MOHAMMAD YASEEN ABBASI

Clinical pharmacologist and pharmacometrics scientist with PharmD and PhD, complemented by postdoctoral training in clinical pharmacology. Expertise in population pharmacokinetics, pharmacokinetic/pharmacodynamic modeling, and physiologically based pharmacokinetic modeling. Research includes optimizing drug therapy in diverse populations, with significant contributions to studies on preterm neonates and critically ill patients. Active in international collaborations, with numerous publications in leading journals and a focus on advancing precision medicine and rational drug use.

• HMX – Harvard Medical School Pro Immunology—Immuno-oncology Certificate of Achievement.
• Population Pharmacokinetics and PBPK courses organized in collaboration of IUSM and METRUM Research Group at Indianapolis in 2022.
• PBPK courses and Workshop for firsthand “MRGSOLVE” R package organized by METRUM Research Group, Eli Lilly and IUSM at Indianapolis in 2022.
• 11th Annual Meeting of NICHD and NICHD-NIGMS T32 Trainees in Pediatric Clinical Pharmacology on 09/19/22 - 09/20/22.
• Certara University PBPK certification courses Intensive 10 days Online Workshop on Model informed Drug Development in 2022.
• Certara University PBPK certification courses Intensive 3 days Special Populations Online Focused Workshop in 2022.
• Pharmacometrics School: Modeling Using Monolix Suite virtual course in 2021.

• Defining infant daily dose and relative infant daily dose using Lactation PBPK Model., Abbasi M.Y, Robert R Bies, Sara K Quinney., manuscript
• Pharmacometrics Modeling of Opioid Disposition in Pregnancy: A Systematic Review of PopPK and PBPK Approaches, Model Limitations, and Future Directions., Zaidi SS, Abbasi MY, Ganapaneni S, Quinney SK., manuscript in communication
• Pharmacotherapy research landscape and knowledge gaps of opioids in maternal and pediatric populations., Shendre, A., Liu, X., Chiang, C., Goodwin, A., Oteng, S. R., Deypalubos, J. A. F., Zhang, S., Wang, L., Liu, J., Abbasi, M. Y., Aruldhas, B. W., Zaidi, S. S., Kirkpatrick, L. M., Silva, L. D., Overholser, B. R., O'Kane, A. M., Kannankeril, P. J., Patrick, S. W., Wiese, A. D., Quinney, S. K., … Li, L., Pharmacotherapy, 45, 6, 367–385, 06/2025, https://doi.org/10.1002/phar.70024
• Recommendations of Gentamicin Dose Based on Different Pharmacokinetic/Pharmacynamic Targets for Intensive Care Adult Patients: A Redefining Approach., Abbasi, M. Y., Chaijamorn, W., Wiwattanawongsa, K., Charoensareerat, T., & Doungngern, T., Clinical pharmacology: advances and applications, 15, 67–76, 2023
• What is the right gentamicin dose for multiple trauma patients? A Monte Carlo simulation exploration study., Abbasi, M. Y., Wiwattanawongsa, K., Chaijamorn, W., Charoensareerat, T., & Doungngern, T., International journal of critical illness and injury science, 13, 3, 118–124, 2023
• The MPRINT Hub Data, Model, Knowledge, and Research Coordination Center: Bridging the gap in maternal-pediatric therapeutics research through data integration and pharmacometrics., Quinney, S. K., Bies, R. R., Grannis, S. J., Bartlet, C. W., Mendonca, E., Rogerson, C. M., Backes, C. H., Shah, D. K., Tillman, E. M., Costanne, M. M., Aruldhas, B. W., Allam, R., Grant, A., Abbasi, M. Y., Kandasamy, M., Zang, Y., Wang, L., Shendre, A., & Li, L., Pharmacotherapy, 2023, 10.1002/phar.2765
• The Impact of Low Cardiac Output on Propofol Pharmacokinetics across Age Groups-An Investigation Using Physiologically Based Pharmacokinetic Modelling., Allegaert K, Abbasi M.Y., Michelet R, Olafuyi O., Pharmaceutics, 14, 9, 1957, 09/2022
• Current, and future physiologically based pharmacokinetic (PBPK) modeling approaches to optimize pharmacotherapy in preterm neonates., Allegaert K, Abbasi, M.Y., Annaert P, Olafuyi O., Expert Opin Drug Metab Toxicol, 18, 5, 301-312, 2022
• Physiologically based pharmacokinetic modelling of acetaminophen in preterm neonates-The impact of metabolizing enzyme ontogeny and reduced cardiac output., Olafuyi O, Abbasi MY, Allegaert K., Biopharm Drug Dispos, 42, 9, 401-417, 2021
• Population Pharmacokinetics and Dose Optimization of Vancomycin in Critically Ill Children., Sridharan, K., Abbasi, M.Y., & Mulubwa, M., Eur J Drug Metab Pharmacokinetic, 46, 539–546, 2021
• Alzheimer’s disease Management: current therapy and recent drug development., Abbasi M.Y., MD Shamshir Alam., International Neuropsychiatric Disease Journal, 7, 2, 119, 2016
• Plasma homocysteine: a diagnostic marker in various disorders., MD Shamshir Alam, Mohammad Zameer, Abbasi, M.Y., Wjpps, 5, 1, 103-120, 2016
• A prospective study on prescribing patterns of antidiabetic drugs., Abbasi M.Y., Ali MA., World Journal of Pharmacy and Pharmaceutical Sciences, 3, 5, 4557, 2014
• Prescribing pattern of drugs in stroke patients: A prospective study., Abbasi M.Y., Ali MA., Archives of Pharmacy Practice, 3, 283-8, 2012

