Summary
Overview
Work History
Education
Skills
Websites
Affiliations
Research Interests
Professional Licenses
Presentations
Additional Training Skills
Research Techniques
Personal Information
Awards
Publications
Languages
Timeline
Generic
KISHORE REDDY MANDAPATI

KISHORE REDDY MANDAPATI

Hyderabad

Summary

A competent and dynamic professional with couple of years of experience wide exposure in the fields of Medicinal chemistry, Organic synthesis, peptide molecules, nucleotides and X-ray crystallographic studies.

Overview

18
18
years of professional experience
1
1
Language

Work History

Lead Investigator

Lillian Laboratories Private Limited
01.2022 - Current
  • Synthesis of Medicinal chemistry, Custom synthesis, Building blocks and peptide compounds with scale up from mg to kg levels
  • Carefully carried out Enzymatic catalytic reactions Optimizing & scaling up of NCEs and their intermediates at large scale with cost reduction, followed by ICH guidelines (cGMP, GLP, GDP & MSDS).

Research Scientist

SNR Pharma & HETERO LABS LIMITED
01.2016 - 01.2020
  • Design & synthesis of biologically active molecules for Medicinal research
  • Synthesis, optimization of robustness process for Oncology & Non-Oncology products of API, Intermediated molecules and their polymorphism studies Literature searches for active pharmaceutical ingredients through chemical abstracts, exposure in patent evaluation and by using effective resources (IPM rights-internet resources).

Senior Research Chemist

GLOCHEM Industries Ltd.
01.2006 - 01.2008
  • Carried out the projects involved in the synthesis and characterization of the pharmaceutical API’s & their Intermediates.

Education

Postdoctoral Researcher - Chemistry

Taros Chemicals GmbH & Co. KG
12.2022

Ph.D - Chemistry

State University of Campinas (UNICAMP)
12.2016

Master's Degree - Organic Chemistry

Acharya Nagarjuna University
12.2006

Bachelor's Degree - Chemistry, Physics & Mathematics

Kakatiya University
12.2003

Skills

  • SciFinder
  • Reaxys
  • MestReNova
  • TopSpin
  • PubMed
  • Scopus & chemical abstracts
  • ChemDraw
  • Marvin Sketch
  • Origin

Affiliations

  • Indian Crystallographic Association
  • Lead Six Sigma learning Association at VALUE enablers Pvt. Ltd.

Research Interests

  • Synthetic Organic Chemistry
  • Medicinal Chemistry

Professional Licenses

  • Post Graduate Diploma in Regulatory Affairs (PGDRA), Global Institute of Regulatory Affairs (GIRA), India, 2021-01-01, 2023-12-31
  • Global Regulatory Affairs in Pharmaceutical Industry: Due Diligence on Current Trends & Practices, KBIPER, India, 2023
  • Project Management course, India, 2023-01-01, 2023-12-31
  • Good Manufacturing Certificate (GMP), RAAJ GPRAC PVT. LTD., India, 2021
  • Organic Chemistry, India, 2020

Presentations

12, 7, 5, True, True

Additional Training Skills

  • Design, Development and scale-up of safe chemical processes and operations
  • High-Impact Writing in Science
  • Beyond the Rule of Five
  • Virtual Screening: How to do it better and how to know you are doing better
  • Safety and Waste Treatment in the Chemical Laboratory
  • Symmetry and Structure in Solid state
  • Single crystal & Powder X-ray Diffraction

Research Techniques

  • Powder XRD
  • Single molecule X-ray crystallography
  • NMR
  • MASS
  • ORD
  • UV-Vis
  • IR
  • DSC
  • HPLC
  • LC-MS
  • GC-MS
  • Mass spectrometry
  • Pymol
  • VIDA
  • CCP4

Personal Information

Nationality: Indian

Awards

  • Postdoctoral fellowship, Taros Chemicals GmbH & Co. KG, Germany, 2021
  • Current Drug Discovery for Neglected Diseases fellowship, Brazil, 2015
  • São Paulo School of Advanced Science (ESPCA) fellowship, Brazil, 2013
  • FAPESP Grant Number: 2009/51602-5 & 13/16174-8, Brazil, 2009
  • TWAS/CNPq PG-Fellowship (CNPq PG FT 2011/Mandapati–190655/2011–9), Brazil, 2012
  • TWAS travel fellowship (CNPq PG FT 2011/Mandapati–190655/2011–9), Italy, 2012
  • Research assistant Fellowship (CP 6382/0205/10-555 & SID-23014), IISc, India, 2009

Publications

  • Observation of 3D isostructurality in halogen substituted N-benzoyl-N-phenylbenzamides, J. Mol. Struct., 2018, 1164, 280-288, Rahul Shukla, Susanta K. Nayak, Deepak Chopra, M. Kishore Reddy, T. N. Guru Row
  • Quantitative Investigation of intermolecular interactions in dimorphs of 3-Chloro-N-(2- fluorophenyl) benzamide and 2-Iodo-N-(4- bromophenyl) benzamide, J. Chem. Sci., 2018, 130, 38, Rahul Shukla, Susanta K. Nayak, Deepak Chopra, M. Kishore Reddy, Tayur N. Guru Row
  • Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates, Bioorg. Med. Chem., 2015, 23, 4462-4471, Emanuella M. B. Fonseca, Daniela B. B. Trivella, Valéria Scorsato, Mariana P. Dias, Natália L. Bazzo, Kishore R. Mandapati, Fábio L. de Oliveira, Carmen V. Ferreira-Halder, Ronaldo A. Pilli, Paulo C. M. L. Miranda, Ricardo Aparicio
  • Evaluation of the role of disordered organic fluorine in crystal packing: insights from halogen substituted benzanilides, CrystEngComm, 2012, 14, 200-210, Susanta K. Nayak, M. Kishore Reddy, Deepak Chopra, Tayur N. Guru Row
  • Role of Hetero-Halogen (F
  • X, X = Cl, Br and I) or Homo-Halogen (X∙∙∙X, X = F, Cl, Br and I) Interactions in Substituted Benzanilides, Cryst. Growth Des., 2011, 11, 1578-1596, Susanta K. Nayak, M. Kishore Reddy, Tayur N. Guru Row, Deepak Chopra
  • Supramolecular assembly of hetero- halogen (F∙∙∙X) or HomoHalogen (X∙∙∙X, X = F, Cl, Br, and I) interactions in substituted benzanilides, Acta. Cryst., 2011, A67, C601, Susanta K. Nayak, M. Kishore Reddy, T. N. Guru Row
  • 4-Chloro-N-(3-chlorophenyl) benzamide, Acta Cryst., 2009, E65, o2434, Susanta K. Nayak, M. Kishore Reddy, Tayur N. Guru Row

Languages

English
Advanced (C1)
Portuguese
Upper intermediate (B2)
Telugu
Bilingual or Proficient (C2)
Hindi
Upper intermediate (B2)

Timeline

Lead Investigator

Lillian Laboratories Private Limited
01.2022 - Current

Research Scientist

SNR Pharma & HETERO LABS LIMITED
01.2016 - 01.2020

Senior Research Chemist

GLOCHEM Industries Ltd.
01.2006 - 01.2008

Postdoctoral Researcher - Chemistry

Taros Chemicals GmbH & Co. KG

Ph.D - Chemistry

State University of Campinas (UNICAMP)

Master's Degree - Organic Chemistry

Acharya Nagarjuna University

Bachelor's Degree - Chemistry, Physics & Mathematics

Kakatiya University
KISHORE REDDY MANDAPATI