Summary
Overview
Work History
Education
Skills
Accomplishments
Personal Information
Publications
Projects
Other achievements
Hobbies
Timeline
Generic

Siddharth Jadeja

Hradec Kralove

Summary

A Ph.D. researcher specializing in developing LC-MS-based methods for analyzing biopharmaceuticals and proteins. I possess three years of industrial research experience developing chromatographic methods for analyzing pharmaceutical compounds. I aspire to utilize my scientific and professional skills to contribute meaningfully to the healthcare sector.

Overview

6
6
years of professional experience

Work History

Research Trainee

Technical University Of Munich
04.2022 - 09.2022

Research Internship under the guidance of Prof. Dr. Bernhard Kuster, Chair of Proteomics and Bioanalytics. Gained practical experience in nano liquid chromatography, mastering instrument operation, method optimization, and its application in proteomics research.

Senior Research Associate

Syngene International
05.2017 - 12.2019
  • Developed and validated liquid chromatographic methods to quantify pharmaceutical compounds.


Research Intern

Syngene International
06.2016 - 03.2017
  • Developed a rapid and simple analytical method for quantifying cations in peritoneal dialysis solution using ion exchange chromatography technique and suppressed conductivity detection.

Education

Ph.D. - Analytical Chemistry

Charles University, Faculty of Pharmacy
Hradec Kralove, Czechia
08.2024

Master of Pharmacy - Pharmaceutical Analysis and Quality Assurance

Manipal College of Pharmaceutical Sciences
Manipal, India
07.2017

Bachelor of Pharmacy -

Ramanbhai Patel College of Pharmacy
Changa, India
05.2015

Skills

  • Analytical method development
  • Mass spectrometry
  • Liquid Chromatography
  • Proteomic analysis
  • Peptide mapping

Accomplishments

  • Analytical Method Development
  • Analytical Method Validation
  • Good Laboratory Practices
  • Good Documentation Practices
  • Good Presentation and Communication Skills

Personal Information

  • Place of Birth: India
  • Date of Birth: 08/04/1994

Publications


2023: Jadeja S et al. A stationary phase with a positively charged surface allows for minimizing formic acid concentration in the mobile phase, enhancing electrospray ionization in LC-MS proteomic experiments. The Analyst, DOI:10.1039/D3AN01508D

2023: Naplekov D et al. Robust, and Repeatable Online Acid Cleavage of Proteins in Mobile Phase for Fast Quantitative  LC-MS Bottom-Up Protein Analysis─Application for Ricin Detection. Analytical Chemistry, DOI:10.1021/acs.analchem.3c01772

2022: Lenco J et al. Reversed-Phase Liquid Chromatography of Peptides for Bottom-Up Proteomics: A Tutorial. Journal of  Proteome Research, DOI: 10.1021/acs.jproteome.2c00407

2021: Khalikova M el al.Evaluation of strategies for overcoming trifluoroacetic acid ionization suppression resulted in single-column intact level, middle-up, and bottom-up reversed-phase LC-MS analyses of antibody biopharmaceuticals. Talanta, DOI:  10.1016/j.talanta.2021.122512


Projects

  • Principal investigator, Grant Agency Charles University, GA-UK No. 370522, Potential of weak acidifiers of mobile phase to boost the sensitivity of proteomic bottom-up LC-MS analyses
  • Research-coworker, Grant Agency Czech Republic, GAČR No. 22-21620S, Minimization and potential utilization of negative effects of high mobile the temperature of column and phase in proteomic analyses

Other achievements

  • 2022: Best Student Poster Award at the 16th Central and Eastern European Proteomic Conference in Prague
  • 2017: An award for being "The Best Outgoing Student of M.Pharm-Pharmaceutical Analysis Quality Assurance Specialization for the Academic Year 2016-17"

Hobbies

Public speaking is a hobby and a tool to enhance my confidence and share my research findings with the world. I have participated in more than ten domestic and international conferences, sharing my research findings and learning new advancements in my field.

Timeline

Research Trainee

Technical University Of Munich
04.2022 - 09.2022

Senior Research Associate

Syngene International
05.2017 - 12.2019

Research Intern

Syngene International
06.2016 - 03.2017

Ph.D. - Analytical Chemistry

Charles University, Faculty of Pharmacy

Master of Pharmacy - Pharmaceutical Analysis and Quality Assurance

Manipal College of Pharmaceutical Sciences

Bachelor of Pharmacy -

Ramanbhai Patel College of Pharmacy
Siddharth Jadeja