Dr Sukeerthi Kumar
Flat No 25, Building No 4-B Bhudargad CHS Andheri West Mumbai
Summary
Friendly Principal Scientist with 24 years of technical experience in organic synthesis/medicinal chemistry. Excellent strategic planning, communication, and relationship-building expertise.
Overview
23
23
years of professional experience
1
1
Certification
Work History
Principal Scientist
Glenmark pharmaceutical Ltd
Navi Mumbai
04.2011 - 06.2024
- Managed a team of 13 researchers, providing guidance and direction on project goals.
- Worked on several projects in the oncology and inflammation area including small molecule modulators of given therapeutic targets.
- The role involved designing feasible synthetic strategies and execution of synthesis by troubleshooting the challenges that occurred during synthesis by literature search and by understanding the deep crux of the reaction.
- Design of PROTACs and inhibitors library for immuno-oncology program
- Designed innovative strategies to improve laboratory efficiency and productivity.
- Created detailed reports summarizing the progress of ongoing research initiatives.
- Evaluated new technologies for potential application in drug discovery processes.
- Organized regular meetings with senior management regarding project updates.
- Provided mentorship and support to junior scientists within the organization.
- Coordinated early stability programs for drugs in early clinical stages of development.
- Designed and executed research programs.
- Supervised junior scientists and laboratory technicians, providing mentorship and training.
Senior Research Scientist
Glenmark pharmaceutical Ltd
Navi Mumbai
01.2010 - 03.2011
- Analysis of in vitro and in vivo results/biweekly presentation of consolidated SAR/DMPK results to the higher management under guidance of Director
- Prepared detailed reports summarizing findings from research projects for Patent
- Communicated project progress updates at regular intervals with team members via email or conference calls.
- Attended industry conferences and meetings to stay abreast of new theories and findings.
- Supported organization in maintaining work environment focused on scientific integrity and quality while fostering learning, open communication, collaboration and teamwork.
Research Scientist
Glenmark pharmaceutical Ltd
Navi Mumbai
12.2005 - 12.2009
- Performed literature reviews to stay abreast of current developments in the field of research science.
- Provided technical support during presentations of project progress at internal meetings or external events.
Postdoctoral Researcher
Centre national de la recherche Scientifique
Paris
02.2002 - 12.2005
Postdoctoral Researcher
Ciba
Mumbai
01.2001 - 01.2002
Education
Ph.D. - Organic Chemistry
University of Mumbai
Maharashtra India06-2001
Master of Science - Organic Chemistry
Mumbai University
Maharashtra India04-1995
Bachelor of Science - Chemistry
Mangalore University
Karnataka 03-1991
Skills
- Organic chemistry expertise
- Expertise in Medicinal Chemistry
- Excellent Communication
- PROTAC synthesis
- Multistep synthesis
- Macrocycles
- Analytical data interpretation
Accomplishments
- Chairman's Excellence Award for individual excellence in metabolite synthesis for inflammatory Project 2015
- Chairman's Excellence Award for best team innovation for immuno oncology project 2019
- Chairman's Excellence Award for best team innovation for immuno oncology project 2014
Certification
- ChemInform Abstract: One-Pot Synthesis of Highly Substituted Nicotinic Acid Derivatives Based on a Formylation Strategy of Enamino Keto Esters. ChemInform 47(28) June 2016 DOI:10.1002/chin.201628174
- One-Pot Synthesis of Highly Substituted Nicotinic Acid Derivatives Based on a Formylation Strategy of Enamino Keto Esters Journal of Organic Chemistry 81(4) February 2016 81(4) DOI:10.1021/acs.joc.5b02796
- Fused pyrimidine-dione derivatives as TRPA1 modulators Patent: US9000159B2 April 2015
- 2-amino-4-arylthiazole compounds as TRPA1 antagonists Patent: US8889862B2 November 2014
