MANDAPATI Venkata Surya Narasimha Varma
Pharma And Fine Chemicals Manufacturing .
Visakhapatnam,AP
Summary
Experienced professional with 35+ years in Production and Quality Assurance, currently Plant Head at GPR Life Sciences Pvt Limited. Skilled in strategic planning, communication, and coordination to lead teams effectively. Proven track record in establishing quality systems to reduce waste and enhance the company's reputation. Proficient in coordinating technology, machinery, equipment, process methodology, and quality control enhancements. Extensive experience in conducting customer audits for pharmaceutical companies and regulatory audits for international bodies. Proficient in implementing facility modifications for operational efficiency and industry standards compliance.
Overview
36
36
years of professional experience
1989
1989
years of post-secondary education
3
3
Languages
Work History
Plant Head
GPR Life Sciences Pvt Limited
12.2023 - Current
- Efficiently gained manufacturing experience in Metformin Hydro Chloride API of IP/USP/BP.
- Audits faced Drug Control Audit by KDIL, AKUMS PHARMA LTD.
- Reduced downtime by establishing a preventative maintenance program for all equipment.
- Increased productivity, optimizing labor allocation, and scheduling across multiple shifts.
- Managed staff training programs to ensure employees were skilled in the latest industry practices and safety requirements.
- Enhanced safety standards with thorough risk assessments and implementing necessary protocols.
Sr. Manager Production
Ocimum Labs Pvt Ltd
09.2022 - Current
- Efficiently gained manufacturing experience in 1-Methyl-5-toluoyl pyrrole-2-acetamidoacetic acid, 1-Methyl-5-P-toluoyl Pyrrole-2-acetic Acid (TOLEMETIN), Ethyl 4-(2-Hydroxypropan-2yl)-2-propyl-1H Imidazole-5-carboxylate, 5-Methoxy-1-[4-(Trifluoromethyl) penyl] pentan-i-one, 3-Methylflavone-8-Carboxylic Acid, 2-(2 Amino-5-bromo benzoyl) pyridine, 4-Chloro-7H-pyrrolo[2,3-d] pyrimidine.
- Audits faced Ami Life Science Japan & Dr.Reddys, ZCL Chemicals Ltd.
Sr. Manager Production
GMFC Labs Pvt Ltd
11.2019 - 08.2022
- Efficiently gained manufacturing experience in API of Flurbiprofen, special Intermediates of 2-(((2-((Dimethylamino) methyl) thiazol-4-l) methyl) thio) ethanamine, 2,3-Dichlorobenzoic Acid, Benzene Sulfonic Acid 3, 3-Dithiobis Diso Salt, Diisopropyl azodicarboxylate, Diethyl Azodicarboxylate, 6-(4-Hydroxy phenoxy) hexyl 2-propenoate, 2,2-dimethylmalonic acid, Lawesson's Reagent, Benzamide, Tetrazole.
- Audits faced E Sai Life Sciences Ltd Japan, Syngene, Divis Laboratories Ltd.
Production Manager
Everest Organics Limited
01.2018 - 11.2019
- Efficiently gained manufacturing experience in Active Pharma Ingredients of Pantoprazole Sodium Sesquihydrate, Dex Lansoprazole.
Production Manager
Hetero Labs Limited
10.2001 - 01.2018
- Efficiently gained manufacturing experience in Active Pharma Ingredients of Sparfloxacin, Valsartan, Irbesartan, Losartan Potassium, etoricoxib, Oseltamivir, Clopidogrel Hydrogen Sulphate, Nevirapine, Lamivudine and Zidovudine.
- Proactively adapted and implemented the selection of equipment in new projects & new products scale up with HAZOP study.
- Conducted the trouble shooting in % of yield improvements and identified & improved the loss identification.
- Performed capacity enhancement with minimum investment and performed time cycle reduction in distillation, drying & enhancement of productivity.
- Successfully coordinated with vendors for adopting of new technology for enhancement of productivity & operational convenience & Energy conservation.
