RAVI TEJA AYYAGARI
CHENNAI
Summary
Experienced upstream cell culture scientist with over 10+ years of experience. My core expertise is in Clone Screening, Media Screening, Early and Late stage Process Development, Scale-down Model Development, Process Characterization, Tech transfer, Scale-Up, Process Validation.
I have significant experience as a hands-on scientist early on in the career and have led a team of over 4 scientists by mentoring and coaching.
Overview
11
11
years of professional experience
1
1
Certification
Work History
Associate Scientific Manager
Biocon
Chennai
08.2021 - Current
- Project lead for early stage process development which involves clone screening and process development across different scales including Ambr15, ambr250, 5L and 50L.
- Followed Qbd and statistical approaches for design of experiments (DoE) for the process optimization at early stage development.
- Developed N-1 perfusion models for scale up.
- Used coordination and planning skills to achieve results according to schedule.
- Used critical thinking to break down problems, evaluate solutions and make decisions.
- Learned new skills and applied to daily tasks to improve efficiency and productivity.
- Completed paperwork, recognizing discrepancies and promptly addressing for resolution.
Scientist I
CuraTeQ Biologics
Hyderabad
06.2016 - 08.2021
- Process characterization study. Having good knowledge of QbD and DoE for the design of experiments. Design of experiments & screening the interactions between key parameters. Scale down model development.
- Involved in complete lab design, resource planning, procurement and qualifications of cell culture equipment.
- Training and mentoring freshers. Documented changes during experiments, noting unexpected issues arising during research activities.
- Conducted experiments in laboratory environment for product development purposes and scale up to manufacturing.
- Read literature related to scientific area of expertise to remain current in knowledge.
- Performed complex troubleshooting and led team to solve challenging scientific problems.
Research Associate
Kemwell Biopharma
Bengaluru
03.2015 - 06.2016
- Gap analysis and resource management.
- Gathered, arranged and corrected research data to create representative graphs and charts highlighting results for presentations.
- Collaborated with leadership team to identify relevant questions and determine best methods of collection.
- Streamlined research processes to meet tight deadlines for multiple projects.
- Helped team meet regulatory requirements by coordinating documentation and filings.
Junior Resaerch Associate
Hetero Biologics
Jadcherla
01.2012 - 03.2015
- Development, optimization, and scale-up of the process and feed parameters for Recombinant Monoclonal antibodies and Recombinant proteins (biosimilar) production in CHO cells.
- Optimization and process establishment in single use bioreactors and scale up.
- Collaborated with team members to achieve target results.
- Identified issues, analyzed information and provided solutions to problems.
- Created spreadsheets using Microsoft Excel for daily, weekly and monthly reporting.
Education
Master of Science - Applied Microbiology
Vellore Institute of Technology
Vellore06.2010
Bachelor of Science - Biotechnology
KGRL Degree College
Bhimavaram04.2008
Skills
- Flexible and Adaptable
- Flexible & Adaptable
- Collaboration
- Conflict Resolution
Accomplishments
- Achieved seed train intensification of cell growth through N-1 perfusion within limited timespan.
- Cell culture lab design involved in purchase, set up and qualification of lab equipment, resource planning and procurement.
Certification
Six Sigma green belt (ISI)
Timeline
Associate Scientific Manager
Biocon
08.2021 - Current
Scientist I
CuraTeQ Biologics
06.2016 - 08.2021
Research Associate
Kemwell Biopharma
03.2015 - 06.2016
Junior Resaerch Associate
Hetero Biologics
01.2012 - 03.2015
Master of Science - Applied Microbiology
Vellore Institute of Technology
Bachelor of Science - Biotechnology
KGRL Degree College
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