Rupal Kolamkar
Research Associate
Valpoi
Summary
Enthusiastic individual eager to contribute to team success through hard work, attention to detail and excellent organizational skills. Motivated to learn, grow and excel in Research and Development. Well-organized with good project management and planning abilities developed over 3 years in Pharmaceutical and Agrochemical Industry. Ability to handle multiple projects simultaneously with a high degree of accuracy. Passionate about learning and adapting to day-to-day Technologies.
Overview
3
3
years of professional experience
2
2
Languages
Work History
Junior Chemist
Syngenta Biosciences
Old Goa
01.2022 - Current
- Carried out various reactions at milligram to kilo scale.
- Capable of handling multiple projects simultaneously.
- Well versed with handling atmospherically unstable reactions and reagents.
- Successfully delivered 8 projects including metabolites with requirement 98% purity, Chiral molecule with requirement of enantiomeric excess of 98% and intermediates.
- Able to handle various hazardous chemicals safely in large quantities including n-Butyl Lithium, LDA, Tri-fluoromethanesulfonic acid, Pivalic Acid, reducing reagents, Grignard reagent, triphosgene, thiols, oxiranes, peroxides.
- Carried out various reactions like substitution, salt formation, deprotection, oxidation, Dakin- west, metal-induced coupling reactions, Hydrolysis, Claisen rearrangement, Cyanation, Reductive amination, Krapcho decarboxylation. Grignard reaction.
- Well versed at handling instruments like HPLC, GC, LCMS for monitoring of reactions and combi-flash for chromatography and reverse chromatography.
- Developed interpretational knowledge of various instruments skills like NMR, GC, IR, UV, HPLC, DSC and LCMS to characterize synthesized compounds.
- Proficient at using large reactors independently up to 100 liters, centrifuge, nutsche filters, 50 L rotary evaporators.
- Carried out large scale column purification up to 100kg.
- Timely and accurate documentation using ELN and RDM.
- Super-User of Vacuum oven and AODD pumps and responsible for audit of hydrogenation lab and glassware store.
Research Chemist
Sphaera Pharma
Gurugram
08.2021 - 12.2021
- Worked in drug discovery.
- Carried out various reactions from milligram to grams scale.
- Carried out on average of 40 reactions per month.
- Performed reactions such as HATU coupling, Ullmann coupling, Negishi coupling, Hydrogenation, Hydrolysis, etc.
- Timely update of Lab Notebook with complete information on synthesized molecule.
- Well-versed with use of SciFinder, Reaxys, etc for literature survey required for synthesis of desired compounds.
- Expert in handling of air-sensitive, moisture-sensitive reactions.
- Handled instruments such as parr shaker, HPLC, Rota vapour etc.
Research Associate
Unichem Laboratories Limited
Pilerne
01.2020 - 08.2021
- Carried out various reactions at different size scales from grams to kilogram scale.
- Carried various moisture-sensitive and air-sensitive reactions Sound knowledge and expertise in various oxidation and reduction reactions.
- Handled various hazardous reagents with proper knowledge of MSDS and proper PPE.
- Familiar with various purification and isolation techniques such as column chromatography, and crystallization.
- Performed various reactions like acid-amine coupling, Heck reaction, Buchwald Coupling, Protection and deprotection of functional groups, Nucleophilic substitution reaction, NaBH4 reduction, etc.
- Has sound knowledge of technique as NMR, and IR for characterization of various organic compounds.
- Collaborated with Tech-Transfer team to carry out large scale production at Pithampur Plant
- Used various science information tools like Reaxys, and SciFinder for literature and patents knowledge
Education
Master of Science - Organic Chemistry
Goa University
Taleigao, Goa 06.2017 - 05.2019
Bachelor of Science - Chemistry
St. Xavier's Chemistry
Mapusa, Goa 06.2014 - 05.2017
Skills
ELN and RDM for data documentation
HPLC, GC, LCMS, GCMS handling and interpretation
NMR, QNMR, FNMR interpretation
MS office
Verbal and written communication skills
Basic chemistry
Timeline
Junior Chemist
Syngenta Biosciences
01.2022 - Current
Research Chemist
Sphaera Pharma
08.2021 - 12.2021
Research Associate
Unichem Laboratories Limited
01.2020 - 08.2021
Master of Science - Organic Chemistry
Goa University
06.2017 - 05.2019
Bachelor of Science - Chemistry
St. Xavier's Chemistry
06.2014 - 05.2017
Refernces
Dr. Sunil Kumar A
Research Executive
Unichem Laboratories
Pilerne- 403515, Goa
Email :skadiyodi@gmail.com
Mr. Prafulla B. Nagawade
Senior Research Executive
Unichem Laboratories
Pilerne- 403515, Goa
Email : prafulla.pb@gmail.com
Personal Information
- Name : Rupal Mohan Kolamkar
- Gender : Male
- Date of Birth : 10/11/1996
- Marital Status : Unmarried
- Nationality : Indian
- Languages Known : English, Konkani, Marathi and Hindi
Refernces
Dr. Sunil Kumar A
Research Executive
Unichem Laboratories
Pilerne- 403515, Goa
Email :skadiyodi@gmail.com
Mr. Prafulla B. Nagawade
Senior Research Executive
Unichem Laboratories
Pilerne- 403515, Goa
Email : prafulla.pb@gmail.com