Summary
Overview
Work History
Education
Certification
Projects
References
Awards
Timeline
Generic

Vijaya Ishwar Tashildar

Summary

Bioprocess Technology M.Tech graduate with 4 years of industrial experience in downstream process development. Specialized in scale-down model validation, resin lifetime studies, and virus clearance. Successfully transferred technology for monoclonal antibody scale-up from CHO cells. Experience in developing processes for monoclonal antibodies, microbial proteins, peptides, and plasmid DNA.

Overview

8
8
years of professional experience
1
1
Certification

Work History

Senior Research Associate

CuraTeq Biologics Pvt. Ltd.
Hyderabad
05.2024 - Current
  • Executed late-stage R&D activities, including scale-down model validation and resin lifetime studies.
  • Managed team performance, prepared GANTT charts, and trained new employees for timely execution.
  • Developed protocols and reports for late-stage activities in compliance with regulatory standards.
  • Coordinated human and material resources to achieve project objectives effectively.
  • Planned and managed workflows while motivating and guiding professional and support staff.
  • Oversaw technology transfer processes for continuous manufacturing advancements.

Senior Research Associate

Syngene International Limited
Bangalore
08.2021 - 04.2024
  • In-vitro synthesis (IVT) of mRNA and development of purification process.
  • Scale down modelling of downstream process for virus clearance studies of mAbs.
  • Platform process development for plasmid DNA purification and scaling up to 50 L.
  • Process Development for mAb purification with >99% purity and scale up to 50 L.
  • Intensive experience in execution of resin life cycle study for mAbs.
  • Performing lab scale consistency batches and Technology transfer batches and scalability evaluation.
  • Provide training and guidance to junior team members.
  • Technical expertise in Chromatography techniques like Ion exchange chromatography, Affinity chromatography, hydrophobic interaction chromatography, Gel filtration and Multimodal chromatography.
  • Brief experience in resin life cycle study and resin screening studies.
  • Membrane chromatography techniques like ProteinA (using Fibro prismA), and AEX (using NatrixQ, polisherST and MustangQ).
  • Handling and packing of Hiscale, Omnifit, Quickscale and BPG 140 columns.
  • Operation of chromatography systems such as AKTA Pure, AKTA Pilot using UNICORN software.
  • Hands on experience on processes like Depth filtration (screening and sizing) and Tangential flow filtration with hollow fibers and flat sheet membrane cassettes using manual and automated TFF systems.
  • Microfiltration and Nanofiltration for removal of microbial cells and viruses respectively.
  • Qualitative and Quantitative techniques of analysis like SDS-PAGE, Agarose gel electrophoresis, UV-Visible and Nanodrop spectrophotometer, Assay- Bradford and BCA assay.
  • Generated comprehensive documents including BPR, Project approach document report, Tech transfer documents and reviewing technical documents.
  • SOP, IOP, EOP and BPR preparation.
  • SPOT AWARD - In recognition of completing deliverables ahead of schedule with professionalism and creating reputation with client.

Intern

Novozymes South Asia Pvt. Ltd.
06.2021 - 08.2021
  • Intern at Application development- Oils and Fats: Enzyme immobilization and enzyme kinetic study.

Intern

QbD Purple Advanced Technologies (QPAT) Ltd.
07.2019 - 10.2019
  • Intern at Technology Translation Center: Work on 'Extraction and improvement of proteins from seeds and oilseed meals'.

Intern

Biological E Ltd.
05.2017 - 06.2017
  • Intern at Biological E Ltd. in Process Development Department - This training was based on qualitative and quantitative analysis of in process sample for proteins, carbohydrate and nucleic acid content.

Education

Master of Technology - Bioprocess Technology

Institute of Chemical Technology
Mumbai
01.2020

Bachelor of Engineering -

KIT's, College of Engineering
Kolhapur, Maharashtra
01.2018

Certification

  • Chromatographic Techniques for Characterization of Bio therapeutics, Venture Center, Pune, 2020
  • Chemical Safety and Risk Management, ICT Mumbai, 6 months, 2018
  • Orientation to Chemical Security Risk Management, SANDIA National Lab, USA, 2018

Projects

M.Tech - Bioprocess Technology, Utilization of industrial waste for production of lipopeptide based surfactant, HOD- Prof. A.P. Pratap, Oils, Oleo Chemicals & Surfactants Technology, Development of intensified process for production of lipopeptide based surfactant 'Surfactin' by fermentation using agro-industrial waste as substrate. B.E - Biotechnology Engineering, Bio-sorption of heavy metals from waste water using low-cost adsorbent and study of its sorption kinetics, Mrs. M. G. Mulgund, Development of Batch and Column process and parameter optimization study to increase the removal of heavy metals using adsorptive technique.

References

  • Mr. Rutuparna P. Karkare, Assistant Professor, Biotechnology, KIT's College of Engineering, Kolhapur, +919404257540, karkare.rutuparna@kitcoek.in
  • Prof. Amit P. Pratap, HOD- Oils, Oleo Chemicals & Surfactants Technology, Institute of Chemical Technology, Mumbai, +919221048682, amitpratap2001@gmail.com

Awards

  • SPOT AWARD, Syngene International Limited, 01/01/22, In recognition of completing deliverables ahead of schedule with professionalism and creating reputation with client.
  • Qualified for GATE Biotech (BT) Examination, 02/01/18
  • Qualified for JNU CEEB Examination, 12/01/18

Timeline

Senior Research Associate

CuraTeq Biologics Pvt. Ltd.
05.2024 - Current

Senior Research Associate

Syngene International Limited
08.2021 - 04.2024

Intern

Novozymes South Asia Pvt. Ltd.
06.2021 - 08.2021

Intern

QbD Purple Advanced Technologies (QPAT) Ltd.
07.2019 - 10.2019

Intern

Biological E Ltd.
05.2017 - 06.2017

Master of Technology - Bioprocess Technology

Institute of Chemical Technology

Bachelor of Engineering -

KIT's, College of Engineering

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