- A simple and general approach for the synthesis of highly functionalized 6-oxo-1,6-dihydropyridines Tetrahedron Volume 69, Issue 25, 24 June 2013, Pages 5112-5118 https://doi.org/10.1016/j.tet.2013.04.082
- 2-Amino-4-arylthiazole derivs. as TRPA modulators useful in treatment and prevention of of TRPA1-mediated diseases, and preparation there of patent: US 20120157411, A1 June 2012
- ChemInform Abstract: Synthesis of New Crown Analogues Derived from Bisphenol. ChemInform 29(37)
- September 2010 DOI:10.1002/chin.199837197
- ChemInform Abstract: Synthesis of Macrocycles Derived from Vanillin and Isovanillin.Indian Journal of Chemistry 40B(23):5-10 June 2010 DOI:10.1002/chin.200123037
- ChemInform Abstract: Aqueous Micellar Medium in Organic Synthesis: Alkylations and Michael Reactions of Benzotriazole ChemInform 33(12) March 2010 DOI:10.1002/chin.200212163
- [3.3]Dithia-bridged cyclophanes featuring a thienothiophene ring: Synthesis, structures and conformational analysis Beilstein Journal of Organic Chemistry 5(1) December 2009 DOI:10.3762/bjoc.5.74
- Synthesis of conformationally constrained analogues of RGD tripeptide Tetrahedron 63(9) February 2007 DOI:10.1016/j.tet.2006.12.020
- Synthesis of 4-Substituted-3-aminopiperidin-2-ones: Application to the Synthesis of a Conformationally Constrained Tetrapeptide N -Acetyl-Ser-Asp-Lys-Pro The Journal of Organic Chemistry 70(15):5946-53 August 2005 DOI:10.1021/jo050736k
- Fluorescence properties of crown ethers with phenylbenzothiozole pendant group Chemical Physics Letters 408(4-6) June 2005 DOI:10.1016/j.cplett.2005.04.032
- Dipyridyl/pyridinium thieno [2,3-b]thiophenes as new atropisomeric systems. Synthesis, conformational analysis and energy minimization Tetrahedron 61(14):3507-3513 April 2005 DOI:10.1016/j.tet.2005.01.123
- Synthesis, molecular structure and optical spectral studies of syn-dithia benzothiazolophane and anti-bis-lactone benzothiazolophane Journal of Molecular Structure 697(1-3):221-230 July 2004 DOI:10.1016/j.molstruc.2004.04.014
- Synthesis, Cation-Binding and Optical Spectral Studies of Photoemmitive Benzothiazole Crown Ethers Journal of Inclusion Phenomena 48(3):125-130 April 2004 DOI:10.1023/B:JIPH.0000022531.17974.fb
- Synthesis and Conformational Analysis of syn-Dithia[3.3][2,4]thiazolophane (I) and syn-Dithia[3.3]([1,4]phenyl[2,4]thiazolophane) (II) ChemInform 34(49) December 2003 DOI:10.1002/chin.200349145
- Synthesis of Anti-[2.2](2-Phenylthiazolophane): A New Heterocyclic Biphenylophane Journal of Chemical Research 2003(6):351-353 June 2003 DOI:10.3184/030823403103174083
- Synthesis of anti-[2.2] (2-phenyl thiazolophane): A New heterocyclic biphenylophane. Journal of Chemical Research January 2003 6:351-353
- Synthesis and conformational analysis of dithia syn [3.3][2,4] thiazolophane and dithia syn [3.3] (1,4phenyl-[2.4]thiazolophane,Journal of Chemical Research January 2003 4:225-227
- Aqueous Micellar Medium in Organic Synthesis: Alkylations and Michael Reactions of Benzotriazole Aqueous Micellar Medium in Organic Synthesis. Bulletin of the Chemical Society of Japan 74(11):2133-2138 November 2001 DOI:10.1246/bcsj.74.2133
- Attempt Towards Syn-Benzothiazolophane: Synthesis and Conformational Studies of Syn-dithia-[3.3](2,6) Benzothiazolophane Heterocyclic Communications 7(1):73-75 February 2001 DOI:10.1515/HC.2001.7.1.73
- Synthesis of macrocycles derived from vanillin and isovanillin ndian Journal of Chemistry -Section B 40(1):5-10 January 2001
- ChemInform Abstract: A Convenient One-Pot Synthesis of 2,5-Functionalized Thieno[2,3-b]thiophenes Using Anhydrous Potassium Fluoride in Dimethylformamide. ChemInform 31(11) December 1999. DOI:10.1002/chin.200011101
- Synthesis of new crown analogs derived from bisnaphthol Indian Journal of Chemistry -Section B 37B(4):348-351 April 1998
- Synthesis of new crown analogs derived from bisphenol Indian Journal of Chemistry 36B(8):656-661 January 1997
Languages
kanada
First Language
Hindi
Advanced (C1)
C1
English
Proficient (C2)
C2
References
References available upon request.
