Dr. PADMA SUDHA RANI LAVU
Guntur
Summary
§ Over 15+ years’ of diversified experience in the areas of Microbiology and Molecular biology in food and feed testing (ISO17025, EIC, APEDA, and FSSAI) and Research & development.
§ Worked as a Technical manager, Lecturer, chemist, Research Fellow, DST-Women Scientist –A as a principle investigator.
§ Experience in laboratory operations, quality management systems, streamlines the facility of testing analysis and method development/validation/verification.
§ Well experienced in handling technical and business queries for troubleshooting assays of allergen detection by ELISA, Real time PCR- molecular based assays for GMO, allergens microbial pathogens detection, PCR based assays for meat species identification and WSSV detection.
§ Hands on microbiological examination of water and various food matrices by using conventional and rapid screening techniques.
§ Ensuring the quality compliance of the laboratory according to ISO 17025: 2017.
§ Exposure in set up of food testing microbiological laboratory as per the standard requirement.
§ Ph.D. in Microbiology on topic entitled, “Development of Aptamer based detection systems for the important food borne pathogens of family Enterobacteriaceae”.
§ Competencies in carrying out complex analytical work. Gather data through observation, analysis and experiments. Study chemical composition of living things at the molecular level, as well as the chemical reactions that regulate life.
§ Ability to establish priorities and to plan, coordinate and monitor own work plan and the team. Equipped with the willingness to learn to keep abreast of new developments in the field of life sciences.
§ Well competent in teaching PG & UG students for Microbiology, Biotechnology, Medical Microbiology and Biochemistry.
§ Results-driven scientific professional with robust background in laboratory management and focus on precision and efficiency. Brings history of successful leadership and operational effectiveness. Known for teamwork, adaptability, and fostering collaborative environments. Expertise in regulatory compliance and laboratory process optimization.
Overview
20
20
years of professional experience
Work History
Deputy Manager- Biology
Chemtex Labs India Pvt Ltd
07.2024 - Current
- Developed strong relationships with stakeholders to facilitate smooth communication and laboratory operations.
- Supervised day-to-day operations to meet performance, quality and service expectations.
- Created and maintained a strong team culture that promoted high levels of collaboration, employee satisfaction, and overall performance.
- Developed detailed plans based on broad guidance and direction.
- Collaborated with cross-functional teams to drive business growth and achieve corporate objectives.
- Maintained positive customer relations by addressing problems head-on and implementing successful corrective actions.
- Mentored junior staff members in their professional development by offering guidance/support in their assigned roles.
- Improved customer satisfaction by addressing and resolving complaints promptly.
- Trained personnel in equipment maintenance and enforced participation in exercises focused on developing key skills.
- Coordinated with vendors for timely inventory replenishment, ensuring product availability.
- Skilled at working independently and collaboratively in a team environment.
- Worked effectively in fast-paced environments.
- Managed time efficiently in order to complete all tasks within deadlines.
Associate, Technical Manager, Molecular biology
ITC
05.2022 - 05.2023
- End to end handling of molecular biology laboratory operations and quality management system as per ISO/IEC 17025:2017.
- Handling of regulatory (NABL) and customer audits in compliance.
- Conducting the GMO detection, allergen testing, meat species identification, rapid testing of pathogens and virus testing by RTPCR/ PCR/ ELISA based methods.
- Designing and conducting R&D projects and allocating resources and timelines.
- Verifying & maintaining all the logbooks and quality documents in compliance with ISO/IEC 17025: 2017.
- Handling all procurement, rate negotiation, vendor selection and inventory management.
- Understanding of cost sheet preparation for the test method development.
- Maintain in-time supply of all laboratory consumables and maintain the record for the same.
- Providing test feasibility's and technical inputs to the customer queries.
- Conduct root cause analysis and implement corrective actions.
- Implement, monitor and verify closure of non-conformances raised during the audit.
- Plan and organize annual trainings & IQC schedules, handling and conducting of IQC, ILC and PT programs, handling of PT samples and qualifying for the same.
- Arranging the in-time calibration, servicing and repairs of the instruments in Molecular biology lab and maintaining the record for the same.
- Maintaining intermediate checks of major instruments.
- Monitoring of storage, maintenance and discard of remnant samples at controlled condition and its record verification.
- Supervising the environmental hygiene, cleanliness of the molecular biology lab and verifying relevant records.
- CRMs, Critical consumables evaluation, preparation and maintenance.
- Perform internal audits for strict maintenance of lab quality management system.
