Dr. Pandilla Ramaswamy

Experienced scientist with a strong background in cancer research and biotechnological advancements, skilled in genomic techniques, molecular cloning, and qPCR. Proven ability to design and execute experiments, analyze data, and provide academic support. Seeking to leverage expertise in biochemistry to contribute to innovative research and development in a dynamic environment.

Indian Association for Cancer Research (IACR), Mumbai, 2010

• Identification of molecular aberrations in esophageal squamous cell carcinoma, 12/02/13 - 12/05/13, 82nd Annual Meeting of The Society of Biological Chemists (India) and International Conference on Genome: Mechanism and Function, School of Life Sciences, University of Hyderabad, India
• Analysis of molecular aberrations in squamous cell carcinoma and adenocarcinoma of the esophagus, 08/14/12 - 08/18/12, Mechanism and Model of Cancer Conference, Cold Spring Harbor Laboratory (CSHL), New York, USA
• Identification of molecular aberrations in squamous cell carcinoma and adenocarcinoma of the esophagus in India, 11/19/12 - 11/20/12, 2nd Global Cancer Genomics Consortium TMC symposium, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Kharghar, Navi Mumbai, India
• Molecular and pathological analysis of squamous cell carcinoma and adenocarcinoma of the esophagus, 02/20/10 - 02/23/10, 29th Annual convention of Indian Association of Cancer Research (IACR) and symposium on 'Cancer Stem cell', Amrita Institute of Medical Sciences and Research Centre, Cochin, India
• International Symposium on Frontiers in Genetics and Biotechnology - Retrospect and Prospect, 01/08/06 - 01/10/06, Organized by the Department of Genetics, Osmania University, Hyderabad, India
• Indo-German science and technology symposium, 11/01/04 - 11/02/04, Held at University of Hyderabad, Hyderabad, India

• Awarded a stipend from Cold Spring Harbor Laboratory (CSHL) for attending 'Mechanisms and models of Cancer', 08/14/12 - 08/18/12, Cold Spring Harbor Laboratory (CSHL), New York, USA
• Awarded Indian Council of Medical Research Junior and Senior Research Fellowships for pursuing PhD, 2007, Government of India
• Qualified Graduate Aptitude Test in Engineering (GATE) and secured all India Rank 482, 2007
• Secured 2nd Rank in M.Sc entrance exam conducted by Osmania University, 2003-2004

Micro array based Comparative Genomic Hybridization (aCGH), Gene expression micro array (Agilent 44K human array), Genotyping, Quantitative PCR, RT-PCR, DNA, RNA isolation from various starting material including patient tissue samples, Formalin Fixed paraffin Embedded (FFPE) tissue blocks and blood, Manual micro-dissection for enrichment of tumor cells from FFPE sections, Immunohistochemistry, Genotyping, Plasmid DNA Isolation, Agarose gel electrophoresis, Molecular cloning, PCR, Mutation screening through bidirectional Sanger sequencing, Real-time PCR, Making of Formalin Fixed paraffin Embedded (FFPE) blocks from patient tissue, Collecting and maintain patient data, Handling of various cell lines, Maintenance of epithelial cell cultures, Lymphoblast cultures, Good expertise with MS Office, Adobe Photoshop based applications in biology, Gene Set Enrichment Analysis (GSEA), Significance Analysis of Micro array (SAM), CGH fused lasso, Basics of R programme

• Dr. M D Bashyam, Staff Scientist & Head, Laboratory of Molecular Oncology, Centre for DNA Fingerprinting and Diagnostics, Tuljaiguda complex, Nampally, Hyderabad, Telangana, 500001, India, bashyam@cdfd.org.in
• Dr. Rashna Bhandari, Staff Scientist & Head, Laboratory of Cell signaling, Centre for DNA Fingerprinting and Diagnostics, Tuljaiguda complex, Nampally, Hyderabad, Telangana, 500001, India, rashna@cdfd.org.in
• Dr. Sharat chandra Arandkar, Principal Investigator, ACTREC Tata memorial Centre, Kharghar, Navi mumbai, Maharastra 410210, India, sarandkar@actrec.gov.in

• Sara A George, Viswakalyan Kotapalli, Pandilla Ramaswamy, Raju Kumar, Swarnalata Gowrishankar, Shantveer G Uppin, Murali D Bashyam. Novel oncogenic transcriptional targets of mutant p53 in Esophageal Squamous Cell Carcinoma. J Cell Biochem; 2024.
• TP53 Pro72 Allele Is Enriched in Oral Tongue Cancer and Frequently Mutated in Esophageal Cancer in India, Raju S. R. Adduri, Rajender Katamoni, Ramaswamy Pandilla, Sandeep N. Madana, Arun Kumar Paripati, Viswakalyan Kotapalli, Murali Dharan Bashyam, PLOS ONE, 12/01/14, 9, 12, e114002
• Distinct genetic aberrations in esophageal adeno and squamous carcinoma, Ramaswamy Pandilla, Viswakalyan Kotapalli, Swarnalata Gowrishankar, Mohana Vamsy Chigurupati, Sujith Patnaik, Shantveer Uppin, Subramanyeshwar Rao, Narasimha Raju Kalidindi, Sastry Regulagadda, Challa Sundaram, Mukta Srinivasulu, Anjayneyulu Vasala, Murali Dharan Bashyam, European Journal of Clinical Investigation, 01/01/13, 43, 1233-1239

Identification and analyses of genetic aberrations in Esophageal Cancer.