Summary
Overview
Work History
Education
Skills
Websites
Educational Projects
References
Timeline
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Vinay R S

Bioinformatics Scientist
Bangalore

Summary

As a skilled Bioinformatician, I bring a strong track record in NGS Data Analysis, Pipeline Development, and proficiency in Perl, R Script, and Python for Downstream Analysis. My advanced capabilities in automating cloud computing instances further enhance my ability to deliver exceptional outcomes and surpass expectations.

Overview

9
9
years of professional experience

Work History

Bioinformatics Service Provider

Prenetics HongKong
12.2023 - Current
  • Processing and delivering bioinformatics services for clients and internal needs.
  • Demonstrated adaptability when faced with changes or challenges in project requirements by quickly adjusting strategies to maintain progress toward desired outcomes.
  • Consistently exceeded performance goals by proactively identifying ways to exceed expectations in delivering services.
  • I am collaborating with a team on a supplement development project, where my responsibility involves developing and conducting test runs of samples for the microbiome project, as well as finalizing the pipeline.
  • I utilize open-source tools such as Kraken2 and Qiime2 to test samples, compare outputs, and identify the best pipeline for our project. Additionally, I design the pipeline, use Docker for software setup, and employ Snakemake to manage the workflow.

Bioinformatics Scientist

Prenetics Innovation Labs Pvt Ltd
11.2021 - 11.2023
  • I am involved in developing and testing bioinformatics pipelines, collaborating with the engineering team to deploy and manage these workflows.
  • My work includes partnering with genomic and clinical scientists, as well as software engineers, to create innovative bioinformatics solutions.
  • I manage clinical services related to CircleDNA and Circle-Medical products, ensuring delivery to the customer support team.
  • For the new product CirclePaw, I curate markers from various databases and design a scoring model using Mendelian inheritance patterns to assign scores.
  • Additionally, I develop and test pipelines for gender identification in whole exome sequencing (WES) samples using BAM and VCF files.

Inside Sales Coordinator

Qiagen Bioinformatics
12.2018 - 11.2021
  • Worked for Qiagen Bioinformatics products (CLC, IPA, QCI, HGMD)
  • By running usage reports to find the usage pattern to help in devising strategies
  • Work closely with sales management to inspect sales process quality
  • Use of Sales Force Lightning to manage accounts
  • Invoicing and report derivation.

Project Assistant (Dept of Biochemistry)

Indian Institute of Science (Bangalore)
01.2018 - 12.2018
  • Worked on different projects involving data from Melanoma cancer, Hyperpigmentation, and Gut Microbiome
  • Developed Pipelines and analysed sequencing data using RNAseq, microRNA, Variant caller applications
  • RNASeq analyis - identified the Differentially expressed genes and found the significance of these genes in the patient data VS treated samples
  • Variant calling analysis - identified and annotated Variants (SNP's, Indels)
  • Worked extensively on running open source tools like Bowtie, BWA-mem, Tophat,(Sequence alignment softwares) Cufflinks, cuffdiff, DEseq,(RNASeq/Differntial Expression) GATK(variant caller)
  • Wrote my own automated scripts and used statistical computation on these pipelines in Perl and R language.

Bioinformatics Analyst

LeucineRichBio Pvt LTD
04.2016 - 01.2018
  • Analyzing of many NGS derived project and building a framework of NGS analysis
  • Developed Fully automated pipeline for running RNASeq workflow, miRNA using Perl and R scripts
  • Deploying AWS instances for automated cloud computing
  • Created and managed large Instance's on Amazon Web Server for running large and multiple datasets
  • Preprocessing: Quality check - FastQC, Quality improvements through TrimGalore, Trimmomatic
  • Alignment tools - BowTie2, BWA-MEM
  • Genome Analysis: GATK, Variant annotation, filtration
  • Transcriptomic Analysis: Transcript alignment [TopHat], Differential expression [Tuxedo Suite, DESeq, EdgeR], Graphical representations [CummeRbund, GGPlot], Splice variant analysis [MISO, rMATS]
  • Exploratory Analysis: Pathway Analysis [KEGG Tools], GSEA, GOSeq, STRING, DAVID, GenePattern
  • Denovo Assembly and Annotation [SOAPdenovo, Velvet, IDBA, Abyss etc.].

Trainee Bioinformatics Analyst

LeucineRichBio Pvt LTD
09.2015 - 04.2016
  • Learnt about Sanger sequencing, Next Generation Sequencing, Nanopore Sequencing
  • Bolted up my programming skills in Perl, R and basic python scripting language
  • Enhanced my Linux operating system and command line interface experience and learnt new ways in debugging errors.

Education

Master of Engineering - Bioinformatics

UVCE
Bengaluru, India
04.2001 -

Bachelor of Engineering, India - Information Science And Engineering

Alpha College Of Engineering
Bengaluru, India
04.2001 -

Skills

Perl, Python, R

Websites

Educational Projects

  • Identifying the Novel Drug leads of REM Sleep disorder using in-silico method

           Identifying the Novel Drug leads of REM Sleep disorder using in-silico method. Creating 3D structure of genes causing REM sleep disorder, docking studies with   

           many Phyto compounds, and evaluating the docked compounds ADME studies.

  • New Approach to Quantification of Privacy on Social Network Sites

            New Approach to Quantification of Privacy on Social Network Sites. We present a new metric to quantify privacy, based on probability and entropy theory. We 

define the leaked privacy value as the amount of knowledge adversaries can learn about a problem of interest.

References

  • Nagasuma Chandra, Professor, Biochemistry Dept, Indian Institue of Science, nchandra@iisc.ac.in
  • Dr. Gopalakrishna Kallapura, Lead Microbiome Domain, Leucine Rich Bio Pvt Ltd, gkallapura@leucinerichbio.com

Timeline

Bioinformatics Service Provider

Prenetics HongKong
12.2023 - Current

Bioinformatics Scientist

Prenetics Innovation Labs Pvt Ltd
11.2021 - 11.2023

Inside Sales Coordinator

Qiagen Bioinformatics
12.2018 - 11.2021

Project Assistant (Dept of Biochemistry)

Indian Institute of Science (Bangalore)
01.2018 - 12.2018

Bioinformatics Analyst

LeucineRichBio Pvt LTD
04.2016 - 01.2018

Trainee Bioinformatics Analyst

LeucineRichBio Pvt LTD
09.2015 - 04.2016

Master of Engineering - Bioinformatics

UVCE
04.2001 -

Bachelor of Engineering, India - Information Science And Engineering

Alpha College Of Engineering
04.2001 -

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