Vivek kumar Singh
DEPUTY MANAGER IN PEPTIDE PURIFICATION DEPARTMENT, 11/2023 - Current Aurigene Pharmaceutical Services Limited
Miyapur
Summary
Experienced Team Lead - Purification and HPLC Method Development with over 11 years of expertise in the pharmaceutical industry, specializing in the purification of peptides, oligosaccharides, polysaccharides, lipid molecules, and proteins (up to 3000 Da molecular mass). Proven track record of successfully leading laboratory operations, method development, analytical testing, documentation, and cross-functional coordination.
Overview
14
14
years of professional experience
4022
4022
years of post-secondary education
2
2
Certifications
Work History
Deputy manager in Peptide purification Department
Aurigene Pharmaceutical Services Limited
11.2023 - Current
- Managed the purification process of peptide molecules and proteins, ensuring high-quality and reproducible results.
- Specialized in HPLC method development and purification of peptides, oligosaccharides, polysaccharides, lipid molecules, and proteins with molecular masses up to 3000 Da.
- Developed and implemented innovative purification methods using DAC columns (50 mm, 80 mm, 150 mm, 200 mm), significantly enhancing process efficiency.
- Handled internal laboratory operations, ensuring smooth workflow and strict adherence to safety protocols and GMP standards.
- Generated comprehensive peptide material and isolated impurity data, contributing to the precision and accuracy of analytical and research outcomes.
- Interpreted complex molecular data, providing critical insights to support ongoing research and development initiatives.
- Successfully led a team of 4 scientists, fostering a collaborative, high-performance work environment to meet project timelines and quality expectations.
Sinior Research Associate
Jubliant Biosys LTD
11.2019 - 11.2023
- Company Overview: Noida, India
- Developed analytical HPLC methods for new drug products, enhancing the efficiency and reliability of the research and development process.
- Successfully designed and optimized preparative methods for bi-cyclic and tri-cyclic compounds, contributing to advanced compound profiling and purification.
- Implemented preparative HPLC and liquid chromatography techniques for recursion reaction monitoring, ensuring accurate process evaluation.
- Integrated mass spectrometry (MS) and gas chromatography (GC) with preparative workflows to enable comprehensive analytical coverage.
- Developed and validated analytical methods for lipid and peptide molecule analysis and purification, significantly improving data accuracy and reproducibility.
- Noida, India
Senior Research Associate
Piramal Healthcare Ltd
09.2016 - 11.2019
- Company Overview: Ahmedabad
- Ensured the effective purification of various compounds using preparative HPLC techniques to support drug development and research activities.
- Developed and optimized methods for both chiral and achiral compound analysis using normal-phase and reverse-phase preparative HPLC.
- Efficiently managed and operated the UPLC H-Class system equipped with an SQD detector, ensuring high-quality data acquisition and system performance.
- Ahmedabad
officer
LUPIN LTD
05.2015 - 05.2016
- Company Overview: Mandideep, Bhopal (M.P)
- Developed analytical methods for the analysis of antibiotic and cardiovascular drugs, including Ofloxacin, Cefixime, Cephalexin, Cefdinir, Rosuvastatin Calcium, and Atorvastatin Calcium.
- Utilized Gas Chromatography (GC) and Liquid Chromatography (HPLC) systems for qualitative and quantitative analysis, ensuring compliance with regulatory standards.
- Mandideep, Bhopal (M.P)
Chemist
Saurav Chemical Ltd.
07.2011 - 05.2013
- Company Overview: Mohali, Punjab
- Conducted High-Performance Liquid Chromatography (HPLC) for the analysis of Active Pharmaceutical Ingredients (APIs), ensuring product quality and compliance with industry standards.
- Performed detailed chemical analyses to identify the composition and properties of pharmaceutical compounds.
- Executed various wet lab techniques, including water content measurement, Fourier Transform Infrared (FTIR) Spectroscopy, and Ultraviolet-Visible (UV-Vis) Spectroscopy, contributing to comprehensive product testing and quality assurance.
- Mohali, Punjab
Education
Master of Science - Organic Chemistry
Dr. Ram Manohar Lohia Awadh University
Bachelor of Science - Environmental Chemistry and Botany
Dr. Ram Manohar Lohia Awadh University
Faizabad, UPIntermediate -
UP BORD Allhabad
Highschool -
UP BORD Allhabad
Skills
Techniques for protein isolation
Performance improvements
Oligosaccharide and Lipid PurificationDAC Column Packing & OperationScale-Up ProcessesAnalytical Documentation & ComplianceQuality Systems ImplementationCross-Functional Team CoordinationHigh-Throughput Laboratory ManagementCertification
Annual Excellence Award, Aurigene Pharmaceutical Services Limited, 05/01/25, Recognized for exceptional collaboration in the successful purification of 150 grams of peptide, ensuring on-time delivery and meeting project quality standards.
Accomplishments
- Successfully completed 132 purification projects with high efficiency and accuracy.
- Achieved peptide purification up to 20 grams and protein purification up to 3000 grams.
- Specialized in DAC column packing and operation for multiple column sizes (50 mm, 80 mm, 150 mm and 200 mm).
- Effectively handled both small-batch and scale-up purifications, supporting process development and optimization.
- Played a key role in improving the strategic and operational performance of the Quality Department through the development and implementation of standardized quality systems.
Personal Information
Timeline
Deputy manager in Peptide purification Department
Aurigene Pharmaceutical Services Limited
11.2023 - Current
Sinior Research Associate
Jubliant Biosys LTD
11.2019 - 11.2023
Senior Research Associate
Piramal Healthcare Ltd
09.2016 - 11.2019
officer
LUPIN LTD
05.2015 - 05.2016
Chemist
Saurav Chemical Ltd.
07.2011 - 05.2013
Bachelor of Science - Environmental Chemistry and Botany
Dr. Ram Manohar Lohia Awadh University
Highschool -
UP BORD Allhabad
Master of Science - Organic Chemistry
Dr. Ram Manohar Lohia Awadh University
Intermediate -
UP BORD Allhabad