- Achieved reduction in effluent generation and water consumption, material, and energy balance.
Production Executive
Medicorp Technologies India Ltd.
04.1996 - 09.2001
- Successfully scaled up the product Fluconazole, Alprazolam, Cetirizine Dihydrochloride and Acyclovir from pilot plant to commercial production.
- From 1999 to 2001 worked in Quality Assurance for 1st FDA Audit facing for Acyclovir.
- Proficiently upgraded ISO documents 9001:2000 versions from ISO 9000:1994 version.
- Completed course in the Internal Quality Audit System from Center for Electronics Test Engineering through Medicorp Technologies India limited.
- Faced several customer audits including Cipla, Ranbaxy, Novartis, and US FDA.
Shift In-charge
Parsin Chemicals Ltd.
04.1991 - 03.1996
- Company Overview: (100% Export Oriented Unit)
- For manufacturing Sodium Azide fine chemicals.
- (100% Export Oriented Unit)
Production Chemist
Plant Organics Limited
06.1989 - 03.1991
- For manufacturing Sulfamethoxazole, Ibuprofen.
Education
B.Sc. - Chemistry, Math’s & Physics
Andhra University
Diploma in Total Quality management - undefined
Quality Professionals Group
ISO 9001-2015 (Quality), ISO14001-2015 (Environmental Management System), ISO 18001-2007 (OSHAS) & ISO 50001-2011 (Energy Management System) - undefined
Hetero Labs Ltd.
SAP Production Planning Implementation - undefined
Medicorp & Hetero Labs Ltd.
Skills
Pharma Production Management
Third Party Audits
Quality Management Systems Implementation
Process Improvements
Waste minimization
Calibration/ Validations
Operations management
Quality Systems/ SOPs
Health and safety compliance
Training & Development
Production scheduling
Cross Functional Coordination
ISO standards
Customer Communication & Complaints Handling
Cost reduction
Locations
- Humnabad, Humnabad, Karnataka
- Atchutapuram, Atchutapuram
- Sadasivapeta, Sadasivapeta
- Nakkapally, Nakkapally, Andhra Pradesh
Personal Information
Date of Birth: 03/01/69
Key Result Areas
- Managing all the production activities of the Plant which include manufacturing of API & Intermediates.
- Reviewing the daily Productivity and ensuring the Implementation of cGMP in the Plant with compliance to company SOP’s and regulatory guidelines.
- Identifying and troubleshooting product problems by gradual process optimization and maximum utilization of machines speed.
- Developing new customer for third party products manufacturing along with finalizing the commercial as well as technical aspects.
- Ensuring good housekeeping and safely health and environment standards.
- Preparing SOP, maintaining documents as per GMP. Review, Change and Distribution of Standard Operating Procedures (SOP’s), Specifications and Quality Formats.
- Ensuring Environmental conditions to be maintained in respective area of the operation.
Timeline
Plant Head
GPR Life Sciences Pvt Limited
12.2023 - Current
Sr. Manager Production
Ocimum Labs Pvt Ltd
09.2022 - Current
Sr. Manager Production
GMFC Labs Pvt Ltd
11.2019 - 08.2022
Production Manager
Everest Organics Limited
01.2018 - 11.2019
Production Manager
Hetero Labs Limited
10.2001 - 01.2018
Production Executive
Medicorp Technologies India Ltd.
04.1996 - 09.2001
Shift In-charge
Parsin Chemicals Ltd.
04.1991 - 03.1996
Production Chemist
Plant Organics Limited
06.1989 - 03.1991
Diploma in Total Quality management - undefined
Quality Professionals Group
ISO 9001-2015 (Quality), ISO14001-2015 (Environmental Management System), ISO 18001-2007 (OSHAS) & ISO 50001-2011 (Energy Management System) - undefined
Hetero Labs Ltd.
SAP Production Planning Implementation - undefined
Medicorp & Hetero Labs Ltd.
B.Sc. - Chemistry, Math’s & Physics
Andhra University