ANJALI SHARMA
Computational Biologist
Hyderabad
Summary
Innovative Computational Biologist with expertise in bioinformatics, systems biology, and molecular modeling for therapeutic target discovery. Skilled in integrating multi-omics data, network pharmacology, and drug design to accelerate precision medicine. Proficient in computational biology workflows, combining Python/R-based analysis, molecular docking, and ADMET modeling to identify lead compounds with clinical relevance. Experienced with in silico and experimental methods, including PCR, Western blotting, and cell culture.
Overview
2
2
years of professional experience
Work History
Research Intern
Indian Institute Of Technology, Hyderabad
11.2024 - 06.2025
- Designed and executed computational biology project to identify 20k + natural phytoconstituent inhibitors targeting key genes involved in castration-resistant prostate cancer (CRPC).
- Applied network pharmacology and systems biology approaches using Cytoscape and CytoHubba to construct and analyze protein–protein interaction networks.
- Conducted >20k molecular docking simulations (PyRx / AutoDock), achieving >30% improvement in predicted ligand–receptor binding efficiency.
- Performed drug-likeness and ADMET filtering using Lipinski’s Rule, SwissADME, pKCSM, and ProTox to identify compounds with optimal pharmacokinetic profiles.
- Carried out PASS and toxicity prediction to evaluate biological activity with
- Integrated results with data analysis pipelines and computational modeling workflows using Python-based scripts for compound prioritization.
- Validated in silico findings through PCR, gel electrophoresis, and western blotting experiments.
- Collaborated with bioinformatics researchers to enhance data reproducibility, visualization, and model validation.
Winter Internship
DRDO, Delhi
12.2023 - 03.2024
- Conducted computational modeling and simulation for nano-device patterning using photolithography process optimization; achieved 20% higher resolution consistency.
- Contributed to cross-functional collaboration with materials scientists on image analysis and data quantification for nano-bio interface studies.
Thesis Project
Delhi Technological University
01.2023 - 01.2024
- Performed network pharmacology and molecular docking to study the anti-tuberculosis properties of Morinda citrifolia, identifying multiple bioactive lead compounds.
- Utilized Biovia Discovery Studio, Cytoscape, STRING, SwissTargetPrediction, and PubChem for computational modeling and drug–target interaction studies.
- Implemented multi-omics integration and data visualization pipelines for pathway analysis and compound validation.
Education
Master of Science - Biotechnology
Delhi Technological University
05.2024
Bachelor of Science - Biotechnology
Chandigarh University
05.2022
Class XII (CBSE) - undefined
Army Public School
Pathankot01.2019
Class X (CBSE) - undefined
Army Public School
Nasirabad01.2017
Skills
Wet Lab: PCR, Gel Electrophoresis, Western Blotting, Cell Culture (bacterial & mammalian), Molecular Imaging, Chromatography
Computational Tools: PyRx (AutoDock), Biovia Discovery Studio, Cytoscape, STRING, SwissTargetPrediction, PubChem,Protein Data bank
Techniques: Molecular Docking, Drug Design, Network Pharmacology, SEM, FTIR, Ultracentrifugation
Soft Skills: Scientific Writing, Data Interpretation, Team Collaboration, Research Presentation
Accomplishments
- Secured 40th Rank in Delhi Technological University Entrance Exam
- Secured 3rd Rank in Punjab University Entrance Exam
- Secured 25th Rank in Delhi University Entrance Exam
LEADERSHIP & EXTRACURRICULARS
- Secured second place in inter-department basketball competition at IIT hyderabad(2025).
- Head Girl (Class XII), Class Representative (Undergraduate)
- Captain of Basketball Team at DTU
- DTU Sports Achievements:
1st place, Inter-University Basketball (DTU, 2024)
2nd place, Inter-University Basketball (DTU, 2023)
3rd place, IIT Kanpur Tournament (2022)
PUBLICATIONS & CONFERENCES
- Exploring Potential of Bacopa monnieri Against B19V-Induced Erythema Infectiosum: An In Silico Approach — JNU International Conference on Intelligent Computing and Communication Techniques
Timeline
Research Intern
Indian Institute Of Technology, Hyderabad
11.2024 - 06.2025
Winter Internship
DRDO, Delhi
12.2023 - 03.2024
Thesis Project
Delhi Technological University
01.2023 - 01.2024
Class XII (CBSE) - undefined
Army Public School
Class X (CBSE) - undefined
Army Public School
Master of Science - Biotechnology
Delhi Technological University
Bachelor of Science - Biotechnology
Chandigarh University