Timeline
Principal Scientist
Glenmark pharmaceutical Ltd
04.2011 - 06.2024
Senior Research Scientist
Glenmark pharmaceutical Ltd
01.2010 - 03.2011
Research Scientist
Glenmark pharmaceutical Ltd
12.2005 - 12.2009
Postdoctoral Researcher
Centre national de la recherche Scientifique
02.2002 - 12.2005
Postdoctoral Researcher
Ciba
01.2001 - 01.2002
Ph.D. - Organic Chemistry
University of Mumbai
Master of Science - Organic Chemistry
Mumbai University
Bachelor of Science - Chemistry
Mangalore University
- ChemInform Abstract: One-Pot Synthesis of Highly Substituted Nicotinic Acid Derivatives Based on a Formylation Strategy of Enamino Keto Esters. ChemInform 47(28) June 2016 DOI:10.1002/chin.201628174
- One-Pot Synthesis of Highly Substituted Nicotinic Acid Derivatives Based on a Formylation Strategy of Enamino Keto Esters Journal of Organic Chemistry 81(4) February 2016 81(4) DOI:10.1021/acs.joc.5b02796
- Fused pyrimidine-dione derivatives as TRPA1 modulators Patent: US9000159B2 April 2015
- 2-amino-4-arylthiazole compounds as TRPA1 antagonists Patent: US8889862B2 November 2014
- A simple and general approach for the synthesis of highly functionalized 6-oxo-1,6-dihydropyridines Tetrahedron Volume 69, Issue 25, 24 June 2013, Pages 5112-5118 https://doi.org/10.1016/j.tet.2013.04.082
- 2-Amino-4-arylthiazole derivs. as TRPA modulators useful in treatment and prevention of of TRPA1-mediated diseases, and preparation there of patent: US 20120157411, A1 June 2012
- ChemInform Abstract: Synthesis of New Crown Analogues Derived from Bisphenol. ChemInform 29(37)
- September 2010 DOI:10.1002/chin.199837197
- ChemInform Abstract: Synthesis of Macrocycles Derived from Vanillin and Isovanillin.Indian Journal of Chemistry 40B(23):5-10 June 2010 DOI:10.1002/chin.200123037
- ChemInform Abstract: Aqueous Micellar Medium in Organic Synthesis: Alkylations and Michael Reactions of Benzotriazole ChemInform 33(12) March 2010 DOI:10.1002/chin.200212163
- [3.3]Dithia-bridged cyclophanes featuring a thienothiophene ring: Synthesis, structures and conformational analysis Beilstein Journal of Organic Chemistry 5(1) December 2009 DOI:10.3762/bjoc.5.74
- Synthesis of conformationally constrained analogues of RGD tripeptide Tetrahedron 63(9) February 2007 DOI:10.1016/j.tet.2006.12.020
- Synthesis of 4-Substituted-3-aminopiperidin-2-ones: Application to the Synthesis of a Conformationally Constrained Tetrapeptide N -Acetyl-Ser-Asp-Lys-Pro The Journal of Organic Chemistry 70(15):5946-53 August 2005 DOI:10.1021/jo050736k
- Fluorescence properties of crown ethers with phenylbenzothiozole pendant group Chemical Physics Letters 408(4-6) June 2005 DOI:10.1016/j.cplett.2005.04.032
- Dipyridyl/pyridinium thieno [2,3-b]thiophenes as new atropisomeric systems. Synthesis, conformational analysis and energy minimization Tetrahedron 61(14):3507-3513 April 2005 DOI:10.1016/j.tet.2005.01.123
- Synthesis, molecular structure and optical spectral studies of syn-dithia benzothiazolophane and anti-bis-lactone benzothiazolophane Journal of Molecular Structure 697(1-3):221-230 July 2004 DOI:10.1016/j.molstruc.2004.04.014
- Synthesis, Cation-Binding and Optical Spectral Studies of Photoemmitive Benzothiazole Crown Ethers Journal of Inclusion Phenomena 48(3):125-130 April 2004 DOI:10.1023/B:JIPH.0000022531.17974.fb
- Synthesis and Conformational Analysis of syn-Dithia[3.3][2,4]thiazolophane (I) and syn-Dithia[3.3]([1,4]phenyl[2,4]thiazolophane) (II) ChemInform 34(49) December 2003 DOI:10.1002/chin.200349145
- Synthesis of Anti-[2.2](2-Phenylthiazolophane): A New Heterocyclic Biphenylophane Journal of Chemical Research 2003(6):351-353 June 2003 DOI:10.3184/030823403103174083
- Synthesis of anti-[2.2] (2-phenyl thiazolophane): A New heterocyclic biphenylophane. Journal of Chemical Research January 2003 6:351-353
- Synthesis and conformational analysis of dithia syn [3.3][2,4] thiazolophane and dithia syn [3.3] (1,4phenyl-[2.4]thiazolophane,Journal of Chemical Research January 2003 4:225-227
- Aqueous Micellar Medium in Organic Synthesis: Alkylations and Michael Reactions of Benzotriazole Aqueous Micellar Medium in Organic Synthesis. Bulletin of the Chemical Society of Japan 74(11):2133-2138 November 2001 DOI:10.1246/bcsj.74.2133
- Attempt Towards Syn-Benzothiazolophane: Synthesis and Conformational Studies of Syn-dithia-[3.3](2,6) Benzothiazolophane Heterocyclic Communications 7(1):73-75 February 2001 DOI:10.1515/HC.2001.7.1.73
- Synthesis of macrocycles derived from vanillin and isovanillin ndian Journal of Chemistry -Section B 40(1):5-10 January 2001
- ChemInform Abstract: A Convenient One-Pot Synthesis of 2,5-Functionalized Thieno[2,3-b]thiophenes Using Anhydrous Potassium Fluoride in Dimethylformamide. ChemInform 31(11) December 1999. DOI:10.1002/chin.200011101
- Synthesis of new crown analogs derived from bisnaphthol Indian Journal of Chemistry -Section B 37B(4):348-351 April 1998
- Synthesis of new crown analogs derived from bisphenol Indian Journal of Chemistry 36B(8):656-661 January 1997
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