SREESHA R SUDHAKAR
Trivandrum
Summary
Clinical Scientist with over 3.5 years of expertise in variant analysis, interpretation, and classification of oncological variants in accordance with AMP and ASCO guidelines. Proven track record of delivering comprehensive and accurate clinical reports with 100% adherence to turnaround times, significantly enhancing prognosis and patient outcomes. Currently contributing to advanced molecular profiling at 4baseCare, a leader in Precision Oncology, through meticulous genomic data analysis. Recognized for a strong foundation in clinical research, innovative problem-solving skills, and the ability to foster collaboration across multidisciplinary teams while adapting to the evolving landscape of scientific and clinical demands.
Overview
4
4
years of professional experience
1
1
Certification
Work History
Clinical Scientist
4baseCare
03.2024 - Current
- I have gained deep knowledge on understanding various solid tumours and associated Biomarker and FDA approved Drug for Variants. I currently approve reports before final dispatch, ensuring that report is perfect in every aspect. Further my role demands discussion of the case studies with clinicians
Senior Genome Analyst
MedGenome
01.2022 - 01.2024
- During my tenure here, I have prepared NGS based comprehensive reports in a specified Turnaround Time (TAT) ensuring company's operational needs in a timely basis for effective patient care. Identification, classification, and reporting of true single nucleotide variants (SNVs), Insertions and deletions (INDELs), Copy number variants (CNVs), and Fusions, all of which are crucial in understanding the molecular basis of these diseases. Additionally, I have also done fragment analysis, IGHV analysis.
Education
Ph.D. - Biology
IISER TVM
Trivandrum, India07-2020
Master of Science - Animal Biotechnology
BHARATHIAR UNIVERSITY
Coimbatore, India04-2012
Bachelor of Science - Biotechnology
Bharathiar University
Coimbatore01-2010
Skills
- Next Generation Sequencing data analysis
- Understanding true variants with the use of Integrated Genome Viewer
- Classification of somatic and germ line variants using ACMG/AMP guidelines
- Sanger data and fragment analysis
- Data mining, Literature search, well versed with FDA approvals
- Use of oncology Databases like OncoKB, Uniprot, Civic, COSMIC, Varsome, Jackson
- Attention to details, good problem-solving skills
- Good understanding of clinical/medical data
- Designing, developing and carrying out research projects
- Proficient in MS word, Excel, Powerpoint
Accomplishments
1. Awarded INnovation in Science Pursuit for Inspired REsearch [INSPIRE] Fellowship, DST • Jun 2013
2. GATE Awardee, AIR- 423, 2013
First Rank in MSc. Animal Biotechnology, Bharathiar University, Coimbatore • Jun 2013
Certification
- Metabolism in time and space, EMBO-EMBL Symposia at Heidelberg, Germany • May 2017.
- Indian Drosophila Research Conference (InDRC) Fly meet, IISER-Bhopal • Jun 2017
- Indian Society of Developmental Biology (InSDB) meeting, CCMB-Hyderabad • Jul 2015.
- All India Cell Biology Conference (AICBC), IISER & RGCB • Dec 2015
- Indian Drosophila Research Conference (InDRC) Fly meet, IIT-Kanpur • Dec 2015.
Timeline
Clinical Scientist
4baseCare
03.2024 - Current
Senior Genome Analyst
MedGenome
01.2022 - 01.2024
Ph.D. - Biology
IISER TVM
Master of Science - Animal Biotechnology
BHARATHIAR UNIVERSITY
Bachelor of Science - Biotechnology
Bharathiar University
PUBLICATIONS
- Insulin signalling elicits hunger-induced feeding in Drosophila Developmental biology, Nov 2019
- Chronic Unpredictable Stress (CUS) induced anxiety and mood disorders in a Zebrafish model: Altered brain proteome profile implicates mitochondrial dysfunction. Plos One, May 2013
References
- Jishy, Varghese, Associate Professor, jishy@iisertvm.ac.in, +91 (0)471 - 2778169
- Dr. Thernal S, Geetha, Principal scientist at Medgenome, Thernal@medgenome.com, 8737 78242
AWARDS AND SCHOLARSHIPS
- Awarded INnovation in Science Pursuit for Inspired REsearch (INSPIRE) Fellowship, DST
- Jun 2013, GATE Awardee, AIR- 423, 2013, First Rank in MSc. Animal Biotechnology, Bharathiar University, Coimbatore
- Jun 2013