Summary
Overview
Work History
Education
Skills
Accomplishments
Certifications And Workshops
Languages
Extracurricular Activities
Hobbies and Interests
Internships And Training
Research
Timeline
Generic

Shaikh Ashraf

Navi Mumbai

Summary

Bioprocess Technologist with strong background in microbial research and analytical techniques. Proven ability to develop and optimize bioprocesses for industrial applications. Committed to leveraging biotechnology innovations to improve efficiency and productivity.

Overview

4
4
years of professional experience

Work History

Senior Research Associate

Syngene International Ltd.
Hyderabad
01.2021 - Current
  • NCE documentation and bioanalytical reporting.
  • Analytical method development, quantitative, and qualitative analysis of drug molecules using LC-MS/MS.
  • LC-MS/MS-related troubleshooting.
  • Expertise in instrumentation handling, including Sciex Triple Quad 5500 and 6500 LC-MS/MS integrated with Shimadzu UFLC, ensuring precise bioanalytical measurements, and high-performance liquid chromatography operations.
  • Ensured accurate calibration of laboratory instruments, including pH meters, and weighing machines, for precise measurements.
  • In vitro ADME-DMPK exposure: Phys-Chem property studies (kinetic solubility, thermodynamic solubility, log D), metabolic stability studies (liver microsomes and hepatocyte). Permeability studies (MDCK MDR1 and Caco2), enzyme kinetics and inhibition studies (drug-drug interaction (DDI) and time-dependent inhibition (TDI) assays), chemical stability, and formulation analysis.

Education

Master of Technology - Bioprocess Technology

Institute of Chemical Technology
Mumbai
01.2022

Bachelor of Engineering - Biotechnology

MGM College of Engineering & Technology
Navi Mumbai
01.2019

Skills

  • Bioprocess techniques: upstream and downstream processing
  • Enzymatic assays
  • Protein purification
  • Analytical methods: HPLC (RP and NP)
  • LC-MS
  • UV-Vis spectrophotometry
  • SDS PAGE
  • TLC
  • Microbiological techniques: mammalian and microbial cell culture
  • Gram staining
  • ELISA
  • PCR and RT-PCR
  • Data analysis: R programming
  • Advanced MS Excel, MS PowerPoint

Accomplishments

  • Qualified GAT-B, AIR 95 (General Category), 2020
  • Third Place in School Chess Competition

Certifications And Workshops

  • Filtration Workshop, Biozeen, Bangalore, Vaccine production via tangential flow filtration.
  • Biosimilars Workshop, ICT, Mumbai, Protein aggregation analysis using dynamic light scattering.
  • Safety & Risk Management Course, ICT, Mumbai, 2020 - 2022

Languages

  • English
  • Hindi
  • Urdu

Extracurricular Activities

Poster Presentation, Biotechnology Conclave, ICT, Mumbai, 2019 Bioplastics Workshop, Student Outreach Program, Biopharma, Mumbai, 2019

Hobbies and Interests

  • Chess
  • Football

Internships And Training

  • MICROCHEM SILLIKER PVT. LTD, Navi Mumbai, 12/18, 01/19, Conducted food compositional analysis using HPLC, LC-MS, flame spectrophotometry., Performed microbial testing with gram staining, streaking, and isolation techniques.
  • Explore & Understand DNA, BioEra Training, Pune, 08/18, Isolated & purified DNA using SDS cell lysis method., Conducted size analysis via SDS PAGE.

Research

  • M.Tech Research Project, Institute of Chemical Technology, Extraction of bioactive compounds from green macroalgae & characterization. Conducted compound extraction & purification for pharmaceutical applications. Utilized high-pressure reactors & chromatography techniques for molecular identification.
  • B.Tech Research Project, MGM College of Engineering & Technology, Microbial Production of Plastics Using Agro-Waste. Developed sustainable bio-plastic alternatives using microbial fermentation. Optimized bioprocess conditions under Dr. Sandhya Agarwal.

Timeline

Senior Research Associate

Syngene International Ltd.
01.2021 - Current

Master of Technology - Bioprocess Technology

Institute of Chemical Technology

Bachelor of Engineering - Biotechnology

MGM College of Engineering & Technology

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Shaikh Ashraf