Dr M P DURGA PRASAD
Hyderabad
Summary
Professional with ten years of experience in biological product manufacturing, specializing in biosimilars, probiotics, and wastewater treatment. Expertise in developing Escherichia coli-based solutions for pharmaceutical and biotechnology applications. Proven ability to optimize manufacturing processes and scale technologies to ensure quality compliance. Demonstrated leadership in managing operations and enhancing team collaboration to drive efficiency and productivity.
Overview
17
17
years of professional experience
Work History
R&D Scientist
Loka Biosciences Private Limited
Hyderabad
07.2025 - Current
- Designed alcohol dehydrogenase-expressing probiotics to facilitate ethanol metabolism.
- Lowered blood alcohol levels significantly through targeted gastrointestinal interventions.
- Mitigated risks of organ damage linked to alcohol consumption with engineered solutions.
- Created recombinant probiotics aimed at improving gut health in controlled environments.
Deputy Manager R&D
Promea Therauptics Private Limited
Hyderabad
07.2024 - 06.2025
- Developed monoclonal antibodies for therapeutic applications, enhancing research outcomes.
- Led projects to optimize production processes for E. coli-based recombinant proteins, improving yield and quality.
- Executed cloning, PCR, bacterial transformation, and plasmid preparation to facilitate protein expression.
- Conducted in vitro transcription and protein expression analysis utilizing ELISA, Western blotting, SDS-PAGE, and purification techniques.
Deputy Manager R&D
Blueweight Biosciences Private Limited
Vijayawada
03.2022 - 06.2024
- Led interdisciplinary team in developing a white spot syndrome virus vaccine using advanced RNA interference technology to enhance shrimp health.
- Monitored experimental results to refine product formulations, improving efficacy and safety of biotechnological solutions for aquaculture health management.
- Isolated and characterized bacteriophage strains from sewage samples, contributing to microbial control strategies in aquaculture.
Assistant Manager R&D
Virchow Biotech Private Limited
Hyderabad
08.2020 - 02.2022
- Optimized production of E. coli-based recombinant proteins and probiotics through media and condition adjustments at shake flask, lab-scale fermenter, and pilot-scale levels, improving yield and consistency.
- Executed advanced downstream processing techniques including continuous centrifuge, high-pressure homogenization, and purification processes, ensuring high-quality output of protein products.
- Managed manpower allocation and trained new employees on SOPs and on-the-job protocols, ensuring compliance with GMP, ICH, and 21CFR standards throughout production processes to maintain quality control.
- Conducted meticulous isolation and identification studies of probiotic cultures from various environmental sources, utilizing PCR and sequencing for validation via 16S rDNA analysis.
Assistant Manager R&D
Unique Biotech Limited
Hyderabad
12.2017 - 07.2020
- Managed the operation and scaling of lab to pilot-scale fermenters, ensuring effective production of high-quality probiotic cultures.
- Optimized media composition and performed stability studies for probiotic cultures, including Bacillus, Lactobacillus, Bifidobacterium, and Streptococcus, utilizing shake flask and lab-scale fermentation to improve culture performance.
- Conducted studies on probiotic properties of microorganisms, emphasizing health benefits and applications in formulation development.
- Executed downstream processing operations, including spray drying, lyophilization, and enzyme extraction, to enhance viability and stability of probiotic formulations.
- Utilized advanced molecular biology techniques, including DNA isolation, SDS-PAGE, and agarose gel electrophoresis, for rigorous analysis of microbial strains.
Project Associate
Innotech Interventions Private Limited
Hyderabad
02.2017 - 09.2017
- Designed and fabricated bioreactors, specifically microbial fuel cells, to enhance bio-treatment processes for petroleum wastewater.
- Utilized bio-electrochemical systems to effectively treat petroleum produced water, enhancing water quality and promoting environmental sustainability.
- Conducted analyses of petroleum produced water characteristics pre- and post-treatment, applying standard methods to evaluate treatment efficacy.
- Isolated and purified specific bacteria using tailored growth media, enabling detailed study of microbial behavior in petroleum degradation.
Technical Assistant
Harrison Biotechnologies
Nellore
05.2009 - 10.2010
- Assisted in laboratory sample preparation, addressing technical challenges through diligent monitoring and precise protocol execution to ensure accurate results.
- Performed comprehensive water analysis using standard laboratory techniques to assess contamination levels and ensure compliance with safety regulations.
- Conducted microbial cell culture experiments, optimizing growth conditions and maintaining sterile environments to enhance research project outcomes.
Education
Ph.D. - Chemical Engineering
Andhra University
Visakhapatnam11-2017
M.Tech. - Biotechnology
Institute of Science And Technology, JNTUK
Kakinada10-2012
B.Tech - Biotechnology
Audisankara College of Engineering & Technology
Nellore06-2009
Skills
- Recombinant technology
- Fermentation techniques
- Protein purification methods
- AKTA Pure systems
- Analytical methods
- Process development strategies
- Project management
Publications
- A Review on Treatment of Sugar Industry Effluents, i-Manager’s Journal On Future Engineering & Technology, 9, 3, 02/01/14
- Treatment of Pharmaceutical Waste Water by Exigency Methods: A Review, Indian Journal Of Applied Research, 4, 10, 10/01/14, 2249-555X, 2.16
- Treatment of Sugar Industry Effluent using Microbial Fuel Cells (MFC), Science, Technology and Arts Research Journal (STAR), 04/01/15, 4, 2, 247-251, 1.638, http://dx.doi.org/10.4314/star.v4i2.34
- Treatment of Coal gasifier effluent using Electrocoagulation studies and its Optimization, Bioresource. Technol., under communication
- Pongamia Pinnata seed powder for the treatment of coal gasification wastewater through adsorptive removal: Optimization studies, Emergent Materials (EMMA), under communication
Volunteer Experience
Active Member, Prakrithi, a biotechnologists association.
Extracurricular Activities
Computer Proficiency, Proficiency in Computer Operating systems MS Office, Excel, PowerPoint, Adobe Photoshop and related tools. Blood Donation, Donated blood two times at blood donation camps held at our college. Skit Competition, Got 1st prize in skit competition conducted on our college annual day. Participated in sports held at college and school level. Member of Prakrithi, An active member in Prakrithi, a biotechnologists association.
Projects
- Treatment of Petroleum Produced Water using Bioelectrochemical System (BES), 02/01/17, 08/31/17
- A comparative study on electrocoagulation and adsorption in reduction of chemical oxygen demand (COD) in coal gasifier effluent – optimization, 01/01/13, 10/31/16
- Studies on fermentative production of citric acid by Aspergillus niger isolate using sorghum malt and its optimization by response surface methodology, 01/01/12, 10/31/12
Timeline
R&D Scientist
Loka Biosciences Private Limited
07.2025 - Current
Deputy Manager R&D
Promea Therauptics Private Limited
07.2024 - 06.2025
Deputy Manager R&D
Blueweight Biosciences Private Limited
03.2022 - 06.2024
Assistant Manager R&D
Virchow Biotech Private Limited
08.2020 - 02.2022
Assistant Manager R&D
Unique Biotech Limited
12.2017 - 07.2020
Project Associate
Innotech Interventions Private Limited
02.2017 - 09.2017
Technical Assistant
Harrison Biotechnologies
05.2009 - 10.2010
Ph.D. - Chemical Engineering
Andhra University
M.Tech. - Biotechnology
Institute of Science And Technology, JNTUK
B.Tech - Biotechnology
Audisankara College of Engineering & Technology