Puja Sinha

Efficient and conscientious researcher with extensive experience in conducting advanced scientific experiments, analyzing complex data sets, and publishing findings in peer-reviewed journals. Ready to apply knowledge and skills to any challenge. Highly organized and detail-oriented worker, with a drive to exceed expectations. Seeking to leverage scientific skills and knowledge to contribute to team success.

• Awarded travel grant for SFN-2019 from Department of Neuroscience, McKnight Brain Institute, University of Florida, USA.
• Qualified through All India Combined Entrance Examination for Biotechnology (CEEB), 2008 conducted by JNU, New Delhi and sponsored by Department of Biotechnology, Government of India.
• Department of Biotechnology (DBT) (Government of India) scholarship for postgraduate studies in Biotechnology (2008-2010)
• Qualified GATE (with BT) in 2010 & GATE (with XL) in 2009
• Qualified UGC - CSIR NET exam for LS in June 2010
• Obtained distinction in chemistry and first class honours in graduation, 2008.

• Kim JW, Manickam R, Sinha P, Xuan W, Huang J, Awad K, Brotto M, Tipparaju SM. P7C3 ameliorates barium chloride-induced skeletal muscle injury activating transcriptomic and epigenetic modulation of myogenic regulatory factors. J Cell Physiol. 2024 Jun 30. doi: 10.1002/jcp.31346. Epub ahead of print. PMID: 38946152.
• Sinha P, Rani A, Kumar A, Riva A, Brant JO, Foster TC. Examination of CA1 Hippocampal DNA Methylation as a Mechanism for Closing of Estrogen's Critical Window. Front Aging Neurosci. 2021;13:717032. Published 2021 Aug 4. doi:10.3389/fnagi.2021.717032
• L. J. Strath, L. Meng, A. Rani, P. Sinha, A. J. Johnson, Z. Huo, T. C. Foster, J. D. Edburg, R. B. Fillingim & Yenisel Cruz-Almeida. Accelerated Epigenetic Aging Mediates the Association between Vitamin D Levels and Knee Pain in Community-Dwelling Individuals. J Nutr Health Aging (2022). https://doi.org/10.1007/s12603-022-1758-z
• Cruz-Almeida Y, Johnson A, Meng L, Sinha P, Rani A, Yoder S, Huo Z, Foster TC, Fillingim RB. 2022. Epigenetic age predictors in community-dwelling adults with high impact knee pain.Molecular Pain. 18:1-13; 17448069221118004. PMID 35968561 DOI:10.1177/174480692211180
• Manickam R, Tur J, Badole SL, Chapalamadugu KC, Sinha P, Wang Z, Russ DW, Brotto M, Tipparaju SM. Nampt activator P7C3 ameliorates diabetes and improves skeletal muscle function modulating cell metabolism and lipid mediators. J Cachexia Sarcopenia Muscle. 2022 Jan 21. doi:10.1002/jcsm.12887. Epub ahead of print. PMID: 35060352.
• Peterson JA, Meng L, Rani A, Sinha P, Johnson AJ, Huo Z, Foster TC, Fillingim RB, CruzAlmeida Y. Epigenetic aging, knee pain and physical performance in community-dwelling middle-to-older age adults. Exp Gerontol. 2022 May 28:111861. doi:10.1016/j.exger.2022.111861. Epub ahead of print. PMID: 35640781.
• Sinha P, Montesino-Goicolea S, Huo Z, Rani A, Foster TC, Cruz-Almeida Y. Enrichment of genomic pathways based on differential DNA methylation profiles associated with chronic musculoskeletal pain in older adults: An exploratory study. Mol Pain. 2020 JanDec;16:1744806920966902. doi: 10.1177/1744806920966902.
• Cruz-Almeida Y, Sinha P, Rani A, Huo Z, Fillingim RB, Foster T. Epigenetic aging is associated with clinical and experimental pain in community-dwelling older adults. Mol Pain. 2019 JanDec;15:1744806919871819. doi: 10.1177/1744806919871819. PMID: 31394966
• Puja Sinha, Seema Nara and Manisha Sachan. 2014. Epigenetic regulation of cancer: A promising approach for cancer diagnosis. International Journal of Cancer Research and Prevention 7 (1), 57.
• Puja Sinha, Kiran Singh and Manisha Sachan. 2017. Heterogeneous pattern of DNA methylation in developmentally important genes correlates with its chromatin conformation. BMC Mol Biol.;18(1): 1. PMID: 28081716
• Puja Sinha, Kiran Singh and Manisha Sachan. 2017. High resolution methylation analysis of the HoxA5 regulatory region in different somatic tissues of laboratory mouse during development Gene Expression Pattern; 23-24:59-69. PMID: 28363633
• Pamnani M, Sinha P, Nara S, Sachan M. 2014. Study of promoter DNA methylation of Sox11 and its correlation with tissue-specific expression in the laboratory mouse. Gene 552: 133-139. PMID: 25234735
• Pamnani M, Sinha P, Singh A, Nara S, Sachan M. 2016. Study of Sox9 and Oct4 promoter methylation and its correlation with expression during testis development in laboratory mouse. Genetics and Molecular Biology. PMID: 2738163
• Pamnani M, Sinha P, Sachan M. 2013. Epigenetic modifications as prognostic markers in cancer. Research Journal of Biotechnology vol. 6(8): 66-75.
• Puja Sinha, Meenal Rastogi, Vishnu Agarwal and Manisha Sachan. 2016. Protein, Methylated DNA and Micro RNA: Potential Candidates towards Sustainable Ovarian Cancer Diagnostics.Recent Advances in Ovarian Cancer (Book chapter).

