Roshan Gharat

• Handled distillation processes for both final products such as Dihydromyrcenol and Myrcene, as well as solvent recovery (Toluene).
• Managed multiple types of reactions including:
  Diels-Alder reaction
  Exothermic reactions
  Cyclization reactions
• Worked with a range of industrial equipment such as:
  SSR (Stainless Steel Reactor)
  GLR (Glass Lined Reactor)
  Steam Ejector
  Distillation Column
• Handled hazardous and non-hazardous chemicals, including:
  Sulphuric acid, Aluminium chloride, Sodium bicarbonate, Sodium carbonate
  Butylated Hydroxy Toluene, Triethanolamine
• Solvent handling experience includes Toluene, Methanol, Myrcene, and Dihydromyrcene.

🔹 Shift & Production Management:

• Ensured production processes were executed strictly as per Process Order Control Procedure (POCP).
  
• Oversaw manpower availability during shifts and managed overtime effectively.
  
• Coordinated timely issuance of raw materials from the store to meet batch schedules.
  
• Conducted in-process inspections, took corrective actions based on POCP results.
  
• Faced and assisted in internal and external audits with full documentation readiness.
  
• Supervised handover of final products to the store department post QC approval.
  
• Collaborated with engineering for timely preventive maintenance (PM) to avoid breakdowns.
  
• Promoted safe practices in production operations and attended safety mock drills.
  
• Participated in revising Batch Manufacturing Records (BMR) for yield improvement.
  
• Documented every batch process and conducted studies on failure batches for RCA.
  
• Maintained high standards in housekeeping and enforced discipline in the plant.
  
• Successfully achieved monthly production targets within planned timelines.
  
• DSC operating system

🔹 Process & Reaction Handling

• Independently and collaboratively managed production operations in accordance with GMP guidelines.
• Handled bromination reaction to synthesize dibromo ester.
• Conducted reduction reactions using sodium borohydride (NaBH₄) and tetrahydrofuran (THF) to produce dibromo alcohol.
• Executed oxidation reactions with manganese dioxide (MnO₂) to convert alcohols into aldehydes.
• Experienced in operating and monitoring Roto Cone Vacuum Dryer (RCVD) for efficient drying of intermediates and final products.

🔹 Compliance & Documentation

• Followed equipment cleaning procedures as per Equipment Cleaning Record (ECR) and ensured adherence to GMP standards.
• Ensured timely documentation and compliance of all process parameters, cleaning logs, and BMR entries.

🔹 Operations Management

• Arranged and ensured the availability of raw materials for scheduled batches.
• Efficiently managed shift manpower, balancing workloads and ensuring smooth shift transitions.
• Maintained seamless coordination with cross-functional teams (QA, QC, Engineering, Stores) to meet production timelines.

🔹 Safety & Quality

• Adhered to safety protocols during handling of sensitive chemicals and reactions.
• Participated in regular safety drills and ensured operational hygiene and plant discipline.
• Focused on continuous improvement through yield enhancement and reaction optimization studies

• Executed Friedel–Crafts acylation reaction using Aluminium chloride for the synthesis of Ketoprofen Nitrile, a moisture-sensitive compound carried out under nitrogen blanketing.
• Scaled up reactions from lab to plant scale, ensuring seamless technology transfer and process reproducibility.
• Handled autoclave operations with nitrogen pressure for small-scale reactions requiring high-pressure inert atmospheres.
• Carried out diazo and coupler preparation for Mesalazine synthesis, managing H₂S gas scrubbing using caustic solutions to ensure environmental and personnel safety.
• Performed hydrolysis reactions using caustic and water, followed by acidification to isolate desired products.
• Executed reduction processes using sodium sulfite and sulfur, maintaining strict control over reaction exotherms and yield.

🔹 GMP & Regulatory Compliance

• All processes executed in GMP-compliant facility certified by USFDA, ensuring adherence to quality, safety, and documentation protocols.
• Led and maintained comprehensive documentation including Batch Manufacturing Records (BMR), Equipment Cleaning Records (ECR), and process logs, ensuring full readiness for regulatory audits.
• Ensured process validation and cleaning validation requirements were met for every product campaign.

🔹 Equipment Handled

• SSR, GLR, Distillation Columns, RCVD, Autoclave, Steam Ejectors
• Experience with vacuum systems and inert atmosphere setups

🔹 Team & Shift Management

• Managed manpower planning, shift allocations, and on-time raw material coordination to meet production schedules.
• Demonstrated ability to work individually or in team environments across plant and lab setups.

🔹 Safety & Environmental Focus

• Maintained strict compliance with plant safety SOPs including handling of toxic gases (e.g., H₂S).
• Participated in safety mock drills and implemented corrective actions to avoid incidents.
• Ensured proper waste disposal and environmental control practices were followed during each campaign.