Sourabh Shenoy
Karkala
Summary
Knowledgeable about research areas and study procedures. Enthusiastic about setting up and carrying out a wide array of studies. Diligent, industrious and efficient in handling minute details with methodical approaches to gain insights into the Aging and molecular biology field.
Overview
3
3
Languages
4
4
years of professional experience
Work History
Research trainee
Oklahoma Medical Research Foundation (OMRF)
07.2025 - 06.2026
- Role of Esco2 in Chromosome Dynamics during Early Xenopus laevis Embryogenesis
- Advisor: Susannah Rankin, PhD, Cell Cycle and Cancer Biology Department, Oklahoma Medical Research Foundation (OMRF), Oklahoma City, USA
- Investigated the regulatory role of Esco2 (Establishment of sister chromatid cohesion N-acetyltransferase 2) in cohesin complex dynamics and sister chromatid cohesion during early embryonic cell division.
- Established Xenopus laevis embryonic model systems via surgical dissection for male testes harvesting and performing in vitro fertilization.
- Executed targeted protein degradation at Stage 1 using microinjection of the Trim-Away system alongside molecular fluorescent markers.
- Performed live and fixed-cell high-resolution imaging at late Stage 9 and Stage 10 using a Nikon Eclipse Ti2 confocal microscope system.
- Quantified chromosomal dynamics and spatial organization across developmental stages using Nikon analysis software.
- Collected and documented experimental data with accuracy for supervisor review
- Operated standard laboratory equipment following established protocols and safety guidelines
- Followed biosafety and quality control procedures during routine lab tasks
- Supported project teams by completing assigned research tasks and adapting to changing priorities
- Improved experimental accuracy by diligently troubleshooting issues with equipment or methodology during all phases of the research process.
- Prepared laboratory reagents and maintained sterile workspaces for daily research activities
- Participated in regular lab meetings to discuss ongoing projects, share ideas, and receive constructive feedback from team members.
- Adapted quickly to new technologies or techniques introduced into the lab setting, maximizing productivity and minimizing downtime due to learning curves.
- Developed strong working relationships with fellow researchers and staff, fostering a positive and collaborative work environment.
- Maintained detailed records of experimental procedures and results using electronic lab notebooks for easy reference by other researchers.
- Attended meetings and presentations to learn project details.
- Completed research, compiled data, updated spreadsheets, and produced timely reports.
Intern
SDM Centre for Research in Ayurveda & Allied Sciences
02.2024 - 02.2024
- Antioxidant & Cytotoxic Activity of Ziziphus jujube Hydroalcoholic Extract
- Evaluated the anti-cancer and antioxidant properties of Ziziphus jujube leaf extract across targeted cellular models.
- Prepared plant extracts and executed phytochemical screening to profile flavonoid concentration and composition.
- Maintained cell line cultures to perform in vitro cytotoxicity assays and evaluate cell viability.
- Ziziphus jujube extract has cytotoxicity effect when used in 1000mg/ml concentration.
- Maintained accurate records for experiments, observations, and reference materials.
- Prepared presentations, summaries, and working notes for internal research discussions.
- Udupi, India
- One month
Research Intern – Microbiology & Biochemistry
Euchem Labs
10.2022 - 10.2022
- Executed microbiological isolation of bacterial strains from water samples using selective inoculation techniques.
- Performed analytical biochemical testing on soil and water samples, including chlorine quantification and buffer preparation.
- Brahmavar, India
- Supported laboratory research by preparing samples, reagents, and documentation for ongoing experiments.
Education
Masters by Research - Life Sciences
Manipal School of Life Sciences, MAHE
Manipal, India01-2026
BSc - Biotechnology
Sri Bhuvanendra College
Karkala, India01-2025
Skills
- Advanced microinjection techniques
- Protein degradation techniques
- Chromatin preparation and imaging
- Live cell imaging
- Advanced confocal imaging
- In vitro RNA production
- Animal cell culture techniques
- Plant extract preparation
- Selective inoculation methods
- Sample collection
- Experiment design
- Analytical techniques
- Proficient in Nikon image analysis tools
- Data interpretation
- Scientific writing
- Technical report writing
- Plasmid purification
- Data interpretation
Accomplishments
- Hands-On Workshop: "Skill Development into Wet Lab Applications: Basics of Handling Cryogenic Fluid, Rotary Flash Evaporator & Vacuum Concentrator" Manipal Government of Karnataka Bioincubator-BioNEST (November 9, 2024).
- International Conference: "Plant Biotechnology for Sustainable Productivity and Environment (ICPBSPE)" Organized by the Department of Plant Sciences, Manipal School of Life Sciences, MAHE (December 9–10, 2024).
- Pre-Conference Workshop: "Exploring the Hidden World of Microbial Diversity: Metagenomics Uncovered" Organized by the Dept. of Ophthalmology & Dept. of Microbiology, Kasturba Medical College (KMC), Manipal, in collaboration with MSLS and the Centre for Ocular Nanomedicine, MAHE (January 13–14, 2025).
- Cultural Activities: Participated in the folk-dance event during Cultural Day at MAHE.
Co-Curricular Activities & Workshops
- Hands-On Workshop: "Skill Development into Wet Lab Applications: Basics of Handling Cryogenic Fluid, Rotary Flash Evaporator & Vacuum Concentrator" Manipal Government of Karnataka Bioincubator-BioNEST (November 9, 2024).
- International Conference: "Plant Biotechnology for Sustainable Productivity and Environment (ICPBSPE)" Organized by the Department of Plant Sciences, Manipal School of Life Sciences, MAHE (December 9–10, 2024).
- Pre-Conference Workshop: "Exploring the Hidden World of Microbial Diversity: Metagenomics Uncovered" Organized by the Dept. of Ophthalmology & Dept. of Microbiology, Kasturba Medical College (KMC), Manipal, in collaboration with MSLS and the Centre for Ocular Nanomedicine, MAHE (January 13–14, 2025).
- Cultural Activities: Participated in the folk-dance event during Cultural Day at MAHE.
Languages
English
Advanced (C1)
Hindi
Intermediate (B1)
Kannada
Bilingual or Proficient (C2)
Timeline
Research trainee
Oklahoma Medical Research Foundation (OMRF)
07.2025 - 06.2026
Intern
SDM Centre for Research in Ayurveda & Allied Sciences
02.2024 - 02.2024
Research Intern – Microbiology & Biochemistry
Euchem Labs
10.2022 - 10.2022
BSc - Biotechnology
Sri Bhuvanendra College
Masters by Research - Life Sciences
Manipal School of Life Sciences, MAHE