A dedicated professional with a Master's degree in Biotechnology and extensive experience in toxicity research. Proficient in advanced molecular biology techniques including gene cloning, PCR, DNA/RNA sequencing, and nanoparticle impact assessment on biological systems. Well-versed in zebrafish research methodologies and adept in laboratory administration. Demonstrated expertise in research design, precise data collection, and rigorous analysis, ensuring accuracy and safety in scientific investigations. I am highly proficient in Microsoft Office Suite, with extensive experience in using Word, Excel, PowerPoint, and Outlook for various professional tasks
Characterization and Zebrafish - based Screening of Commercially Available AI203 for Biomedical Applications, 12/2023, 05/2024, In order to evaluate the toxicity and biocompatibility of commercially available aluminum oxide (Al2O3) nanoparticles, I conducted study using zebrafish embryos. Taking into account their distinct physicochemical characteristics, our study sought to ascertain their appropriateness for biomedical applications. In order to determine the lethal concentration 50 (LC50), evaluate developmental toxicity, and pinpoint potential teratogenic consequences, we subjected the embryos to various concentrations of Al2O3 nanoparticles. Our research showed concentration-dependent toxicity, with larger doses leading to notable death and developmental defects. Morphological abnormalities and oxidative stress were induced even at sub-lethal levels. Although aluminum oxide nanoparticles have great potential in biomedicine, more thorough biocompatibility studies are required due to the critical need to carefully evaluate their safety profile before utilizing them in clinical settings.