- Technical skills, knowledge and experience: Proficient in handling GMOs, meat speciation, rapid pathogen and allergen testing and well versed with major instruments like, PCR, RTPCR and ELISA.
- Communicate weekly lab updates to the business head establish connections in the market with vendors, competitors etc.
- Capacity building and skill development of the molecular biology team as per the market demand and changing regulatory requirement.
- Preparation of SOPs and method validation reports.
- Interpretation of correct test results and performs troubleshooting activities.
- Sharing experimental evidences to satisfy queries raised by internal or external client.
- Risk identification, action plan, execution and monitoring in the molecular biology laboratory and able to work cross functionally.
Ph.D. Scholar
Defence Food Research Laboratory, DRDO
11.2012 - 12.2020
- Women Scientist A (WOS-A), Department of Science and technology (DST) as Principle investigator Ph.D.
- Collaborated with fellow scholars for interdisciplinary research projects, resulting in high-quality publications and presentations.
- Enhanced research capabilities by implementing innovative methodologies and techniques in scholarly studies.
- Used critical thinking to break down problems, evaluate solutions and make decisions.
- Organized and participated in outreach events aimed at promoting public understanding of scholarly research and its implications for society.
Technical manager, Microbiology
Annoor Envirochem and food analytical laboratory
04.2018 - 05.2019
- Set up of food testing microbiological laboratory as per the standard requirement 17025.
- Allotting and distributing the work, reviewing of Sops, reports and raw data.
- Hands on microbiological examination of water and various food matrices by using conventional methods
- Evaluate current testing technologies for performance/applicability in the analysis of specified matrices.
- Knowledge of ISO 17025 laboratory accreditation, a plus.
- Ensure that the laboratory operates with calibrated equipment and carryout performance, qualification of the equipment, as per the frequencies.
- Support the validation activities in terms of design, operational and performance qualification of the process and laboratory equipment’s.
Lecturer
VIGNAN SCHOOL OF PG STUDIES
01.2007 - 01.2011
- Lecturer for PG & UG students for Microbiology, Immunology and medical microbiology, Food microbiology course.
- Hands on training and practical’s for PG students in Microbiological and Immunological Techniques - Chromatography: Paper Chromatography, Thin Layer Chromatography.
- Molecular biology: AGE, RID, ELISA, Immunoelectrophoresis.
- Productions: Wine, Protease, Citric acid, Penicillin, Cell immobilization.
- Assays: Antibiotics, Vitamin.
- All microbiological techniques including isolation and maintenance of pure cultures.
Trainee chemist
CARGILL MATRIX FEEDS PVT LTD
01.2006 - 01.2007
- Determination of ash and sand silica by using muffle furnace.
- Determination of Protein by kjeldhal method.
- Determination of neutral detergent fiber, acid detergent fiber crude fat extraction by Soxhlet method.
Lecturer
CR REDDY WOMENS COLLEGE
05.2005 - 06.2006
- Lecturer for PG & UG students for Microbiology, Immunology and Medical microbiology, Biochemistry, Medical lab technology course.
- Hands on training and practical’s for PG students in Microbiological and Immunological Techniques.
- Divisional Administrative Duties.
Education
Ph.D. - Microbiology
Bharathiyar University
Coimbatore, India12-2020
Master of Philosophy - Microbiology
Bharathiyar University
Coimbatore, India04-2014
Master of Science - Microbiology
Andhra University
Visakhapatnam, India04-2005
Bachelor of Science -
Nagarjuna University
Guntur, India04-2003
Skills
- Capex price negotiations
- Laboratory management system
- Research expert
- Project management
- Data analysis & management
- Modern molecular biology & Microbiology techniques expert
- Method Development & validations
- Rapid test evaluations
- Analytical Skills
- Capability development
- Communication Excellence
- Creative thinking & Adaptability
Accomplishments
Credentials of qualifying:
§ DRDO JRF 2012
§ Selected for Women scientist A (WOS-A)
Department of Science and Technology (DST), 2013.
Awards& Honors:
§ Received DRDO, Path breaking research award for outstanding technology development, 2015, Ministry of Defence, Govt of India.
§ 6TH RANK inM.Sc. Microbiology, Andhra University,2005.
§ Area topper in S.S.C and B.sc
Patents:
§ A Combinatorial Improved Method for the selection of aptamers for protein targets"
Application id.: 2720/DEL/2014.
Publication Number: 14/2016.
Products Developed and validated:
§ Aptamer-antibody based detection kit for Salmonella Typhimurium (Apt-Ab hybrid ELISA).
§ Gold nanoparticle based colorimetric detection of Enterotoxin B (Staph GNP Kit).
