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Experienced and licensed dentist with a strong background in patient interaction and care. Skilled in diagnosing, treating, and counseling patients, with expertise in managing dental administrative tasks such as scheduling, telehealth coordination, and electronic health records (EHR) management. Adept in clear communication, patient follow-ups, and improving patient outcomes through data-driven decisions.

Accomplished medical professional with over five years of experience in patient care across various specialties, currently engaged in Internal Medicine rotation. Proficient in assessing, diagnosing, and stabilizing acutely ill patients, with a strong track record in high-pressure clinical environments. Expertise includes Acute Medicine, Respiratory Medicine, Geriatrics, and Palliative Care, with significant contributions during the COVID-19 pandemic and mentorship of junior staff. Dedicated to patient-centered care through effective collaboration within multidisciplinary teams.

  AFFILIATIONS:   SITC, ESMO, AIOM, SIAPEC   LANGUAGES:   Italian (native speaker);  English (OET January 2025 Overall band score: B)   PUBLICATIONS:   1.  Onofrio, L .; Gaeta, A.; O.; Cugliari, G.; Gandini, S.; Queirolo, P. Melanoma Brain Metastases: Immunotherapy or Targeted Therapy? A Systematic Review and Meta-Analyses. Appl. Sci.2024, 14,2222. https://doi.org/10.3390/app14062222.  (As 1st author, I contributed to the selection of the literature papers and I was responsible for drafting the majority of the full text, excluding the statistical analyses).  2. Antonio Faiella, Ferdinando Riccardi, Giacomo Cartenì, Martina Chiurazzi,  Livia Onofrio.  The Emerging Role of c-Met in Carcinogenesis and Clinical Implications as a Possible Therapeutic Target, Journal of Oncology, vol. 2022, Article ID 5179182, 12 pages, 2022. https://doi.org/10.1155/2022/5179182.(I was responsible for drafting the majority of the full text and bibliographic research).  3. Faiella A,  Onofrio L , Liccardi F, Paladino F, Chiurazzi M, Riccardi F, Chiurazzi B. Oncological assistance in the emergency room setting: the role of a dedicated oncology unit. International Journal of Cancer Management.2021 Aug 14(7); e110512.DOI: 10.5812/ijcm.110512.(I actively contributed to the drafting of the paper by analyzing the data produced by Dr. Chiurazzi Bruno during his specialist consultations at the Emergency Room of Cardarelli Hospital in Naples).  4. Ferro M, Lucarelli G, Crocetto F, Dolce P, Verde A, La Civita E, Zappavigna S, de Cobelli O, Di Lorenzo G, Facchini BA, Scafuri L, Onofrio L, Porreca A, Busetto GM, Sonpavde G, Caraglia M, Klain M, Terracciano D, De Placido S, Buonerba C. First- line systemic therapy for metastatic castration-sensitive prostate cancer: An updated systematic review with novel findings. Crit Rev Oncol Hematol. 2020 Dec 13;157:103198. DOI: 10.1016/j.critrevonc.2020.103198. Epub ahead of print. PMID: 33316417.(I contributed to literature research)  5. Di Lorenzo G, Zappavigna S, Crocetto F, Giuliano M, Ribera D, Morra R, Scafuri L,Verde A, Bruzzese D, Iaccarino S, Costabile F,  Onofrio L , Viggiani M, Palmieri A, De Placido P, Marretta AL, Pietroluongo E, Luce A, Abate M, Navaeiseddighi Z, Caputo VF, Ce- lentano G,Longo N, Ferro M, Morelli F, Facchini G, Caraglia M, De Placido S, Buonerba C. Assessment of Total, PTEN-, and AR- V7+ Circulating Tumor Cell Count by Flow Cytometry in Patients with Metastatic Castration-Resistant Prostate Cancer Receiving Enzalutamide. Clin Genitourin Cancer. 2021 Oct;19(5):e286-e298. doi: 10.1016/j.clgc.2021.03.021. Epub 2021 Apr 3. PMID: 33958297.(I participated to cancer patients care).  6. Galli F, Varani M, Lauri C, Silveri GG,  Onofrio   L,  Signore A. Immune cell labelling and tracking: implications for adoptive cell transfer therapies. EJNMMI Radiopharm Chem.2021Feb 3;6(1):7.DOI:10.1186/s41181-020- 00116-7.PMID:33537909;PMCID: PMC7859135.(I authored the section related to CAR-T and CAR-NK adoptive therapies).  7.  Onofrio   L , Caraglia M, Facchini G, Margherita V, De Placido S, Buonerba C. Toll-like receptors and COVID-19: a two-faced story with an exciting ending. Future Sci OA. 2020 Jul 30;6(8): FSO605. DOI:10.2144/fsoa20200091.PMID:32974046;PMCID: PMC7434222.(Dr. Buonerba and I were the principal authors, contributing equallyto the writing of this paper).8. Signore A, Lauri C, Auletta S, Varani M, Onofrio L, Glaudemans W.J.M. A, Panzuto F and Marchetti P. Radiopharmaceuticals for Breast Cancer and Neuroendocrine Tumors: Two Examples of How Tissue Characterization May Influence the choice of therapy. Cancers 2020, 12(4), 781; DOI:10.3390/cancers12040781.