Arundhati Das

Molecular biologist with 7+ years of expertise in RNA biology, focusing on circular RNAs, gene regulation, and muscle differentiation. Skilled in RNA sequencing, ddPCR, RT-qPCR, cell culture, transfection, and molecular cloning. Authored publications in top-tier journals such as Frontiers in Molecular Biosciences and Nucleic Acids Research. Actively pursuing R&D opportunities in RNA therapeutics and molecular biology within biotechnology.

• 2017 Qualified CSIR-UGC NET for Junior Research Fellow and Lectureship (NET-JRF).
• 2015 CSIR-UGC National Eligibility Test for Lectureship (NET-LS).
• 2015 Graduate Aptitude Test in Engineering (GATE) in Life Science.
• 2013 Qualified Institute of Mathematics and Application (IMA) scholarship.
• 2012 P.G. Merit Scholarship from the University Grant Commission for the first Rank in graduation degree.

Oral and poster presentation

• 1. Delivered an oral presentation entitled "Role of sub-cellular localization of circular RNAs in muscle cell differentiation" at the 11th RNA Group Meeting, NCCS, Pune, on December 1st - 3rd, 2022
• 2. Presented a poster entitled 'Role of circular RNAs in skeletal muscle aging' at SAC-2021 in July 2021, ILS, Bhubaneswar
• 3. Presented a poster entitled "Nuclear and cytoplasmic localization of circular RNAs in myoblasts" at SAC-2019 on July 16, 2019, ILS, Bhubaneswar
• Workshops and conferences attended
• 4. Attended the virtual Ensembl Browser course from July 19th to 30th, 2021, organized by EMBL-EBI
• 5. Attended the “Emerging Trends in Biological Sciences and Research” symposium, ILS, Bhubaneswar, India, March 18th-19th, 2019
• 6. Attended the symposium on “Next Generation Sequencing Technologies: Challenges and Opportunities,” Institute of Life Sciences, Bhubaneswar, India, March 7, 2019
• 7. Attended the 10th RNA Group Meeting, RGCB, Trivandrum, Kerala, March 2nd - 4th, 2019

Outreach activities

• 8. Participated in the Science Outreach Program on National Science Day, February 28, 2019, at NC College, Jajpur, Odisha, India
• 9. Participated in a science outreach program on September 12, 2018, at Government Girls' High School, Jajpur, Odisha, India

• Title - Identification and characterization of functional circular RNAs in skeletal muscle.
• Supervisor- Dr. Amaresh C. Panda
• Research Area- Circular RNAs (circRNAs) are produced by back-splicing, belong to the non-coding RNA class, and are known to regulate gene expression by interacting with miRNAs and RNA binding proteins (RBPs). We have identified hundreds of functional circRNAs expressed in aging mice skeletal muscle and C2C12 skeletal muscle cell line by high-throughput RNA sequencing. Identification of one abundant circRNA, circNfix, in mice skeletal muscle is found to regulate muscle differentiation by promoting Mef2c expression through sponging of miR-204-5p. Further, circRNA sequencing in C2C12 identified differentially expressed circCebref as a positive regulator of myotube formation by interacting with miR-181-5p and upregulating the expression of its downstream mRNA target, Pofut1.

• PubMed: https://www.ncbi.nlm.nih.gov/myncbi/collections/mybibliography/
• Web of Science: https://www.webofscience.com/wos/author/record/KDN-4627-2024
• Google Scholar: https://scholar.google.com/citations?user=qiLobhMAAAAJ&hl=en&oi=ao
• ORCID : 0000-0003-3251-4842
• Scopus ID : 57209556826 (https://www.scopus.com/authid/detail.uri?authorId=57209556826)
• Researchgate: https://www.researchgate.net/profile/Arundhati-Das-6
• LinkedIn: https://www.linkedin.com/feed/?trk=guest_homepage-basic_google-one-tap-submit

• Amaresh C. Panda, Scientist E, and Wellcome Trust/DBT Intermediate Fellow, email: amaresh.panda@ils.res.in, contact: +91 674 230 4314, +91 824 913 8832, Institute of Life Sciences, Bhubaneswar, Odisha, India
• Mamoni Dash, Scientist C, and Ramalingaswami Fellow, email: mamoni.dash@ils.res.in, contact: +91 674 230 4333, Institute of Life Sciences, Bhubaneswar, Odisha, India
• Sandeep K. Panda, Assistant Professor, email: sandeep.panda@kiitbiotech.ac.in, contact: +91 943 811 1772, School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Bhubaneswar, Odisha, India