Summary
Overview
Work History
Education
Skills
Academic Projects
Publications
Languages
Timeline
Generic

Madhushree Rao

Bengaluru

Summary

R&D professional with hands-on experience in formulation development and optimization, analytical characterization, and early-stage drug discovery. Proficient in designing experiments, executing biological assays, and conducting stability studies. Strong foundation in nanotechnology-based drug delivery platforms, skilled in data interpretation, regulatory documentation, troubleshooting experiments, and collaborating effectively with cross-functional teams.

Overview

5
5
years of professional experience

Work History

Formulation Scientist

POPVAX Pvt. Ltd.
Hyderabad
06.2024 - 08.2025
  • Designed and optimized lipid nanoparticle formulations for mRNA therapeutics and vaccines using microfluidic technologies.
  • Conducted particle characterization (size, PDI, zeta), and encapsulation efficiency (Ribogreen) to assess functional mRNA delivery.
  • Supported mRNA pre-formulation and stability strategy through buffer screening, lipid composition assessment, and FRR/TFR optimization.
  • Executed short-term, accelerated, freeze thaw stability studies, evaluating robustness under logistics-simulated stress and cold-chain variations.
  • Performed process development and scale-up activities, optimizing critical parameters to ensure consistency, reproducibility, and suitability for GMP.
  • Interpreted formulation data using physicochemical, lipid headgroup chemistry, and ionizable lipid pKa, contributing to data-driven decision-making.

Research Assistant

Vriksha Vijnan Pvt. Ltd.
Bengaluru
12.2020 - 07.2022
  • Led pharmacognostic evaluation and quality control testing for AYUSH-approved herbal formulations in accordance with pharmacopeia's standards.
  • Worked on phytochemical extractions, screening, HPTLC fingerprinting, and qualitative/quantitative profiling to identify and confirm active phytoconstituents.
  • Carried out microbiological evaluations, including antimicrobial assays and antioxidant assays, to assess product safety and functional characterization of herbal extracts.
  • Contributed to literature reviews, manuscript preparation, and research publications by compiling, analyzing, and interpreting experimental data.
  • Trained and mentored interns in laboratory techniques, analytical procedures, and workflows.

Education

Master of Technology - Nanoscience And Technology

Defence Institute of Advanced Technology (DRDO)
Pune
09-2024

B.E. - Biotechnology

Dayananda Sagar College of Engineering
Bengaluru
04-2019

Skills

  • Formulation development
  • Biological assays
  • Microfluidic technologies
  • Particle characterization
  • Analytical skills
  • Regulatory documentation
  • Bioinformatics tools and databases
  • Process development
  • Antimicrobial evaluation
  • Data analysis
  • Team collaboration
  • Troubleshooting
  • Training and mentoring
  • Problem solving
  • Effective communication

Academic Projects

Indian Institute of Technology, Hyderabad, IIT-H (2023-2024)

Chitosan nano-emulsion for enhanced oral bioavailability of phytochemical

  • Formulated and optimized nanoemulsions for oral delivery, undertook particle size, zeta potential, encapsulation efficiency, and TGA analysis, and implemented in vitro dissolution testing and stability studies to evaluate formulation performance

Centre for Incubation, Innovation, Research, and Consultancy (2018)

Hemostatic sponge for rapid blood absorption

  • Developed graphene oxide (GO) nanoparticles and characterized them via FTIR, UV-Vis, XRD, and SEM, engineered GO sponges cross-linked with chitosan and aloe vera to enhance structural properties, evaluated GO sponges for absorption behavior, and initiated cytotoxicity studies to assess biocompatibility

Publications

Rao, M. M. V., et al. (2024). Silver nanoparticles for food technology: A review of hybrid advances

Rao, M. M. V., et al. (2023). Bioinformatics Tools for Discovery of Potential Anti-diabetic Drugs from Lichens. Computational approaches in biomaterials, bioinformatics, and biomedical engineering applications

Rao, M. M. et al. (2022) Plectin as a putative novel biomarker for breast cancer: an in silico study, network modeling analysis in health informatics, and bioinformatics

Rao, M. M. V., & Hariprasad, T. P. N. (2021). In silico analysis of erythrin against therapeutic targets of diabetes, in silico pharmacology

Languages

English
Proficient (C2)
C2
Hindi
Advanced (C1)
C1
kannada
Native
Native

Timeline

Formulation Scientist

POPVAX Pvt. Ltd.
06.2024 - 08.2025

Research Assistant

Vriksha Vijnan Pvt. Ltd.
12.2020 - 07.2022

Master of Technology - Nanoscience And Technology

Defence Institute of Advanced Technology (DRDO)

B.E. - Biotechnology

Dayananda Sagar College of Engineering
Madhushree Rao