Summary
Overview
Work History
Education
Skills
Accomplishments
Hobbies and Interests
Languages
Personal Information
Languages
Timeline
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Upasna Gusain

Pune

Summary

Experienced scientist in research and development within downstream processing. Proven ability to leverage technical skills to drive innovative solutions and improve operational efficiency. Committed to contributing to organizational success through effective problem-solving and collaboration.

Overview

7
7
years of professional experience

Work History

Senior Associate Scientist

Syngene International Ltd.
01.2022 - 12.2022
  • Spearheaded process development plan and supervised execution of experiments.
  • Coordinated cross-functional teams for efficient sample distribution and project meeting attendance.
  • Presented data effectively in meetings, ensuring clarity and comprehension.
  • Prepared essential documents, including protocols and process development reports.
  • Recorded data meticulously in lab notebooks to maintain accurate records.
  • Communicated with vendors to ensure timely equipment qualification and compliance.
  • Maintained lab compliance standards while training subordinates on procedures.

Associate scientist

Intas Bio-pharmaceuticals
11.2015 - 12.2021
  • Planning and execution of experiments for Viral vector purification.
  • Preparation of documents like protocols, process development reports and data recording in lab notebooks.
  • Co-ordination with cross functional teams for sample distribution, attending project meetings, taking follow-ups, data presentation in meetings.
  • Process comparability studies and consistency studies. Involvement in lab management as per QMS to generate sustainable quality. Responsible for Management of Consumables inventory and procurement using SAP.
  • Equipment commissioning (URS and SOPs, OQ, PQ, PV writing) and Maintenance of Instruments, equipment's.
  • Trained students and trainees on process execution.
  • Optimization of cell lysis condition using different detergents, chemicals and nucleases.
  • Development and optimization of chromatography steps for protein and virus purification to generate robust process.
  • Filtration: Evaluation and selection of Depth filter, Capsule filter, TFF and hollow fiber for clarification, concentration and diafiltration.
  • Centrifugation: Experience in Ultracentrifugation handling for viral vector purification.
  • Planning and execution of 10L integrity batches for protein purification.
  • Experience of 50L consistent batches for three therapeutic products (Viral vectors). Comparative study with small scale batches.
  • Hands on in Plasmid and RNA Purification (Invitro transcription|| Kit Based).

Education

Masters - biotechnology

Banasthali Vidyapith
Jaipur, Rajasthan
01.2014

Bachelors - biotechnology

Hemvati Nandan Bahuguna Garhwal University
Uttarakhand
01.2012

Skills

  • Cell lysis optimization
  • Chromatography development
  • Filtration techniques
  • Depth filter evaluation
  • Capsule filtration
  • TFF processes
  • Hollow fiber technology
  • Centrifugation methods
  • Ultracentrifugation expertise
  • Integrity batch planning
  • 50L batch consistency
  • Comparative batch analysis
  • Plasmid and RNA purification
  • In vitro transcription
  • Kit-based methodologies

Accomplishments

  • 08/01/22, Online Course in 'Writing in sciences (Stanford University)
  • 08/01/21, Avengers award for excellent performance and teamwork at Intas biopharma.
  • 08/01/20, Avengers award for contribution in the RCGM submission of gene therapy product.
  • Selection in Biotech Industrial Training Programme (BITP) by Department of Biotechnology (DBT)
  • A, B and C certification in NSS for service towards society.

Hobbies and Interests

Dancing

Playing Badminton

Languages

  • English
  • Hindi

Personal Information

Date of Birth: 11/27/91

Languages

Hindi
First Language
English
Advanced (C1)
C1

Timeline

Senior Associate Scientist

Syngene International Ltd.
01.2022 - 12.2022

Associate scientist

Intas Bio-pharmaceuticals
11.2015 - 12.2021

Masters - biotechnology

Banasthali Vidyapith

Bachelors - biotechnology

Hemvati Nandan Bahuguna Garhwal University

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Upasna Gusain