VARSHA RANJAN

Highly experienced Scientist with a strong background & understanding of scientific methodologies and research techniques. Proven ability to manage laboratory operations and lead teams in conducting complex research projects. Proficient in experimental design, data analysis, problem-solving, hypothesis testing, and report writing. Demonstrated ability to contribute to impactful research projects and collaborate effectively with interdisciplinary teams. Previous work has resulted in breakthrough findings, significant advancements in field studies, and published research papers.

• IIT-JAM qualified in the year 2016
• Biotechnology Finishing School - KBITS scholarship (year 2013-14)
• GATE qualified in the year 2013 (Valid through 2015)
• Merit scholarship for under-graduation (year 2008-12)

BHAT BIOTECH INDIA (P) LTD.

1. Design and Expression of humanized antibodies against soluble Interleukin-6 receptor (sIL-6R) and soluble glycoprotein 130 (sGP130) in bacteria and animal cell lines for the treatment of Rheumatoid Arthritis Contents: Cloning, expression and purification of soluble IL-6 receptor, IL-6, soluble gp130 in animal cell lines and bacteria, development of collagen-induced arthritic models, gene expression studies using RT-PCR, affinity purification of recombinant proteins, production and purification of monoclonal and polyclonal antibodies, in-vivo and in-vitro functional studies and humanization of the selected antibodies against sIL-6R and sGP130.

2. Design and recombinant expression of EBOV-GP (Ebola glycoprotein), Protein A, G and L and preparation of affinity columns for purification of monoclonal antibody for diagnostic use

Contents: Cloning, expression and purification of EBOV-GP, Protein A, G and L in E.coli. System, generation of affinity columns using various coupling strategies for purification of monoclonal and polyclonal antibodies.

3. Development of hybrid vectors with intein-based dual tags

Contents: Preparation of chitin binding domains with intein based tags using Gibson Assembly methodology.

Seminar: Stempeutics, Shirdi Sai Baba Cancer Hospital, Manipal, Karnataka, India

Hematopoietic Stem Cells & their Ex Vivo Expansion

Seminar: Convention Centre, Manipal University, Manipal, Karnataka, India

Second annual meeting of Society of Biological Chemists (India) Coastal Karnataka Chapter

Seminar: Indian Institute of Information Technology, Allahabad, Uttar Pradesh, India

Third National Science Conclave- A congregation of Nobel Laureates, supported by MHRD and DST- Govt. of India

Poster Presentation: Amity University, Noida

Biodegradation of Xenobiotics” in Indo-Italian Workshop on Bacteria and Fungi for Environmental Sustainability

Post graduate thesis: April, 2014 - September, 2014

Bhat Biotech India (P) Ltd., Electronics City, Bengaluru, Karnataka, India

Development of Methods for Evaluation of Monoclonal Antibodies against Proteins involved in Rheumatoid Arthritis

Under graduate thesis: March, 2012 - June, 2012

Center for Genetic Disorder, Faculty of Science, Banaras Hindu University, Varanasi, India Profiling of Exon 14A of Factor VIII gene in North Indian Haemophilic-A Population

Bioinformatics Centre: July 29, 2011 – July 31, 2011

Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

Training on Principles, Techniques and Applications of Bioinformatics

Center for Genetic Disorder, Faculty of Science: June 1, 2011 - July 15, 2011 Banaras Hindu University, Varanasi, India

Molecular Analysis of Haemophilia-A factor VIII gene in Sir Sunderlal Hospital, Institute of Medical Sciences, B.H.U.

Department of Microbiology, Institute of Medical Sciences: May 1, 2010 - May 31, 2010 Banaras Hindu University, Varanasi, India

Summer Training Report on Pathogenic Isolation Using Microbial and Molecular Techniques

I hereby declare that the information furnished above is true to the best of my knowledge and belief.

Date: 24-08-2024

Curriculum Vitae of Varsha Ranjan