Thirumoorthy Chinnasamy

Early-career researcher specializing in perinatal depression and gestational diabetes mellitus (GDM). Investigates neurobiological and epigenetic mechanisms linking maternal mental health to fetal development. Focuses on predictive biomarkers through integrative multi-omics approaches. Expertise in DNA Methylation, telomere biology, mitochondrial function, and neuroendocrine signaling. Dedicated to advancing early diagnostic tools and preventive strategies for maternal-child health using high-throughput platforms like Illumina EPIC arrays, NGS sequencing.

• 47th NEURO 2024, Fukuoka, Japan, Epigenome-wide association study of pregnant women identifies a specific panel of DNA methylation signatures for perinatal depression and postpartum depression prediction (Poster Presentation).
• 60th EASD 2024, Madrid, Spain, Epigenome-wide association study identifies a specific panel of DNA methylation signatures associated with gestational diabetes mellitus (Oral Presentation).
• IABSCON-2023, Bangalore, Altered levels of neurological biomarkers at the interface of depression and gestational diabetes mellitus with predictable delivery outcomes (Poster Presentation).
• Pre-conference Meet, NIMHANS 2024, Interplay of Telomere Length and Mitochondrial Genomic Changes in Antenatal Depression and Gestational Diabetes Mellitus: A Longitudinal Analysis (Poster Presentation).

• International Travel Grant: Awarded by the European Association for the Study of Diabetes (EASD) and the SERB–Anusandhan National Research Foundation (ANRF) to attend the 60th EASD Conference in Madrid, Spain., 09/09/24 - 09/13/24
• Academic Excellence: 3rd Rank in M.Sc. Biochemistry

• Thirumoorthy, C., Sharma, K. K., Deepa, M., Yogaprabhu, S., Sneha, J., Rekha, R. P., Venkatesan, U., Hemavathy, S., Nikhil, J., Srikumar, B. N., Binukumar, B., Radha, V., Sharma, S., Grallert, H., Ball, G., Ram, U., Anjana, R. M., Balasubramanyam, M., Tandon, N., Mohan, V., & Gokulakrishnan, K., 2025, Epigenome-wide association study identifies a specific panel of DNA methylation signatures for antenatal and postpartum depressive symptoms., Journal of Affective Disorders, 383, 15, 195–206, https://doi.org/10.1016/j.jad.2025.04.083
• Thirumoorthy, C., Rekha, R. P., Deepa, M., Ram, U., Shalu, D., Venkatesan, U., Srikumar, B. N., Anjana, R. M., Balasubramanyam, M., Mohan, V., Saravanan, P., Govindaraj, P., & Gokulakrishnan, K., 2025, Association of early pregnancy telomere length and mitochondrial copy number with gestational diabetes mellitus and depressive symptoms., Psychoneuroendocrinology, 176, 107431, https://doi.org/10.1016/j.psyneuen.2025.107431
• Thirumoorthy, C., Deepa, M., Srikumar, B. N., Hannah, W., Venkatesan, U., Nikhil, P. J., Hemavathy, S., Binukumar, B., Anjana, R. M., Ram, U., Balasubramanyam, M., Saravanan, P., Mohan, V., & Gokulakrishnan, K., 2022, Altered levels of neurobiological biomarkers at the interface of depression and gestational diabetes mellitus in Asian Indian women., Neuropeptides, 93, 102245, https://doi.org/10.1016/j.npep.2022.102245
• Gokulakrishnan, K., Nikhil, J., Viswanath B., Thirumoorthy, C., Narasimhan, S., Devarajan, B., Joseph, E., David, A. K. D., Sharma, S., Vasudevan, K., Sreeraj, V. S., Holla, B., Shivakumar, V., Debnath, M., Venkatasubramanian, G., & Varambally, S., 2023, Comparison of gut microbiome profile in patients with schizophrenia and healthy controls: A plausible non-invasive biomarker?, Journal of Psychiatric Research, 162, 140–149, https://doi.org/10.1016/j.jpsychires.2023.05.021
• Gokulakrishnan, K., Nikhil, J., Sreeraj, V. S., Thirumoorthy, C., Narasimhan, S., Nichenametla, S., Pathak, H., Shivakumar, V., Debnath, M., Venkatasubramanian, G., & Varambally, S., 2022, Altered intestinal permeability biomarkers in schizophrenia: A possible link with subclinical inflammation., Annals of Neurosciences, 29, 1, 1–7, https://doi.org/10.1177/09727531221108849
• Rani, N., Chinnasamy, T., Halasumane Swamy, V., Ramya, M., Poornachandra Rao, P., & Muddappa, S., 2021, Evidence of new calcium-dependent cysteine protease of Melia dubia latex with fibrinolytic potential., Journal of Proteins and Proteomics, 12, 2, 115–123, https://doi.org/10.1007/s42485-021-00064-z

• Gokulakrishnan K, Narasimhan S, Thirumoorthy C, et al., Role of adipokines in neuroinflammation., Inflammation – Vol 2
• Gokulakrishnan K, Thirumoorthy C, et al., Gut-Brain Axis in neuropsychiatric and neurodegenerative disorders., Inflammation – Vol 3

• Big Data Management of Epigenetic Biomarkers for Early Prediction of Perinatal Depression and Gestational Diabetes Mellitus, Warwick Medical School, University of Warwick, UK, (June-2024)
• International Symposium and Workshop on Multi-omics Databases and Discovery Tools, Jointly organized by Swami Rama Himalayan (SRH) University, India & Anglia Ruskin University, UK, (March 28,2023 - March 31, 2023) at SRH University, Dehradun, India.