ANNARAM THIRUPATHI
Hyderabad
Summary
Innovative and skilled synthetic organic and medicinal chemist with extensive experience in both academic and industrial research to synthesize biorelevant chemical scaffolds.
Overview
5
5
years of professional experience
Work History
Research Scientist, Medicinal Chemistry
Sai Schrödinger Research Laboratories
Hyderabad
09.2024 - Current
- Proficient in the development and implementation of cost saving protocols to synthesize novel chemical entities with desired purity for clinical studies by using the state of the art purification techniques.
- Able to collaborate with cross-functional teams, including biologists and pharmacologists.
Post-doctoral Researcher
Kyung Hee University
Yongin
01.2022 - 08.2024
- Experienced in developing new strategies for the construction of useful heterocyclic compounds by organo photoredox catalysis
Associate Scientist
Aragen Life Sciences (Formerly Known as GVK Biosciences Pvt Ltd)
Hyderabad
07.2019 - 12.2021
- Designed and developed the new protocols for the synthesis of diverse range of mono, di phosphonate esters & phosphonic acids
- Experienced in carbohydrate chemistry, click chemistry, peptide bond forming reactions and construction of various types C−C & C−N bond forming reactions
- Proficient in writing the work progress reports and final reports, Led the team consisting of three members (FTE's)
- Knowledge in safety protocols, Proper handling of chemical reagents, be able to maintain a safe and clean laboratory
Education
Ph.D - Synthetic Organic Chemistry
National Institute of Science Education and Research (NISER)
Bhubaneswar, Odisha, India06.2019
Master of Science (M.Sc) - Organic Chemistry
Osmania University
Hyderabad, Telangana, India06.2011
Bachelor of Science (B.S.) - Chemistry
Kakatiya University
Warangal, Telangana, India05.2009
Skills
- Medicinal Chemistry
- Multi step synthesis
- Organic and Organometallic Chemistry
- Heterocyclic Chemistry
- Photoredox catalysis
- Interpretation of analytical data
- Purification Techniques
- Problem solving & Trouble shooting the critical reactions
- Team Leadership
Publications
- Iron Catalysis of C(sp3)-H Azidation Using a Heteroarene Radical Cation Strategy, A. Y. Ji, Annaram Thirupathi, J. Y. Hwang, Y. Kim, G. Han, K-H. Ahn, K. Kang, and E. J. Kang., Org. Lett., 2023, 25, 1541
- 2,3-Difunctionalized Benzo[b]thiophenes Novel Scaffolds possessing potent Anti-angiogenic Property, H. Singh#, Annaram Thirupathi#, B. Das#, M. Janni, R.Kumari, S. K Singh, M. Rashid, M. Wahajuddhin, Balamurali.M.M., K. Jagavelu and S. Peruncheralathan., J. Med. Chem., 2022, 65, 120
- Triflic Acid Mediated N-Heteroannulation of β-Anilino-β(methlthio)acrylonitriles: A Facile Synthesis of 4-Amino-2(methlthio)quinolines, D. Bandyopadhyay, Annaram Thirupathi, D. Radhakrishnan, A. Panigrahi, and S. Peruncheralathan., Org. Biomol. Chem., 2021, 19, 8544
- Chemoselective Ullmann Reaction of α-Trisubstituted Thioamides: Synthesis of Novel 2-Iminobenzothiolanes, A. Bhattacharya, Annaram Thirupathi, P. Natarajan and S. Peruncheralathan., ACS Omega, 2021, 6, 21169
- Nickel Catalyzed Site Selective C-H Functionalization of α-Arylthioamides, D. Bandyopadhyay#, Annaram Thirupathi#, N. M. Dhage, N. Mohanta, and S. Peruncheralathan., Org. Biomol. Chem., 2018, 16, 6405
- Copper Catalyzed Intramolecular N-Arylation of Ketene Aminals at Room Temperature: Synthesis of 2-Amino-3-cyanoindoles, Annaram Thirupathi, M. Janni and S. Peruncheralathan., J. Org. Chem, 2018, 83, 8668
- Chemoselective Ullman Coupling at Room Temperature: Facile access to 2-amino benzo[b]thiophenes, M. Janni, Annaram Thirupathi, S. Arora and S. Peruncheralathan., Chem. Comm., 2017, 53, 8439
Awards and scholarships
- 12/20, Outstanding Achiever, Aragen Life Sciences, Hyderabad
- 08/14, Senior Research Fellowship, National Institute of Science Education and Research (NISER)-Bhubaneswar
- 02/12, Qualified Graduate Aptitude Test in Engineering (GATE)
- 12/11, Qualified NET for Junior Research Fellowship conducted by CSIR-UGC
Languages
Telugu
First Language
English
Proficient (C2)
C2
Hindi
Advanced (C1)
C1
Timeline
Research Scientist, Medicinal Chemistry
Sai Schrödinger Research Laboratories
09.2024 - Current
Post-doctoral Researcher
Kyung Hee University
01.2022 - 08.2024
Associate Scientist
Aragen Life Sciences (Formerly Known as GVK Biosciences Pvt Ltd)
07.2019 - 12.2021
Ph.D - Synthetic Organic Chemistry
National Institute of Science Education and Research (NISER)
Master of Science (M.Sc) - Organic Chemistry
Osmania University
Bachelor of Science (B.S.) - Chemistry
Kakatiya University
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