A competent and dynamic professional with couple of years of experience wide exposure in the fields of Medicinal chemistry, Organic synthesis, peptide molecules, nucleotides and X-ray crystallographic studies.
Overview
18
18
years of professional experience
1
1
Language
Work History
Lead Investigator
Lillian Laboratories Private Limited
01.2022 - Current
Synthesis of Medicinal chemistry, Custom synthesis, Building blocks and peptide compounds with scale up from mg to kg levels
Carefully carried out Enzymatic catalytic reactions Optimizing & scaling up of NCEs and their intermediates at large scale with cost reduction, followed by ICH guidelines (cGMP, GLP, GDP & MSDS).
Research Scientist
SNR Pharma & HETERO LABS LIMITED
01.2016 - 01.2020
Design & synthesis of biologically active molecules for Medicinal research
Synthesis, optimization of robustness process for Oncology & Non-Oncology products of API, Intermediated molecules and their polymorphism studies Literature searches for active pharmaceutical ingredients through chemical abstracts, exposure in patent evaluation and by using effective resources (IPM rights-internet resources).
Senior Research Chemist
GLOCHEM Industries Ltd.
01.2006 - 01.2008
Carried out the projects involved in the synthesis and characterization of the pharmaceutical API’s & their Intermediates.
Current Drug Discovery for Neglected Diseases fellowship, Brazil, 2015
São Paulo School of Advanced Science (ESPCA) fellowship, Brazil, 2013
FAPESP Grant Number: 2009/51602-5 & 13/16174-8, Brazil, 2009
TWAS/CNPq PG-Fellowship (CNPq PG FT 2011/Mandapati–190655/2011–9), Brazil, 2012
TWAS travel fellowship (CNPq PG FT 2011/Mandapati–190655/2011–9), Italy, 2012
Research assistant Fellowship (CP 6382/0205/10-555 & SID-23014), IISc, India, 2009
Publications
Observation of 3D isostructurality in halogen substituted N-benzoyl-N-phenylbenzamides, J. Mol. Struct., 2018, 1164, 280-288, Rahul Shukla, Susanta K. Nayak, Deepak Chopra, M. Kishore Reddy, T. N. Guru Row
Quantitative Investigation of intermolecular interactions in dimorphs of 3-Chloro-N-(2- fluorophenyl) benzamide and 2-Iodo-N-(4- bromophenyl) benzamide, J. Chem. Sci., 2018, 130, 38, Rahul Shukla, Susanta K. Nayak, Deepak Chopra, M. Kishore Reddy, Tayur N. Guru Row
Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates, Bioorg. Med. Chem., 2015, 23, 4462-4471, Emanuella M. B. Fonseca, Daniela B. B. Trivella, Valéria Scorsato, Mariana P. Dias, Natália L. Bazzo, Kishore R. Mandapati, Fábio L. de Oliveira, Carmen V. Ferreira-Halder, Ronaldo A. Pilli, Paulo C. M. L. Miranda, Ricardo Aparicio
Evaluation of the role of disordered organic fluorine in crystal packing: insights from halogen substituted benzanilides, CrystEngComm, 2012, 14, 200-210, Susanta K. Nayak, M. Kishore Reddy, Deepak Chopra, Tayur N. Guru Row
Role of Hetero-Halogen (F
X, X = Cl, Br and I) or Homo-Halogen (X∙∙∙X, X = F, Cl, Br and I) Interactions in Substituted Benzanilides, Cryst. Growth Des., 2011, 11, 1578-1596, Susanta K. Nayak, M. Kishore Reddy, Tayur N. Guru Row, Deepak Chopra
Supramolecular assembly of hetero- halogen (F∙∙∙X) or HomoHalogen (X∙∙∙X, X = F, Cl, Br, and I) interactions in substituted benzanilides, Acta. Cryst., 2011, A67, C601, Susanta K. Nayak, M. Kishore Reddy, T. N. Guru Row
4-Chloro-N-(3-chlorophenyl) benzamide, Acta Cryst., 2009, E65, o2434, Susanta K. Nayak, M. Kishore Reddy, Tayur N. Guru Row