Vinay R S
Bioinformatics Scientist
Bangalore
Summary
As a skilled Bioinformatician, I bring a strong track record in NGS Data Analysis, Pipeline Development, and proficiency in Perl, R Script, and Python for Downstream Analysis. My advanced capabilities in automating cloud computing instances further enhance my ability to deliver exceptional outcomes and surpass expectations.
Overview
9
9
years of professional experience
Work History
Bioinformatics Service Provider
Prenetics HongKong
12.2023 - Current
- Processing and delivering bioinformatics services for clients and internal needs.
- Demonstrated adaptability when faced with changes or challenges in project requirements by quickly adjusting strategies to maintain progress toward desired outcomes.
- Consistently exceeded performance goals by proactively identifying ways to exceed expectations in delivering services.
- I am collaborating with a team on a supplement development project, where my responsibility involves developing and conducting test runs of samples for the microbiome project, as well as finalizing the pipeline.
- I utilize open-source tools such as Kraken2 and Qiime2 to test samples, compare outputs, and identify the best pipeline for our project. Additionally, I design the pipeline, use Docker for software setup, and employ Snakemake to manage the workflow.
Bioinformatics Scientist
Prenetics Innovation Labs Pvt Ltd
11.2021 - 11.2023
- I am involved in developing and testing bioinformatics pipelines, collaborating with the engineering team to deploy and manage these workflows.
- My work includes partnering with genomic and clinical scientists, as well as software engineers, to create innovative bioinformatics solutions.
- I manage clinical services related to CircleDNA and Circle-Medical products, ensuring delivery to the customer support team.
- For the new product CirclePaw, I curate markers from various databases and design a scoring model using Mendelian inheritance patterns to assign scores.
- Additionally, I develop and test pipelines for gender identification in whole exome sequencing (WES) samples using BAM and VCF files.
Inside Sales Coordinator
Qiagen Bioinformatics
12.2018 - 11.2021
- Worked for Qiagen Bioinformatics products (CLC, IPA, QCI, HGMD)
- By running usage reports to find the usage pattern to help in devising strategies
- Work closely with sales management to inspect sales process quality
- Use of Sales Force Lightning to manage accounts
- Invoicing and report derivation.
Project Assistant (Dept of Biochemistry)
Indian Institute of Science (Bangalore)
01.2018 - 12.2018
- Worked on different projects involving data from Melanoma cancer, Hyperpigmentation, and Gut Microbiome
- Developed Pipelines and analysed sequencing data using RNAseq, microRNA, Variant caller applications
- RNASeq analyis - identified the Differentially expressed genes and found the significance of these genes in the patient data VS treated samples
- Variant calling analysis - identified and annotated Variants (SNP's, Indels)
- Worked extensively on running open source tools like Bowtie, BWA-mem, Tophat,(Sequence alignment softwares) Cufflinks, cuffdiff, DEseq,(RNASeq/Differntial Expression) GATK(variant caller)
- Wrote my own automated scripts and used statistical computation on these pipelines in Perl and R language.
Bioinformatics Analyst
LeucineRichBio Pvt LTD
04.2016 - 01.2018
- Analyzing of many NGS derived project and building a framework of NGS analysis
- Developed Fully automated pipeline for running RNASeq workflow, miRNA using Perl and R scripts
- Deploying AWS instances for automated cloud computing
- Created and managed large Instance's on Amazon Web Server for running large and multiple datasets
- Preprocessing: Quality check - FastQC, Quality improvements through TrimGalore, Trimmomatic
- Alignment tools - BowTie2, BWA-MEM
- Genome Analysis: GATK, Variant annotation, filtration
- Transcriptomic Analysis: Transcript alignment [TopHat], Differential expression [Tuxedo Suite, DESeq, EdgeR], Graphical representations [CummeRbund, GGPlot], Splice variant analysis [MISO, rMATS]
- Exploratory Analysis: Pathway Analysis [KEGG Tools], GSEA, GOSeq, STRING, DAVID, GenePattern
- Denovo Assembly and Annotation [SOAPdenovo, Velvet, IDBA, Abyss etc.].
Trainee Bioinformatics Analyst
LeucineRichBio Pvt LTD
09.2015 - 04.2016
- Learnt about Sanger sequencing, Next Generation Sequencing, Nanopore Sequencing
- Bolted up my programming skills in Perl, R and basic python scripting language
- Enhanced my Linux operating system and command line interface experience and learnt new ways in debugging errors.
Education
Master of Engineering - Bioinformatics
UVCE
Bengaluru, India 04.2001 -
Bachelor of Engineering, India - Information Science And Engineering
Alpha College Of Engineering
Bengaluru, India 04.2001 -
Skills
Perl, Python, R
AWS - EC2,S3
Docker, Snakemake
Angular, Html, Css
Windows, MacOS, Ubuntu(Linux)
Frame Work execution
Data visualization, Automation, Algorithm writing
Designing workflow, Handling Resources, Time Management
Goals and Solution oriented
NGS Data Analysis(RNASeq, miRNA, WES, WGS)
Developing and Testing New Pipelines
Downstream Analysis
Microarray Analysis
Network Analysis
Docking Studies
Variant Calling
Micorbiome
Educational Projects
- Identifying the Novel Drug leads of REM Sleep disorder using in-silico method
Identifying the Novel Drug leads of REM Sleep disorder using in-silico method. Creating 3D structure of genes causing REM sleep disorder, docking studies with
many Phyto compounds, and evaluating the docked compounds ADME studies.
- New Approach to Quantification of Privacy on Social Network Sites
New Approach to Quantification of Privacy on Social Network Sites. We present a new metric to quantify privacy, based on probability and entropy theory. We
define the leaked privacy value as the amount of knowledge adversaries can learn about a problem of interest.
References
- Nagasuma Chandra, Professor, Biochemistry Dept, Indian Institue of Science, nchandra@iisc.ac.in
- Dr. Gopalakrishna Kallapura, Lead Microbiome Domain, Leucine Rich Bio Pvt Ltd, gkallapura@leucinerichbio.com
Timeline
Bioinformatics Service Provider
Prenetics HongKong
12.2023 - Current
Bioinformatics Scientist
Prenetics Innovation Labs Pvt Ltd
11.2021 - 11.2023
Inside Sales Coordinator
Qiagen Bioinformatics
12.2018 - 11.2021
Project Assistant (Dept of Biochemistry)
Indian Institute of Science (Bangalore)
01.2018 - 12.2018
Bioinformatics Analyst
LeucineRichBio Pvt LTD
04.2016 - 01.2018
Trainee Bioinformatics Analyst
LeucineRichBio Pvt LTD
09.2015 - 04.2016
Master of Engineering - Bioinformatics
UVCE
04.2001 -
Bachelor of Engineering, India - Information Science And Engineering
Alpha College Of Engineering
04.2001 -