Nagesh Kancharla
Mumbai
Summary
Plant Molecular Breeder, Synthetic Biologist & People Manager. Detail-oriented team player with strong organizational skills. Ability to handle multiple projects simultaneously with a high degree of accuracy.
Overview
18
18
years of professional experience
Work History
Senior Molecular Breeder
Reliance Industries Limited
04.2014 - Current
- Established molecular breeding platform for crop improvement through genome selection (WGP), and genome-wide association studies
- Identified QTLs and genes through genome mapping and trait introgression for disease resistance in crops.
- Successfully established phenotyping facilities for field crops. Managed and coordinated three research sites for crop improvement
- Supervision and coordination with genomics team for gene discovery & characterization
- Co-ordinate breeding and trait technology teams for implementing genomic strategies in crops
- Successfully implemented genome editing strategies through CRISPR in food crops & Vegetables
- Skilled at working independently and collaboratively in a team environment. Proven ability to learn quickly and adapt to new situations. Worked effectively in fast-paced environments.
Molecular Breeder
Corteva Agriscience
08.2008 - 01.2014
- Developed mapping populations and established genotyping, phenotyping facilities for identifying, fine-mapping novel Brown Plant Hopper (BPH), and bacterial leaf blight resistance genes in rice
- Successfully Implemented Marker Assisted Breeding for disease resistance in rice, and corn
- Completed over 20 million data points through high-throughput Single Nucleotide Polymorphism genotyping for corn mapping populations
- Implemented statistical analysis, data management, work documentation in ELN & PRISM for field experiments
- Established drought & triple stress assay, high throughput gene cloning, transformations & mutational screening in Arabidopsis
- Optimized high through-put imaging using Lemnatec for observing drought & triple stress tolerance in Arabidopsis.
Breeder
Mahyco Research Foundation
04.2005 - 01.2008
- Developed various mapping populations in rice through backcross and pedigree methods for rice blast resistance
- Established genotyping and phenotyping facilities for biotic and abiotic traits screening in rice
- Successfully collected and characterized rice blight & rice blast infected samples from all over India
- Implemented QTL mapping in recombinant inbred lines for rice blast resistance
- Involved in hybrid rice: trait integration, seed production and identifying new restorer and maintainer lines
- Instructor for University graduates and breeders for Marker Assisted Selection in crops.
Education
Ph.D. - Plant Genetics
04.2016
QTL Mapping in Oryza sativa for Rice Blast Disease
Master of Technology - Biotechnology
03.2005
Master of Science - Microbiology
2002
Bachelor of Science - Microbiology, Botany & Chemistry
2000
Skills
- Breeder with over 16 years of experience in the field of Plant molecular breeding, synthetic biology, andgenome editing
- People management skills Excellent research skills to consistently deliver products on time and within budgets and specifications
- Outstanding organizational and communication abilities Adept at Leading research and development teams in plant molecular and synthetic biology
Accomplishments
1) Kancharla Nagesh, Dhananjay Dhokane, Anindya Bandyopadhyay. Genome editing in Chlamydomonas reinhardtii Using Cas9-gRNA Ribonucleoprotein complex: A step-by-step guide. Springer-Nature, 2023.
2) Kancharla Nagesh, Anindya Bandyopadhyay, Santanu Dasgupta. Elsevier book chapter, 2022. Covid based assays for rapid detection of SARS—CoV-2. Omics approaches and technologies in Covid-19.
3) Kancharla Nagesh, Vijay Yepuri. Molecular Biology Reports, 2022. Genotyping by sequencing-based linkage map construction and identification of quantitative trait loci for yield related traits and oil content in Jatropha (Jatropha curcas L.). IF 2.742
4) Kancharla Nagesh, Arockiasamy Savarimuthu. Oil Crop Science 6, 2021 180–191. Breeding and biotechnological efforts in Jatropha curcas L. for sustainable yields.
5) Kancharla Nagesh, Anindya Bandyopadhyay, Thomas P Brutnell. Frontiers in Plant Science, October 2020: CRISPR-Cas12a (Cas12a): a versatile tool in the plant genome editing toolbox for agricultural advancement. IF 6.627
6) Kancharla Nagesh, Vivek S. Javalkote, Anindya Bandyopadhyay and Santanu Dasgupta. Methods, October 2020. CRISPR-based assays for rapid detection of SARS-CoV-2. IF 4.647
7) Kancharla Nagesh, Vijay Yepuri. Springer nature- Molecular Reports, June 2020. Development of genome wide transposable elements based repeat junction markers in Jatropha (Jatropha curcas L.) IF 2.742.
8) Kancharla Nagesh, Saakshi Jalali, V B Reddy. Springer-3Biotech 2019: Exploitation of Hi-C sequencing for Improvement of genome assembly and in- vitro validation of differentially expressing genes in Jatropha curcas L. IF 3.446
9) Kancharla Nagesh, Saakshi Jalali. Genes 2019: Denovo sequencing and hybrid assembly of biofuel crop Jatropha curcas L: Insights on gene annotation, comparative genomics and transcriptome analysis with identification of quantitative trait loci (QTLs) for geminivirus resistance. IF 4.141
10) Kancharla Nagesh, Saakshi Jalali. Whole genome sequences & transcriptome sequences of Jatropha curcas L. submitted to NCBI 2018.
11) Kancharla Nagesh, Saakshi Jalali. International Journal of Pure and Applied Biosciences 2018: Influence of genetic and molecular markers in evaluation of Jatropha diversity.
12) Kancharla Nagesh, Kalmeshwar, mohan, Plant Breeding 2012: Marker-assisted pyramiding of Pi-1 and Pi-2 genes imparting resistance to rice blast into PRR78, restorer line of Pusa RH-10 Basmati rice hybrid. IF 2.536
13) Kancharla Nagesh, Thippeswamy Sanka, and C S Reddy. The 4th International Rice Blast Conference, China October 9-14, 2007: Validation of Linked Molecular Markers for Effective Blast Resistance Genes in Rice.
14) Kancharla Nagesh, Thippeswamy. S, & C. S. Reddy, 2006: Identification of effective blast resistance genes and validation of linked molecular markers in rice. In the proceedings of the International Symposium on Frontiers in Genetics and Biotechnology- Retrospect and Prospect, Osmania University from January 8th - 10th, 2006.
Oral Presentations
1) Kancharla Nagesh, Oral presentation at NGBT, Mumbai, Sep 30 to 2nd Oct 2019 on Jatropha Genomics and its importance as Bio-fuel crop.
2) Kancharla Nagesh, Oral Presentation at 3rd World Plant Genomics and Plant Science Congress: July 15- 16, 2019, Osaka Japan: Importance of Jatropha as Bio- fuel crop.
Timeline
Senior Molecular Breeder - Reliance Industries Limited
04.2014 - Current
Molecular Breeder - Corteva Agriscience
08.2008 - 01.2014
Breeder - Mahyco Research Foundation
04.2005 - 01.2008
Osmania University - Ph.D., Plant Genetics
Jawaharlal Nehru Technological University - Master of Technology, Biotechnology
Kakatiya University - Master of Science, Microbiology
Kakatiya University - Bachelor of Science, Microbiology, Botany &
Chemistry
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