• Modeling Peripheral Cytokine Dynamics Following Bispecific Dosing in Solid Tumors, Indiana Clinical and Translational Sciences Institute (CTSI) 12th Annual Symposium on Disease and Therapeutic Response Modeling and Simulation, 02/22/23 - 02/24/23
• Automated Population PK model selection with Pirana, Indiana Clinical and Translational Sciences Institute (CTSI) 12th Annual Symposium on Disease and Therapeutic Response Modeling and Simulation, 02/22/23 - 02/24/23
• Use of Paral Area Under Curve (pAUC) for Ensuring Therapeutic Equivalence, ASCPT Career Development Committee and the Life Cycle Management (LCM) Community, 10/2022, https://vimeo.com/764957977/3a42912153
• Towards Development of Predictive PBPK Models for Biologics, Indiana Clinical and Translational Sciences Institute (CTSI) 11th Annual Symposium on Disease and Therapeutic Response Modeling and Simulation, 02/16/22 - 02/18/22
• Increasing the efficiency of development of neutralizing monoclonal antibodies for the treatment of COVID-19 through PKPD modeling and simulation, Indiana Clinical and Translational Sciences Institute (CTSI) 11th Annual Symposium on Disease and Therapeutic Response Modeling and Simulation, 02/16/22 - 02/18/22

• The Scholarship Awards for Master and Ph.D. Studies, Thailand's Education Hub for ASEAN Countries (TEH-AC), 2017
• Grant to conduct study of Pharmacokinetics of gentamicin in Multiple Trauma Patients with Open fractures, Prince of Songkhla University, 2019
• Granted Fellowship in Clinical Pharmacology, Division of Clinical Pharmacology, Department of Medicine, 2023, Indiana University School of Medicine, Indian, USA
• Received an Academic-Industrial join Postdoctoral Research Fellowship, 2022 and 2024, Indiana University School of Medicine, Indianapolis, IN and Northeastern University, Boston MA

• American Society of Clinical Pharmacology and therapeutics (ASCPT)
• International Society of Pharmacometrics (ISoP)
• License Pharmacist in India
• License Pharmacist Saudi Arabia

• Clinical Pharmacology, Pharmacokinetics (PK), Pharmacodynamics (PD), and Pharmacometrics
• Population PK, PBPK Modeling, and Model-Informed Precision Dosing (MIPD)
• Quantitative Modeling & Simulation and Exposure–Response Analysis
• Pharmacometric Software: NONMEM, MonolixSuite, PKanalix, WinNonlin, R, Python
• Non-Compartmental Analysis (NCA) and Dose Optimization
• Clinical Trial Simulation and Population Modeling
• Research-Led Teaching, Curriculum Development, and Assessment Design
• Postgraduate Student Supervision and Academic Mentorship
• Interdisciplinary Research in Pediatrics, Transplantation, Critical Care, and Infectious Diseases
• Pharmacoepidemiology, Medication-Use Evaluation, and Real-World Evidence Research
• Scientific Communication, Teamwork, and Multicultural Collaboration

• Review of Population Pharmacokinetic (PopPK) Studies of Opioids in Maternal and Pediatric Populations, Fourteenth American Conference on Pharmacometrics (ACoP14), 11/05/23 - 11/08/23, National Harbor, Maryland, USA
• Lactation PBPK Model for Gabapentin, 2nd Annual MPRINT Hub Meeting and Scientific Symposium, 04/18/23 - 04/21/23, UCSD La Jolla, CA
• Review of population pharmacokinetic studies of opioids in maternal & pediatric populations, Indiana Clinical and Translational Sciences Institute (CTSI) 12th Annual Symposium on Disease and Therapeutic Response Modeling and Simulation, 02/22/23 - 02/24/23
• A structured search on physiology-based pharmacokinetic modelling reports in preterm neonates: growing science., ESDPPP Congress Liverpool, 2022
• Clinical pharmacy education System, Istanbul Medipol University, 2015
• The comparative study for monotherapy and dual therapy of hypoglycemic agents in diabetes individuals, 4th Medical Research Day-Updates in Diabetes Mellitus, 2014, Jazan University, KSA
• The Prescribing Pattern of Drugs in Stroke Patients: A Super Specialty Hospital Based Study, Indian Pharmaceutical Association Convention, 2012, Manipal University, India
• Study on Prescribing Patterns of Anti Diabetic drugs, Indian Pharmaceutical Association Convention, 2012, Manipal University, India
• Use of robotics system in Hospital Pharmacy: Equipped with Next Generation Pharmacist, Indian Pharmaceutical Association Student Congress, 2012, Warangal, India

• Pharmacist - Pharmacy Council of India
• Pharmacist - Saudi Commission for Health Specialties (SCFHS)
• Clinical Pharmacology Fellowship - Indiana University School of Medicine

• The Scholarship Awards for Master’s and Ph.D. Studies, Thailand's Education Hub for ASEAN Countries (TEH-AC), 2017.

• American Society of Clinical Pharmacology and Therapeutics (ASCPT)
• International Society of Pharmacometrics (ISoP)