§ Apta Real time PCR based detection System for E.coli.
Symposium / Workshop attended
§ Indian online Science Symposium: Biolimb varsity, Cloud Theatre, 29th April-1st May 2016.
§ Active member for Hands on training for Army, Navy, Air force staff for Microbiology, Immunological and Molecular technology for pathogen detection conducted in DFRL, DRDO.
Grant Acquisition for Research:
§ Women Scientist A (WOS-A), Department of Science and technology (DST) as a PrincipleInvestigator for the period of 2013 – 2016.
Guest Lectures:
§ Biotechnology awareness program for the students of B Pharmacy and Pham D of KVSR Siddhartha College of Pharmaceutical Sciences.
Languages
English
Bilingual or Proficient (C2)
Hindi
Intermediate (B1)
Telugu
Bilingual or Proficient (C2)
PUBLICATIONS
Publications:
§ Lavu, Padma Sudha Rani, Bhairab Mondal, Shylaja Ramlal, Harishchandra Sreepathy Murali, and Harsh Vardhan Batra. "Selection and characterization of aptamers using a modified whole cell bacterium SELEX for the detection of Salmonella entericaserovar Typhimurium." ACS combinatorial science 18, no. 6 (2016): 292-301.(Impact Factor-3.381), https://doi.org/10.1021/acscombsci.5b00123
§ Lavu, Padma Sudha rani, Bhairab Mondal, and Shylaja Ramlal. "Selection and Characterization of Cell Surface Specific Aptamer and Development of Fluorescence Assay for Detection of Shigella flexneri from Water Samples." Journal of Fluorescence 31, no. 3 (2021): 685-693. (Impact Factor- 2.6), https://doi.org/10.1007/s10895-021-02691-7
§ Mondal, Bhairab, Shylaja Ramlal, Padma Sudha Rani Lavu, Harishchandra Sreepathy Murali, and Harsh Vardhan Batra. "A combinatorial systematic evolution of ligands by exponential enrichment method for selection of aptamer against protein targets." Applied microbiology and biotechnology 99, no. 22 (2015): 9791-9803.(Impact Factor-3.9),https://doi.org/10.1007/s00253-015-6858-9
§ ShylajaRamlal,BhairabMondal, PadmaSudharaniLavu, BhavanashriN, .JosephKingston. “Capture and detection of Staphylococcus aureus with dual labeled aptamers to cell surface components”. International Journal of Food Microbiology.Volume 265, 16 January 2018, Pages 74-83. (Impact Factor-5.0),https://doi.org/10.1016/j.ijfoodmicro.2017.11.002
§ Bhairab Mondal, Shylaja Ramlal, Padma Sudha Rani Lavu, Bhavanashri N and Joseph Kingston “Highly Sensitive Colorimetric Biosensor for Staphylococcal Enterotoxin B by a Label-Free Aptamer and Gold Nanoparticles” Front. Microbiol., 13 February 2018. (Impact Factor-4.0).https://doi.org/10.3389%2Ffmicb.2018.00179
References
References:
1.Dr. Shylaja Ramlal,
Scientist, Department of Microbiology,
Defence Food Research Laboratory,
Siddartha Nagar, Mysore.
Phone number: 9480447388
Email Id: shylajaramlal1@gmail.com
2. Dr.Bhairab Mondal
Designated partner,
Shankarnayana life sciences, Bengaluru
Karnataka.
Phone number: 8095961994
Email Id:bhairabmicro21@gmail.com
Declaration
I deem it privilege to be employee of your firm. I assure you that if appointed I will do my best to rise to the expectation of my superiors.
Thanking you.
Your’s sincerely,
(Dr. L. PADMA SUDHA RANI)
Timeline
Deputy Manager- Biology
Chemtex Labs India Pvt Ltd
07.2024 - Current
Associate, Technical Manager, Molecular biology
ITC
05.2022 - 05.2023
Technical manager, Microbiology
Annoor Envirochem and food analytical laboratory
04.2018 - 05.2019
Ph.D. Scholar
Defence Food Research Laboratory, DRDO
11.2012 - 12.2020
Lecturer
VIGNAN SCHOOL OF PG STUDIES
01.2007 - 01.2011
Trainee chemist
CARGILL MATRIX FEEDS PVT LTD
01.2006 - 01.2007
Lecturer
CR REDDY WOMENS COLLEGE
05.2005 - 06.2006
Ph.D. - Microbiology
Bharathiyar University
Master of Philosophy - Microbiology
Bharathiyar University
Master of Science - Microbiology
Andhra University
Bachelor of Science -
Nagarjuna University
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