Dr. Dharmendra Kumar Khatri

A dedicated Associate Professor with a strong record of fostering academic excellence, research innovation, and student engagement. Known for delivering dynamic lectures, leading thought-provoking discussions, and enhancing curriculum development, I excel in research methodology, strategic planning, and interdisciplinary collaboration. With a proven track record in program enhancement and innovative teaching methods, I am committed to optimizing the student learning experience through diverse pedagogical approaches. Highly organized, adaptable, and driven, I thrive in high-pressure academic environments, leveraging exceptional presentation, research, and communication skills to inspire intellectual growth and professional development.

Neuroscience: MicroRNAs: Theranostic: Multi-omics: Parkinson's Disease: Nose-to-brain delivery

We are trying to understand the α-synuclein dysregulation at post-transcriptional (miRNA’s) and post-translational levels (Phosphorylation), leading to its overexpression and transition to toxic oligomeric form in Parkinson’s disease (PD). A multidisciplinary approach is employed to investigate the cellular and molecular mechanism underlying the pathogenic degeneration of specific neuronal populations in the brain using various bioinformatics, in-vitro, and in-vivo models. In addition, the pharmacological screening of novel molecules isolated from plant sources or synthetic congeners, and targeted drug delivery systems for their improved neuroprotective and neuronal regeneration properties carried out using cellular and animal models.

0000-0001-7066-7706

Publications: >128

Books: 2

Book Chapters: >20

Patents: 07 (Granted)

Process scale-up, validation, preclinical and safety evaluation of intravaginal metformin hydrochloride thermosensitive gel in polycystic ovary syndrome, Indian Council of Medical Research (ICMR), Govt. of India, Co-Investigator (Co-PI), 4,054,628.00, Ongoing To Develop Parkinson's Disease and a Glioblastoma brain tumor model in rodents using Stereotaxic, Sail Life Sciences, Hyderabad, India (Private), Principal Investigator (PI), 631714.00, Completed

1. Listed in World top 2 % Scientist list released by Stanford 2024.

2. Admitted as Associate Fellows of Telangana Academy of Sciences, India for the years 2022 for the recognition of contributions to Science & Technology

3. Excellent Oral Presentation award for the oral presentation entitle “S1PR2 inhibition modulates microglial activation via Akt-p53-TIGAR pathway in diabetic rats to improve cognition” at 12th Seoul International Congress of Endocrinology and Metabolism, in conjunction with the 43rd Annual Scientific Meeting of the Korean Endocrine Society (KES). at Grand Walkerhill Seoul in Korea from April 11-13, 2024.

4. Awarded First position for Dr. P. D. Patil Best Thesis Award 2023, in the subject category M. Pharmacy-Pharmacology for the thesis entitled “Role of F-actin-mediated endocytosis and exercise in mitochondrial transplantation in an experimental Parkinson’s disease mouse model” instituted by Dr. D. Y. Patil Unitech Society’s, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune-411018, Maharashtra, India on 01 of April 2024.

5. Best Poster Award for the poster presentation entitled "Neuroprotective role of Dimethyl Fumarate (DMF) through enhanced mitophagy via Nrf2/NRF1/BNIP3/PINK1 axis in MPP+ induced Parkinson’s Disease mice model” at 4th International Conference of Korean Movement Disorder Society (ICKMDS 2023) held from December 1-2, 2023, Seoul, Korea

6. Selected for the Japanese Neuroscience Society Travel Award to attend and give oral presentation at the 46th Annual Meeting of Japanese Neurosciences Society (JNS), held in Sendai, Miyagi pref., Japan from August 1st to August 4th, 2023.

7. Selected for the Lalitha and Ravindra Nath International Travel Award from Indian Academy of Neuroscience (IAN) to attend and present a poster at the International Society for Neurochemistry (ISN) and the American Society for Neurochemistry (ASN) held 04–08 August 2019 in Montréal, Canada.

8. Selected as Indian Ambassador on behalf of International Society of Neurochemistry (ISN) consequently for the year 2019-21 and 2022-24.

9. Selected as Next Generation Young Neuroscientist for Basic Science Summer School held at the Osaka University Nakanoshima Center in Osaka, Japan from August 3-4, 2018.

