KAMAL RAJ NITHYANANTHAM
SENIOR BIOINFORMATICIAN
BANGALORE
Summary
Biomedical Professional in design, implementation of bioinformatics pipeline for Research and development solutions with 3+ years of experience in Bioinformatics, project management through focused team building and leadership in execution of milestones and deliverables.
Overview
4
4
years of professional experience
5
5
years of post-secondary education
Work History
SENIOR BIOINFORMATICIAN
ZS ASSOCIATES
BANGALORE
04.2022 - Current
- Managed team of employees, overseeing hiring, training and professional growth of employees.
- Received and processed stock into inventory management system.
- Drove operational improvements which resulted in savings and improved profit margins.
- Lead consulting projects for Life Sciences clients focused on process improvements or technology implementations.
- Strong consulting skills, including a high degree of communication and presentation skills, with the ability to manage multiple projects concurrently.
- Developed a clinical and commercial API system to support clinical research of a major international pharmaceutical company’s breakthrough Immuno-oncology Resisted participants profiling.
- Provided a wide range of expert witness services to several biotechnology and major pharmaceutical companies to model, analyze, develop solutions and clinical trial development related issues.
Bioinformatics Research Associate
MADRAS DIABETES RESEARCH FOUNDATION
Chennai
05.2019 - 03.2022
- Strong experience in NIHR INSPIRED project development and coordination, strategic planning, and grant writing Ability to contribute important unique ideas pertaining to the planning, development, modification, and execution of new case studies.
- Developed complex mappings in DataStage to load the data from various sources into Data Warehouse, using different transformations stages like Joiner, Transformer, and Aggregator.
- Implemented ETL components in data marts based on the filter rules to obtain needed data from different source systems for calculating required metrics.
- Tuned SQL queries and performed refinement of the database design leading to significant improvement in system response time and efficiency Expertise in RDBMS, Normalization, data handling, and data wrangling techniques for data discovery, data cleaning, and structuring.
- Building stored procedures involving complex joins, subqueries, aggregate functions, User-defined functions in R, Python, and SQL for a variety of business requirements
- Documented user case requirements, translated requirements into system solutions, and develop an implementation plan and schedule Loaded data from flat data files into SQL Server database tables using bulk insert, and table import
- Responsible for workflow, productivity, and the overall management and monitoring of the Electronic Medical Record Database with the main goal to achieve the highest level of quality inpatient care data for analysis.
Education
Master of Science - Medical Biotechnology
Chettinad Academy of Research And Education
Chennai, TN 01.2017 - 01.2019
Bachelor of Science - Advanced Zoology & Biotechnology
Loyola CollegeAffiliated To Madras University
Chennai, TN 01.2013 - 01.2016
Skills
R-Programming
SQL server 2012
Exploratory Data Analysis
GATK pipeline
WGCNA
Accomplishments
- Bioinformatics for Biologists: An Introduction to Linux, Bash Scripting, and R issued by Future Learnon May 2021
- Genetics and next generation sequencing for Bioinformatics issued by Udemy on February 2021
- Machine Learning A-Z: Hands-On Python & R In Data Science issued by Udemy on December 2020
- R programming A-Z: R For Data Science issued by Udemy on October 2020
computational skills
- Omics Data Analysis - High integrity data's (genomics, proteomics & metabolomics) exploration using standard
computational models, databases and evaluating them for clinical studies like Next generation sequencing (NGS) Genome Assembly - BWA, Bowtie2, Hisat2 Annotation - SAMtools, BAMtools Variant calling - GATK, bcftools and whole genome sequencing (WGS).
- Pipeline Development – Routine Standard models implementation for etiological studies (phenotype &
genotype) data acquisition process such as (mining, cleansing, analyzing & visualization).
- High Performance Computing - Handled large data resources for protein models, molecular docking studies
and molecular dynamics in computational workstation ( Dell Precision T3610) model and Identification of genetic
variants and gene functional enrichment analysis using Lenovo ThinkPad P52 workstation with Linux platform.
Publications
- Ahmed SSSJ, Paramasivam P, Kamal Raj, Vishal Kumar, Murugesan R and Ramakrishnan V (2020) “Regulatory Cross Talk Between SARS-CoV-2 Receptor Binding and Replication Machinery in the Human Host”. Front. Physiol. 11:802. doi: 10.3389/fphys.2020.00802.
- Kamalraj N, Sathishkumar M, Arunvignesh M, Baskar V, Jebarani S, Amutha A, Deepa M,et.el. Retrospective analysis (2009-2017) of factors associated with progression and regression of non- alcoholic fatty liver disease (Hepatic steatosis) in patients with type 2 diabetes seen at a tertiary diabetes centre in Southern India. Diabetes Metab Syndr. 2021 Sep-Oct;15(5):102261. doi: 10.1016/j.dsx.2021.102261. Epub 2021 Aug 25. PMID: 34464909.
- Anjana RM, Siddiqui MK, Jebarani S, Vignesh MA, Kamal Raj N, Unnikrishnan R, Pradeepa R,et.el. Prescribing Patterns and Response to Antihyperglycemic Agents Among Novel Clusters of Type 2 Diabetes in Asian Indians. Diabetes Technol Ther. 2022 Jan 5. doi: 10.1089/dia.2021.0277. Epub ahead of print. PMID: 34609928.
- Rajendra Pradeepa, Lal Shreya, Ranjit Mohan Anjana, Saravanan Jebarani, Nithyanantham Kamal Raj, Madhan Srinivasan Kumar, Parthasarathy Jayaganesh, Onkar C. Swami, Viswanathan Mohan, Frequency of iron deficiency anemia in type 2 diabetes - Insights from tertiary diabetes care centres across India, Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Volume 16, Issue 11. PMID: 36343394
Timeline
SENIOR BIOINFORMATICIAN
ZS ASSOCIATES
04.2022 - Current
Bioinformatics Research Associate
MADRAS DIABETES RESEARCH FOUNDATION
05.2019 - 03.2022
Master of Science - Medical Biotechnology
Chettinad Academy of Research And Education
01.2017 - 01.2019
Bachelor of Science - Advanced Zoology & Biotechnology
Loyola CollegeAffiliated To Madras University
01.2013 - 01.2016