Nausheen Khan

Motivated and dedicated professional focused on enhancing educational and career skills in stable, dynamic environments. Possesses strong analytical abilities and technical knowledge, excelling in data-driven settings. Approaches challenges with a positive attitude and determination to achieve results.

Project title: "Conception, development, and characterization of a novel topical formulation for the treatment of plaque psoriasis" The objective of the study project was to develop a new topical delivery system in order to provide the loco-regional release of fixed-dose combination drugs: Vit-D analogue and corticosteroids into the skin, and to reduce the systemic absorption and side effects of the drugs The drugs used in the combination in order to have a synergistic effect and acting from two different mode of actions. The ingredients were screened and selected after optimal results. FDC drugs loaded poly (D,Lactic coglycolic acid) PLGA micro particles were prepared by solvent evaporation technique. The analytical methods- UV and HPLC was developed for analysis of drugs. Particle size analysis and morphological characterization was done by Optical microscopy, SEM, FTIR, DSC. In addition project also involved the development of novel modern base "Bigel" using some specific natural ingredients and edible oils indicated in the Unani and Ayurvedic system of medicine for the treatment of plaque psoriasis. The developed topical formulation base was tested for Physical evaluation (color, odor, texture, phase separation, oil leakage), rheological parameters and texture analysis (hardness, stickiness and cohesiveness) through Optical Microscopy, Homogenizer, Freeze thaw procedure, Texture analyzer, Rheometer etc in order to obtain the best optimized Bigel base. The in-vitro drug release and permeability of the final topical formulation was accessed through confocal microscopy using guinea pig skin. The final formulation comprising FDC drugs loaded PLGA micro particles in Bigel base was subjected to animal studies for amelioration of Psoriasis symptoms and results were compared with the marketed formulation.

• Received a certificate of merit for second position from the Delhi Pharmacy Council
• Received the Quick Impact Award from ZS Associates within the first year
• GPAT 2016 qualified
• Successfully completed the course on intellectual property rights conducted by Ennoble IP at Jamia Hamdard
• Attended a national conference by the Ministry of Chemicals and Fertilizers titled 'Pharmaceutical Analysis Techniques and Quality by Design'
• Attended a national seminar on pharmaceutical performance using ICH Q10 guidelines
• Attended a seminar on pharmacovigilance by Moin Don, CEO of PVCON

• Contributed as the second author in the following chapters of the published book titled 'Fingerprinting Techniques in Food Authentication and Traceability,' edited by K.S. Siddiqui, Leo M.L. Nollet, CRC Press (Taylor and Francis Group)
• Chapter 8: Introduction to food authentication based on fingerprinting techniques, Authors: Md Rizwanullah, Nausheen Khan, Saima Amin, Javed Ahmed
• Chapter 9: Introduction to food traceability based on fingerprinting techniques, Authors: Md Rizwanullah, Nausheen Khan, Saima Amin, Javed Ahmed

• CPHI India 2019 at Greater Noida, UP (attended session on 'China drug registration process' and 'major reforms in China drug regulatory system')
• CPHI Frankfurt 2019 in Germany (attended session on 'Korean biopharmaceutical and North African drug market')
• Iran Pharma Expo 2019 in Tehran, Iran
• CPHI MEA event 2018 at Abu Dhabi, UAE
• IPHEX 2018 event at Pragati Maidan, India

• Date of birth: 07/10/1992
• Status: Married
• Current address: Flat No. 101, Hewo Apartments, Sector 31, Gurgaon, Haryana
• Hobbies: Traveling, playing badminton, outdoor games, and listening to music

• Zeenat Iqbal, Associate Professor, Jamia Hamdard
• Nagesh Ghanshala, Country Head, Jakob and Partners
• Puneet Kaushik, Country Director, Quantify Research