oncology (2021)
• MRCP Speciality Certificate Examination – Medical Oncology (2021)
• Doctorate of National Board – Medical Oncology (2021)
• FRCR Clinical Oncology (2023)

• Member of Association of Radiologists of India (AROI)
• Member of European Society of Medical Oncology (ESMO)
• Fellow of Royal College of Radiologists, UK (RCR)
• Member of American Society of Clinical Oncology (ASCO)
• Member of Association Of Medical and Pediatric Oncologists of Kerala (AMPOK)

GRANTS

• Recipient of KVPY Scholarship from Department of Science and Technology, Government of India (2010)

• Council of Scientific and Industrial Research Travel Grant (2019)

2017 – 2022

• In-vitro Drug Sensitivity Testing of Lung Cancer Specimens for Response Prediction and Personalized Approach to Treatment of Lung Cancer

Guide – Dr Govind Babu, Ex-Professor and HOD, Department of Medical Oncology, Kidwai Cancer Institute

• Correlation of Serum Albumin and CRP Levels with Chemotherapy Toxicity in Patients of Metastatic Lung Cancer

Guide – Dr Lokesh KN, Associate Professor, Department of Medical Oncology, Kidwai Cancer Institute

• Evaluation of Safety and Efficacy of Minocycline combined with Tyrosine Kinase Inhibitors in Patients of EGFR mutated metastatic lung cancer

Guide – Dr Lokanatha D, Professor, Department of Medical Oncology, Kidwai Cancer Institute

• Ex vivo expansion and characterization of circulating non-small cell lung cancer cells for individualized drug susceptibility testing

Guide – Dr Govind Babu, Ex-Professor and HOD, Department of Medical Oncology, Kidwai Cancer Institute and Dr Prashanth, Faculty Scientist, Institute of Bioinformatics, Bangalore

2014 – 2016

• Patterns of Care in Carcinoma Oesophagus: Experience from Tertiary Care Centre in India

Guide – Dr Sushmita Pathy, Professor, Radiation Oncology, AIIMS-New Delhi. MD Thesis - Accepted February 2017.

2009 – 2012 – KVPY Research Fellow (Department of Science and Technology, Government of India)

• Mutational Analysis of CYP1B1 gene in patients of Congenital Glaucoma

Guide – Dr Rima Dada, Professor, Lab for Molecular Reproduction and Genetics, Department of Anatomy, AIIMS - New Delhi

• Molecular Epidemiology of Neisseria Meningitidis isolated from cases of invasive meningitis in Delhi Guide - Dr B. K Das, Professor, Department of Microbiology, AIIMS – New Delhi

• Peer Reviewed Journal Articles

Balakrishnan, A., Thottian, A.G.F., Govind Babu, K. et al. Drug susceptibility testing of circulating lung cancer cells for personalized treatment. Med Oncol 40, 1 (2023). https://doi.org/10.1007/s12032-022-01860-3

Rudresha, A.H., Hassan, S.A., Sreevalli, A. Thottian A.G.F. et al. Pre-phase strategy to mitigate first cycle effect in diffuse large B cell lymphoma. J Egypt Natl Canc Inst 34, 20 (2022). https://doi.org/10.1186/s43046-022-00116-5

Jose JV, Nair SR, Kayakkal S, Thottian AGF, Rasak AMM. Hepatocellular Carcinoma With a Floating Right Atrial Thrombus and Rupture of the Primary Lesion Causing Right-Sided Hemothorax. Indian Journal of Clinical Medicine. 2021;11(1-2):41-43. doi:10.1177/26339447221095344

Lokanatha D, Hassan SA, Jacob LA, Suresh Babu MC, Lokesh KN, Rudresha AH, Thottian AGF et al. Socioeconomic and administrative factors associated with treatment delay of oesophageal and gastric carcinoma: Prospective study from a tertiary care centre in a developing country. Cancer Epidemiol. 2020 Aug 1; 67:101770.

Babu MCS, Sreevalli A, Thottian AGF, Suma MN, Lokanatha D, Jacob LA, et al. Ewing’s sarcoma of the vulva: An

uncommon tumour in an uncommon site. Indian J Med Paediatr Oncol. 2020 May 1;41(3):397.

Babu MCS, Hassan SA, Premalata CS, Lokanatha D, Jacob LA, Lokesh NK, Thottian AGF et al. Rare case of isolated dural marginal zone lymphoma. Indian J Med Paediatr Oncol. 2020 Jan 1;41(1):61.

Rajeev LK, Thottian AG, Amirtham U, Lokanatha D, Jacob LA, Babu MC. et al. Primary mucinous carcinomas of the lung: Clinical characteristics and treatment outcomes. Lung India 2020; XX: XX-XX. (Accepted for publication; doi: 10.4103/lungindia.lungindia_52_20.