(I contributed by providing my clinical expertise in medical oncology).  9.  Onofrio   L,  Buonerba C, Isoquercetin in bladder cancer: a perspective of current potential uses in clinical practice and future directions in clinical research, (2019) Journal of Genitourinary Research and Practice, 1 (2), pp. 27-30. https://doi.org/10.15866/irege.v1i2.18914.  10. A Facciorusso, M Stanislao, C Vigna, V Triggiani, E Guastamacchia,  L Onofrio  and G Valle.Tako- Tsubo Cardiomyopathy: An Underdiagnosed Disease? BAOJ Pall Medicine 2017.3:12:025..(I presented this paper at the 6th International Research Conference in Manchester in August 2016).   OTHER PUBLICATIONS:   "Lo streben e l'insonnia" - Booksprint Edizioni, 2013 "VOCEVERSO - Il fare del poeta" (Libraduepuntozero Ed. 2015)Co-authorship with F Riccardi: First-Line Therapy in Hormone-Receptor-Positive Metastatic Breast Cancer: A Case of Endocrine Resistance. Case report n. 8. Treatment of Breast Cancer with Abemaciclib: Clinical Practice Experiences. Vol II. Journal Edited by M De- Laurentiis & S De Placido   CONFERENCE ABSTRACTS:    L Onofrio,  S Crossley, D J White, S Vimal, A Clipson, C Dive, S Valpione, F Mouliere Impact of Freeze-Thaw Cycles on cfDNA Quality in Liquid Biopsy.(Poster presentations: Colloquium, Buxton, UK. October 9th-11th; Bicentennial of the School of Medical Sciences, Manchester 17th December 2024).   L Onofrio,  A Gaeta, O, S Gandini, P Queirolo. 25th AIOM National Congress. 10th-12th Nov 2023. Mela- noma brain metastases: immunotherapy or target therapy? A systematic review and meta- analyses.Castelli S., Arasi S., Tripodi S., Villalta D., Martelli P., Conte M., Panetta V., Simonelli I., Rohrbach A., Di Fraia M., Sfika I., Villella V., Di Rienzo BusincoA., Perna S., Dramburg S., Potapova E., OnofrioL., R. andMatricardi detection of IgE to allergenic molecules in nasal secretions: implications for the diagnosis of allergic rhino- conjunctivitis. Allergology and Clinical Immunology Nov 28-30, 2019, Matera (Italy), DOI: 10.13140/RG.2.2.13773.18402.   Onofrio L , Valle G, Stanislao M, Facciorusso A. Tako Tsubo Prevalence. World Journal of Medical Education and Research.   SPEAKER IN NATIONAL CONFERENCES:   Milan, 16th Feb 2024: PATRON: upgrading skills through collaboration. Management of patients treated with immunotherapy.  9th March 2022 Webinar live: 2nd season. Stories of melanoma: from adjuvant to metastatic;  2nd March 2021. 1st AIMS National Congress on Scientific Research and Development in the era of medical multidisciplinarity;  16th Dec 2020. 15th Health Forum Risk Management. Good practise in the era of COVID.   PUBLICATION I REVIEWED:   Wang L, HensleyCR, Howell ME, Ning S. Bioinformatics-Driven Identification of p62 as a Crucial Oncogene in Liver Cancer. Front Oncol. 2022 Jun 24;12:923009. doi: 10.3389/fonc.2022.923009. PMID: 35814476; PMCID: PMC9263135.  Monaca F, Vita E, Lococo F, et al. (July 23, 2024) Lazarus Response to Selpercatinib for Bleeding Colic Metastasis in a Patient With RET Fusion-Positive Pulmonary Sarcomatoid Carcinoma: A Case Report. Cureus 16(7): e65186. doi:10.7759/cureus.65186.   GRANTS:   SITC Spring Cellular Therapy for Solid Tumors (12th-14thMarch of2025,Virtual from San Diego,CA)  AFFILIATIONS:  CoLFS Award from University of Manchester, United Kingdom £2000,00 (Aug 2024)ESMO Preceptorship in Gastric Cancer, Lisbon, Portugal 09/2024  ESMO Course on Precision Oncology in Oncogene-Addicted NSCLC: BRAF, KRAS, Rare EGFR, 09/2023  Erasmus International Thesis Scholarship, €2000 (July2017).   TRAININGS:   March- April 2024: Radiotherapy Complex Operational Unit, Policlinico Tor Vergata;  Jan - Feb 2024: Emergency: First Aid C omplex Operational Unit, Policlinico Tor Vergata.  Nov-Dec 2023 Palliative Care: ESMO Designed Centre San Raffaele S.p.A. Hospice Cassino.  Nov 2023 PhD Course: Mechanisms of Cancer, Cancer Biology &Translational Cancer Research, Univ. of Copenhagen.  8th-10th October 2019. Microbes, immunity and cancer, Ruggero Ceppellini Immunology School, Capri.  2018- 2019 Italian Academy of Resident Doctors (AIMS)  9th - 10th Feb 2019 Workshop: Labelling of Autologous Leukocytes with Leukokit® University.  Oct - Dec 2017 Internal Medicine Internship (Immunology and Rheumatology, Sant'Andrea Hospital  Aug 2016. Future Excellence 8th International Medical Summer School, Doctors Academy,University of Manchester (UK).  Sept 2010- Sept 2011. Biotechnology Course at the University of Rome La Sapienza.   EDUCATIONAL EVENTS:   Rome, 7th Oct 2018. Cancer prevention and fundraising: "Bikers vs Cancer" hosted by "Due ruote per la speranza" association. 

