Sangeetha Mohan

Seeking a full-time research and development position in synthetic, medicinal, or natural products chemistry, or a related field. Passionate about contributing to innovative scientific advancements through meticulous research and high-quality work. Eager to take on a challenging role where my expertise can contribute to meaningful progress while making a positive impact on the environment and society.

• Linker-Based Pharmacophoric Design and Semisynthesis of Labdane Conjugates Active against Multi-Faceted Inflammatory Targets, Sangeetha Mohan, Krishnan, L., Madhusoodanan, N., Sobha, A., Jalaja, R., Kumaran, A., Vankadari, N., Purushothaman, J., Somappa, S. B., ACS J. Agric. Food Chem., 2024, 72, 12, 6389–6401
• Ligand-Based Pharmacophoric Design and Anti-Inflammatory Evaluation of Triazole Linked Semisynthetic Labdane Conjugates, Sangeetha Mohan, Krishnan, L., Madhusoodanan, N., Sobha, A., Babysulochana, A. D., Vankadari, N., Purushothaman, J., Somappa, S. B., ACS Med. Chem. Lett., 2024, 15, 8, 1260–1268
• Lead Optimization of Labdane Conjugates into Novel Therapeutics for Inflammation Modulation, Sangeetha Mohan, Krishnan, L., Vankadari, N., Purushothaman, J., Somappa, S. B., Manuscript to be communicated
• Antibacterial Natural Products from Microbial and Fungal Sources: A Decade of Advances, Sangeetha Mohan, Krishna, M. S. A., Chandramouli, M., Keri, R. S., Patil, S. A., Ningaiah, S., Somappa, S. B., Mol. Divers., 2022, 27, 1, 517–541
• Marine Based Natural Products: Exploring the Recent Developments in the Identification of Antimicrobial Agents, Krishna, A., Sangeetha Mohan, Ashitha, K. T., Chandramouli, M., Alaganandam, K., Ningaiah, S., Babu, S. K., Somappa, S. B., Chem. Biodivers., 2022, 19, Equally Contributed
• Pyrazole Appended Hetero-Hybrids: Bioisosteric Design, Synthesis, In silico and In Vitro Antibacterial and Anti-inflammatory Evaluations, Sobha, A., Sangeetha Mohan, Madhusoodanan, N., Krishnana, G. V., Varughese, S., Kumar, B. S. D., Ningaiah, S., Shridevi, D., Somappa, S. B., J. Mol. Struct., 2023, 1289, 135780
• Eco-Friendly Anticorrosive Epoxy Coating from Ixora Leaf Extract: A Promising Solution for Steel Protection in Marine Environment, Veedu, K. K., Sangeetha Mohan, Somappa, S. B., Gopalan, N. K., J. Clean. Prod., 2022, 340, 130750
• Anti-Hyperlipidemic Potential of Natural Product Based Labdane-Pyrroles via Inhibition of Cholesterol and Triglycerides Synthesis, Jalaja, R., Leela, S. G., Sangeetha Mohan, Nair, M. S., Gopalan, R. K., Somappa, S. B., Bioorg. Chem., 2021, 108, 104664
• Novel Small Molecule-Based Acetylcholinesterase (AChE) Inhibitors: From Biological Perspective to Recent Developments, Sobha, A., Ganapathy, A., Sangeetha Mohan, Madhusoodanan, N., Babysulochana, A. D., Alaganandan, K., Somappa, S. B., Eur. J. Med. Chem. Reports, 2024, 12, 100237
• Exploring Novel Triazole Derivatives as Multi-Target-Directed-Ligands: A Promising Avenue to Attenuate Alzheimer’s Disease, Sobha, A., Krishnan, L., Doddamani S. V., Vijayakumar S., Sangeetha Mohan, Pai S. A., Ghosh D., Purushothaman, J., Somappa, S. B., Manuscript to be communicated
• Discovery of Phthalimide Benzylpyridinium Derivatives as Multifunctional Agents against Alzheimer’s Disease, Sobha, A., Krishnan, L., Sangeetha Mohan, Purushothaman, J., Somappa, S. B., Manuscript under preparation

• Natural Product-based Pharmacophoric Design and Semi-Synthesis of Labdane Conjugates Active against Multi-Faceted Inflammatory Targets, Sangeetha Mohan, Lekshmy Krishnan, Naveen Vankadari, Jayamurthy Purushothaman, Sasidhar B. Somappa, 36th Kerala Science Congress, Government College, Kasaragod, Kerala, 02/09/24, Oral presentation
• Mitochondriotropic Oleanolic Acid TPP Conjugates: Isolation, Semi-Synthesis and Antioxidant Evaluation, Sangeetha Mohan, Michael G. Ibok, Raghu K. Gopalan, Sasidhar B. Somappa, National Seminar on Recent Trends in Disease Prevention and Health Management, CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, Kerala, 12/14/22, Poster presentation
• Triphenylphosphine conjugates of oleanolic acid isolated from macrostyla longistyla as potential mitochondrial antioxidants, Sangeetha Mohan, Michael G. Ibok, Raghu K. Gopalan, Sasidhar B. Somappa, International Seminar on Plant Chemistry, Gene Prospecting and Clinical Biology, Kerala Academy of Sciences, Thiruvananthapuram, Kerala, 11/10/22, Oral presentation

• CSIR-National Institute for Interdisciplinary Science and Technology, Thiruvananthapuram, Kerala, 695019, India
• St. Agnes College, Mangaluru, Karnataka, India
• Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia

• English
• Malayalam
• Hindi

• Dr. Sasidhar B. S., Principal Scientist, Chemical Sciences and Technology Division (CSTD), CSIR-National Institute for Interdisciplinary Science & Technology, Thiruvananthapuram, Kerala, 695019, India, 9497260897, drsasidharbs@niist.res.in
• Dr. Jayamurthy P., Agro Processing and Technology Division, CSIR-National Institute for Interdisciplinary Science & Technology, Ministry of Science and Technology, Govt. of India, Thiruvananthapuram, Kerala, 695019, India, 9746459990, pjayamurthy@niist.res.in
• Dr. Naveen Vankadari, Research Fellow, Bio21 Institute, University of Melbourne, Melbourne, Victoria, Australia, 0416074778, naveen.vankadari@unimelb.edu.au

• Qualified CSIR-UGC National Eligibility Test (NET), 2017
• Awarded Junior Research Fellowship, University Grants Commission, New Delhi, India
• Awarded Senior Research Fellowship, University Grants Commission, New Delhi, India
• Recipient of Prof. Dr. A. Hisham Endowment Award in Phytochemistry, 2024, Kerala Academy of Sciences

• Designing and executing multi-step synthesis, purification and characterization of natural products and heterocycles
• Extraction, isolation and characterization of molecules from natural sources
• Experienced in structure elucidation of organic compounds using spectral data like IR, NMR and HRMS
• Familiar with various techniques for separation of compounds and instruments like IR spectrometer, HPLC and UV
• Semi-synthetic modifications of natural products into biologically relevant scaffolds
• Computer awareness: Chemdraw, Mendeley, Endnote, MestRenova, Topspin, Scifinder, MS office etc.