Suresh Babu, M.C., Thottian, A.G., Lokanatha, D. et al. Follicular lymphoma transforming to DLBCL and reverting back to follicular lymphoma at relapse—a case report. J Egypt Natl Canc Inst 32, 22 (2020).

Babu MCS, Thottian AF, Sai RK, Premalata CS, Lokanatha D, Jacob LA, et al. Hodgkin’s lymphoma of the stomach:

A rare entity. Indian J Med Paediatr Oncol. 2019 Jul 1;40(3):427.

Thottian AGF, Babu GK, Dasappa L, Jacob LA, Babu SM, Lokesh KN, et al. Evaluation of safety and efficacy of minocycline combined with tyrosine kinase inhibitors in patients of EGFR mutated metastatic lung cancer. Ann Oncol. 2019 Apr 1;30: ii76.

Francis Thottian AG, Gandhi AK, Ramateke PP, Gogia A. Acinic cell carcinoma of parotid gland with cavernous sinus metastasis: A case report. J Can Res Ther 2018; 14;1428-30.

Surviving Triple Trouble: Synchronous breast and cervical cancer, HIV Infection and Myocardial Infarction.

Thottian AG, Mallick S, Venkatesulu BP, Kumar R, KP Haresh, Gupta et al. Breast J, Nov 2016 25.

Thottian AGF, Pathy S, Gandhi AK, Malik P, Nambirajan A. Coughing up - Small cell carcinoma lung with gingival metastasis. J Egypt Natl Cancer Inst. 2016 Oct 18.

Thottian AGF, Benson R, Kashyap S, Haresh KP, Gupta S, Sharma D, et al. Orbital medulloepithelioma in an adult patient: Radiation-induced second neoplasia? Orbit. 2016 Aug 12;0(0):1–4.

Pathy S, Francis AG, Roy S. Comments onNeoadjuvant Chemo-radiation with IMRT in Resectable and Borderline Resectable Pancreatic Cancer. Asian Pac J Cancer Prev APJCP. 2015;16(13):5585.

• Abstracts

Thottian AGF, Babu GK, Dasappa L, Jacob LA, Babu SM, Lokesh KN, et al. Evaluation of safety and efficacy of minocycline combined with tyrosine kinase inhibitors in patients of EGFR mutated metastatic lung cancer. Ann Oncol. 2019 Apr 1;30: ii76.

Goyal S, Rudresha A, Lokanatha D, Jacob LA, Mc SB, Lokesh K, Rudresha AH, Rajeev LK, Saldanha S, Thottian AGF. A prospective study to assess response to neoadjuvant hormonal therapy in postmenopausal women with hormone-receptor positive breast cancer at a regional cancer centre in South India. Ann Oncol. 2019 Nov 1;30: ix12.

• Poster Presentations

A.G.F. Thottian, G.K. Babu, L. Dasappa, L.A. Jacob, S.M. Babu, K.N. Lokesh, A.H. Rudresha, S. Saldanha, G. Gv, R. Lk. Evaluation of Safety and Efficacy of Minocycline combined with Tyrosine Kinase Inhibitors in Patients of EGFR mutated Metastatic Lung Cancer. Abstract – Trial in Progress, Poster presented at European Lung Cancer Congress 2109, Geneva, Switzerland, April 2019.

A.G.F. Thottian, G.K. Babu, L. Dasappa, L.A. Jacob, S.M. Babu, K.N. Lokesh, A.H. Rudresha, L.K. Rajeev1 S. Saldanha, G. Gv. Primary Mucinous Carcinomas of the Lung: Clinical Characteristics and Treatment Outcomes. Abstract – Miscellaneous, Poster presented at European Lung Cancer Congress 2019, Geneva Switzerland, April 2019.

A.G.F. Thottian, G.K. Babu, L. Dasappa, L.A. Jacob, S.M. Babu, K.N. Lokesh, A.H. Rudresha, L.K. Rajeev1 S. Saldanha, G. Gv. Adult Burkitt’s Lymphoma: Institutional Experience from a South Indian Tertiary Cancer Hospital. Poster Presented at Lymphocon 2019, Bangalore, India. January 2019.

A.G.F. Thottian, L. Dasappa, L.A. Jacob, S.M. Babu, K.N. Lokesh, A.H. Rudresha, L.K. Rajeev1 S. Saldanha. Spatial and Temporal trends in Acute Promyelocytic Leukaemia diagnosed at a Tertiary Cancer Centre in South India. Poster Presented at 1st Annual Meeting of Haematology Cancer Consortium 2019, Kochi, India. August 2019.

A.G. Thottian, B.P. Venkatesulu, S. Chaliyadan, G.K. Rath. Primary Squamous Cell Carcinoma of the Stomach (PSCCS) – A Systematic Review and Meta•analysis. Poster presented at ESMO ASIA 2016, Singapore. December 2016.