RAVINDRA SHIRODKAR
MUMBAI
Summary
Innovative Process Research & Development Scientist with 8.8 years of experience in API process development and optimisation. Skilled in designing scalable manufacturing processes and managing technology transfers. Expertise includes impurity control, yield enhancement, process troubleshooting, and GMP documentation, ensuring efficient transition from laboratory to commercial scale.
Overview
3
3
Languages
9
9
years of professional experience
Work History
Senior Research Associate
NJ Bio India Pharmaceutical Pvt. Ltd.
MUMBAI, INDIA
01.2023 - Current
- Developed scalable synthetic routes for complex pharmaceutical intermediates, enhancing production capabilities.
- Optimized reaction conditions, resulting in improved yield and purity of pharmaceutical products.
- Supported kilogram-scale synthesis and process validation activities.
- Collaborated with analytical, QA, and manufacturing teams to facilitate seamless technology transfer.
- Performed process troubleshooting during laboratory and pilot-scale batches.
- Prepared technical reports, batch records, SOPs, and GMP documentation.
- Delivered projects for international pharmaceutical clients.
SCIENTIST-1
Hikal Ltd
PUNE, INDIA
05.2021 - 12.2023
- Reduced process variability and improved reaction yield, leading to a better impurity profile.
- Reduced process variability through reaction optimisation.
- Optimised manufacturing process for Trifloxystrobin Intermediate, enhancing product quality.
- Supported commercial production scale-up to 2–3 metric tons, facilitating consistent output.
- Assisted in transferring technology between teams to ensure successful implementation.
Research Associate
Syngene International Ltd
BANGALORE, INDIA
03.2019 - 04.2021
- Synthesized APIs, NCEs and advanced intermediates.
- Performed route scouting and synthetic optimization.
- Maintained GLP documentation and electronic laboratory notebooks to ensure laboratory compliance and data integrity.
- Contributed to CRO projects enhancing drug development for US and European pharmaceutical firms.
JR OFFICER
Vadhivarhe specility chemical ltd
Nashik, India
08.2017 - 02.2019
- Contributed to development of API molecules, including telmisartan and mesalamine.
- Developed synthesis protocols, ensuring timely completion.
- Optimised process development and alternative synthetic routes to enhance efficiency.
- Planning project activities and implementing project plans within present budgets deadlines.
- Experience of Pilot plant and Troubleshooting.
- Novel molecules to meet the quality as per desired criteria.
- Demonstrated proficiency in chemistry software such as ChemDraw and ChemSketch, along with research tools like Reaxys and SciFinder.
Education
Master of Science - Organic Chemistry
K.T.H.M college
Nashik, MH01-2017
Bachelor of Science - BSc
Arts, Science and commerce college
Rahata, MH01-2015
Skills
- Process optimization
- Route synthesis
- Scale-up processes
- Technology transfer
- GMP compliance
- Quality assurance
- Technical reporting
- Technical troubleshooting
- Continuous improvement
- Cross-functional teamwork
- Team leadership
- Literature analysis
- Research methods
Languages
English
Upper Intermediate
B2
Hindi
Advanced
C1
Marathi
Proficient
C2
Interests
- Cricket
- Travelling
Custom Section
Core Competencies
- API Process Development
- Process Research & Development
- Route Scouting
- Route Optimization
- Process Scale-up (mg to Commercial Scale)
- Technology Transfer
- Multi-step Organic Synthesis
- Impurity Identification & Control
- Reaction Optimization
- Cost Reduction & Process Improvement
- Commercial Manufacturing Support
- Troubleshooting
- GLP/GMP Documentation
- NMR, LC-MS, HPLC, GC & IR Interpretation
- Risk Assessment
- Batch Manufacturing Support
Timeline
Senior Research Associate
NJ Bio India Pharmaceutical Pvt. Ltd.
01.2023 - Current
SCIENTIST-1
Hikal Ltd
05.2021 - 12.2023
Research Associate
Syngene International Ltd
03.2019 - 04.2021
JR OFFICER
Vadhivarhe specility chemical ltd
08.2017 - 02.2019
Master of Science - Organic Chemistry
K.T.H.M college
Bachelor of Science - BSc
Arts, Science and commerce college