Dedicated and compassionate Physician Assistant Student who is highly motivated to conduct thorough patient assessments, diagnose medical conditions, and implement effective treatment plans. Proficient in performing during high stress situations due to my military background in the medical field. Strong ability to communicate with patients, families, and medical staff to ensure comprehensive and personalized care. Adept at managing medical records and maintaining a high level of accuracy and confidentiality. Seeking to leverage my expertise and passion for patient care in a dynamic healthcare environment.

Dr.KARUNAKAR SANGISHETTI

Summary

Overview

Work History

LEPROSY MEDICAL OFFICER

A.R.T MEDICAL OFFICER

A.R.T MEDICAL OFFICER

Education

8TH CLASS To 10 TH CLASS

INTERMEDIATE

M.B.B,S

A.R.T (ANTI RETRO VIRAL THERAPY)TRAINING

C.C.P.P.M (PAIN &PALIATIVE MEDICINE)

Skills

Timeline

C.C.P.P.M (PAIN &PALIATIVE MEDICINE)

LEPROSY MEDICAL OFFICER

A.R.T MEDICAL OFFICER

A.R.T MEDICAL OFFICER

A.R.T (ANTI RETRO VIRAL THERAPY)TRAINING

M.B.B,S

INTERMEDIATE

8TH CLASS To 10 TH CLASS

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