10. Awards for investigators from developing countries in the amount of US$ 750 International Parkinson’s Disease Foundation and the Association of Parkinsonism and Related Disorders for poster presentation in XXIII World Congress on Parkinson’s Disease and Related Disorders, 19 - 22 August 2018 in Lyon, France

11. Appreciation award in Research Contribution during 2017-18 at Dr D.Y. Patil Institute of Pharmaceutical Sciences & Research, Pimpri, Pune, India

12. Awards for investigators from developing countries in the amount of US$ 750 by Melvin Yahr International Parkinson’s Disease Foundation and the Association of Parkinsonism and Related Disorders for poster presentation in XXII World Congress on Parkinson’s Disease and Related Disorders, 12-15 November 2017 at Ho Chi Minh City, Vietnam.

13. Awards for investigators from developing countries in the amount of US$ 1000 by Melvin Yahr International Parkinson’s Disease Foundation and the Association of Parkinsonism and Related Disorders for oral presentation in XX World Congress on Parkinson’s Disease and Related Disorders, 8-11 December 2013 at Geneva, Switzerland.

14. Travel grant (Partial) from Council of Scientific & Industrial Research (CSIR), Govt. of India for oral presentation in XX World Congress on Parkinson’s Disease and Related Disorders, 8-11 December 2013 at Geneva, Switzerland.

15. Travel grant (Partial) from The Centre for International Co-operation in Science (CICS-INSA) for presenting research paper at at 7th Congress of the International Society of Nutrigenetics/ Nutrigenomics (ISNN), October 5–8, 2013, Quebec City, Quebec, Canada.

16. Travel grant from Indian Council of Medical Research (ICMR) for presenting research paper at “3rd World Parkinson Congress (WPC 2013) Palais des congres. Montreal, Québec, Canada, from 1-5 October, 2013.

17. Secure 1st position in Galaxy Surfactant industry defined problem in Young Innovator Choice Competition (YICC) - 2012 held at Institute of Chemical Technology, Mumbai, India

18. Travel Grant Department of Biotechnology (DBT) Government of India, for presenting paper at 13thInternational Congress of the Society for Ethnopharmacology, Graz, Austria, 2012.

• Date of Birth: 06/30/85
• Gender: Male
• Nationality: Indian
• Marital Status: Married

Junior Research Fellowship by University Grants Commission (UGC)- Government of India for the period of two years during Master’s Degree (2010-2012) at Institute of Chemical Technology, Mumbai, India.

Junior Research Fellowship by University Grants Commission (UGC)- Government of India) for the period of Ph.D. degree (2012-2014) at Institute of Chemical Technology, Mumbai, India.

Senior Research Fellowship by University Grants Commission (UGC)- Government of India) for the period of Ph.D. degree (from 2015 to 2017 ) at Institute of Chemical Technology, Mumbai, India.

Editorial board:

Molecular Neurobiology (Associate Editor), Journal of Alzheimer disease (Associate Editor)

Annals of Neuroscience Scientific Reports (Nature Portfolio Journal)

Reviewer:Neuropsychiatry, Scientific Reports, Oxidative Medicine and Cellular Longevity, Molecular Neurobiology, Molecular Biology, Molecular Neurobiology, Frontier in Neuroscience, Frontiers in Pharmacology, Frontier in Molecular Biosciences, Future Medicinal Chemistry, International Journal of neuroscience. Journal of Biological Sciences, Wyno academic journals.

1. Member of Asia Pacific Society for Neurochemistry (23-0050-R)

2. Member of Japanese Neuroscience Society (JNS): 2212266471

3. Member of The International Society for Neurochemistry (ISN)-(21741)

4. Member of International Parkinson and Movement Disorder Society (MDS)- (39982)

5. Lifetime member of Indian Pharmacological Society (LD-292)

6. Lifetime Member of Indian Academy of Neuroscience (IAN)-(LK-143)

7. Lifetime Member of Society for Neurochemistry, India (SNCI)- (LM-I-662)

8. Life Member of Association of Physiologist & Pharmacologist of India. (3187)

9. Life Member Association of Pharmaceutical Teachers of India (TL/LM-916)