A competent and dynamic professional with couple of years of experience wide exposure in the fields of Medicinal chemistry, Organic synthesis, peptide molecules, nucleotides and X-ray crystallographic studies.
Overview
18
18
years of professional experience
1
1
Language
Work History
Lead Investigator
Lillian Laboratories Private Limited
01.2022 - Current
Synthesis of Medicinal chemistry, Custom synthesis, Building blocks and peptide compounds with scale up from mg to kg levels
Carefully carried out Enzymatic catalytic reactions Optimizing & scaling up of NCEs and their intermediates at large scale with cost reduction, followed by ICH guidelines (cGMP, GLP, GDP & MSDS).
Research Scientist
SNR Pharma & HETERO LABS LIMITED
01.2016 - 01.2020
Design & synthesis of biologically active molecules for Medicinal research
Synthesis, optimization of robustness process for Oncology & Non-Oncology products of API, Intermediated molecules and their polymorphism studies Literature searches for active pharmaceutical ingredients through chemical abstracts, exposure in patent evaluation and by using effective resources (IPM rights-internet resources).
Senior Research Chemist
GLOCHEM Industries Ltd.
01.2006 - 01.2008
Carried out the projects involved in the synthesis and characterization of the pharmaceutical API’s & their Intermediates.
Current Drug Discovery for Neglected Diseases fellowship, Brazil, 2015
São Paulo School of Advanced Science (ESPCA) fellowship, Brazil, 2013
FAPESP Grant Number: 2009/51602-5 & 13/16174-8, Brazil, 2009
TWAS/CNPq PG-Fellowship (CNPq PG FT 2011/Mandapati–190655/2011–9), Brazil, 2012
TWAS travel fellowship (CNPq PG FT 2011/Mandapati–190655/2011–9), Italy, 2012
Research assistant Fellowship (CP 6382/0205/10-555 & SID-23014), IISc, India, 2009
Publications
Observation of 3D isostructurality in halogen substituted N-benzoyl-N-phenylbenzamides, J. Mol. Struct., 2018, 1164, 280-288, Rahul Shukla, Susanta K. Nayak, Deepak Chopra, M. Kishore Reddy, T. N. Guru Row
Quantitative Investigation of intermolecular interactions in dimorphs of 3-Chloro-N-(2- fluorophenyl) benzamide and 2-Iodo-N-(4- bromophenyl) benzamide, J. Chem. Sci., 2018, 130, 38, Rahul Shukla, Susanta K. Nayak, Deepak Chopra, M. Kishore Reddy, Tayur N. Guru Row
Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates, Bioorg. Med. Chem., 2015, 23, 4462-4471, Emanuella M. B. Fonseca, Daniela B. B. Trivella, Valéria Scorsato, Mariana P. Dias, Natália L. Bazzo, Kishore R. Mandapati, Fábio L. de Oliveira, Carmen V. Ferreira-Halder, Ronaldo A. Pilli, Paulo C. M. L. Miranda, Ricardo Aparicio
Evaluation of the role of disordered organic fluorine in crystal packing: insights from halogen substituted benzanilides, CrystEngComm, 2012, 14, 200-210, Susanta K. Nayak, M. Kishore Reddy, Deepak Chopra, Tayur N. Guru Row
Role of Hetero-Halogen (F
X, X = Cl, Br and I) or Homo-Halogen (X∙∙∙X, X = F, Cl, Br and I) Interactions in Substituted Benzanilides, Cryst. Growth Des., 2011, 11, 1578-1596, Susanta K. Nayak, M. Kishore Reddy, Tayur N. Guru Row, Deepak Chopra
Supramolecular assembly of hetero- halogen (F∙∙∙X) or HomoHalogen (X∙∙∙X, X = F, Cl, Br, and I) interactions in substituted benzanilides, Acta. Cryst., 2011, A67, C601, Susanta K. Nayak, M. Kishore Reddy, T. N. Guru Row
4-Chloro-N-(3-chlorophenyl) benzamide, Acta Cryst., 2009, E65, o2434, Susanta K. Nayak, M. Kishore Reddy, Tayur N. Guru Row
Senior Clinical Project Coordinator at Labcorp Laboratories India Private LimitedSenior Clinical Project Coordinator at Labcorp Laboratories India Private Limited