• Puja Sinha and Thomas C Foster “Effect of age and estrogen on whole genome DNA methylome profiling of CpGs in CA1 region of the hippocampus” poster presented at the 49th Annual meeting of the Society for Neuroscience at McCormick Place in Chicago, IL, October 19-23, 2019.
• Puja Sinha, Manisha Sachan, “Heterogeneous DNA methylation on promoters/coding region and chromatin assembly” poster presented at international conference on Health, Environment & Industrial Biotechnology (BioSangam-2013), held at MNNIT Allahabad, November 21-23, 2013.
• Puja Sinha, Manisha Sachan, “The extent of CpG methylation and its role in regulating chromatin conformation in promoter/ regulatory regions of genes playing important role during mammalian development” poster presented at international conference on “Gene networks in
  chromatin/chromosome function” JNCASR Jakkur, Banglore, 2015.
• Completed workshop on “Genomics Program RNASeq Laboratory Training” organized byUniversity of South Florida, Genomics Core, February 2022.
• Participated in workshop on “Bioinformatics 101 for Cancer Researchers” organized by University of Florida Health Cancer Center and Interdisciplinary for Biotechnology Research, March 2019.
• Participated in workshop on “Flow Applications In Basics, Applied And Clinical Biology (FABACTCS 2016)” organized by BSBE, IITG & BBCI at Guwahati, Nov. 03-05, 2016.
• Participated in workshop on “Scientific Paper Writing” organized by The National Academy of Sciences (NASI) at Lucknow, Jan. 06-08, 2012.
• Attended conference on “4th Meeting of the Asian Forum of Chromosome and Chromatin Biology 2012” held at CCMB, Hyderabad.

Manoj Dokania  

Senior Research Scientist at Biocon BMS R & D Centre,

Bengaluru

manojdtycoon@gmail.com                                                                   

Nationality: Indian                                                                                                       Language known: Hindi, English 

DOB: November 1986 

D/o Late Mithilesh Prasad and Smt. Anjana Sinha

Permanent & Correspondence address: C/O Awadhesh Kumar, Bhikhana Pahari, Pucca Bari, Patna, Bihar (800004)