Venkateshwarlu Gurram

Synthetic chemist with over 19 years’ experience an excellent background in synthesis of mg to multi gram scales, especially impurity synthesis, Nitrosamines, heterocyclic chemistry, library synthesis, Pd catalyzed and nucleosides. Significant experience of managing team with multiple projects in parallel from planning, problem solving the synthetic routes and supervising synthetic work and ensure all the projects are completed on timely manner to the customer. Creative and innovative in solving in organic synthesis. Developed good leadership skills and excellent team player ability from working in collaborative and multicultural environment.

• Managing team (10 member’s) to meet productivity as per client requirement.
• Synthetic route design, providing scientific guidance to team member and troubleshoot scientific challenges for delivery of targets.
• Preparing weekly updates and final report, e-mail responses and participating in teleconference with the clients.
• Responsible for project timelines and deliverables.
• Proactively evaluate and incorporate new techniques and technology into research activity as needed.
• Preparation of quotations and proposals. Cost reduction using alternative scheme and raw material.
• Review the e-note book, reagent tracking, shipment tracking and other miscellaneous document.
• Coordinating with cross functional team (CFT) like SCM, stores, logistics, Analytical maintenance and etc.
• Recognize the best performance through various rewards and recognition.
• Responsible for lab safety, Implementing safety protocol in the lab.

• C-C Cross-Coupling Reactions of O6-Alkyl-2-Haloinosine Derivatives and a One-Pot Cross-Coupling/O6-Deprotection Procedure., Venkateshwarlu Gurram, Narender Pottabathini, Ramesh Garlapati, Avinash B. Chaudhary, Balaram Patro, Mahesh K. Lakshman., Chem. Asian J., 2012, 7, 1853–1861
• Design, synthesis, and biological evaluation of quinazoline derivatives as α-glucosidase inhibitors., Venkateshwarlu Gurram, Ramesh Garlapati, Chiranjeevi Thulluri, Nagaraju Madala, Kumara Swamy Kasani, Pavan Kumar Machiraju, Raju Doddapalla, Uma Addepally, Rambabu Gundla, Balaram Patro, Narender Pottabathini., Med Chem Res., 2015, 24, 2227-2237
• Mild and General Access to Diverse 1H-Benzotriazoles via Diboron-Mediated N–OH Deoxygenation, and Palladium-Catalyzed C–C and C–N Bond Formation., Venkateshwarlu Gurram, Hari K Akula, Ramesh Garlapati, Narender Pottabathini, Mahesh K. Lakshman., Adv. Synth. Catal., 2015, 357, 451-462
• Concise Total Synthesis of (−)-Erinapyrone B from D-(+)-Malic Acid., Ramakrishna Samala, Venkateshwarlu Gurram, Balaram Patro, Narender Pottabathini, and K. Mukkanti., Synth. Commun., 2014, 44, 500-506
• Development of α-glucosidase inhibitors by room temperature C–C cross couplings of quinazolinones., Ramesh Garlapati, Narender Pottabathini, Venkateshwarlu Gurram, Kumara Swamy Kasani, Rambabu Gundla, Chiranjeevi Thulluri, Pavan Kumar Machiraju, Avinash B. Chaudhary, Uma Addepally, Raveendra Dayam, Venkata Rao Chunduri and Balaram Patro., Org. Biomol. Chem., 2013, 11, 4778-4791
• Pd-catalyzed amination of 6-halo-2-cyclopropyl-3-(pyridyl-3-ylmethyl) quinazolin-4(3H)one., Ramesh Garlapati, Narender Pottabathini, Venkateshwarlu Gurram, Avinash B. Chaudhary, Venkata Rao Chunduri, Balaram Patro., Tetrahedron Letters, 2012, 53, 5162-5166
• Cladribine Analogues via O6-(Benzotriazolyl) Derivatives of Guanine Nucleosides., Satish Sakilam, Vuram Prasanna Kumar, Siva Subrahmanyam Relangi, Venkateshwarlu Gurram, Hong Zhou, Robert J. Kreitman, Michelle M. Martínez Montemayor, Lijia Yang, Narender Pottabathini, Mahesh K. Lakshman., Molecules, 2015, 20, 18437−18463
• Pd catalyzed C–N Bond Forming Reactions of 6- Bromo-2-cyclopropyl-3-(pyridyl-3-ylmethyl)-4-quinazolin-(3H)-one at Room Temperature., Narender Pottabathini, Ramesh Garlapati, Venkateshwarlu Gurram, Suresh Poudapally, Pavan K. Machiraju and Somesh Sharma., Current Organocatalysis, 2016, 3, 292-300
• Cu-free Sonogashira type cross-coupling of 6-halo-2-cyclopropyl-3-(pyridyl-3-ylmethyl) quinazolin-4(3H)-ones as potential antimicrobial agents., Suresh Poudapally, Venkateshwarlu Gurram, Ramesh Garlapati, Chiranjeevi Thulluri, Uma Addepally, Vidya K, Somesh Sharma, Subhabrata Sen, Narender Pottabathini., J. Heterocycl. Chem., 2017, 54, 2272-2286
• Suzuki–Miyaura coupling of quinazolines containing an unprotected NH2 group: Synthesis and biological testing of quinazoline derivatives., Yadagiri Pulipati, Venkateshwarlu Gurram, S. Vijaya Laxmi, Yennam Satyanarayana, Karan Singh, Vinod Kumar, Somesh Sharma, Narender Pottabathini, Vijaya Bhaskara Reddy Iska., Synth. Commun., 2017, 47, 1142-1150
• Pd-Catalyzed versus Uncatalyzed, PhI(OAc)2-Mediated Cyclization Reactions of N6-([1,1′-Biaryl]-2-yl)Adenine Nucleosides., Sakilam Satishkumar, Suresh Poudapally, Prasanna K. Vuram, Venkateshwarlu Gurram, Narender Pottabathini, Dellamol Sebastian, Lijia Yang, Padmanava Pradhan, Mahesh K. Lakshman., Chem Cat Chem., 2017, 9, 4058-4069
• The Disappearing Director: The Case of Directed N-Arylation via a Removable Hydroxyl Group., Magdalena R. Andrzejewska, Prasanna K. Vuram, Narender Pottabathini, Venkateshwarlu Gurram, Siva Subrahmanyam Relangi, Kirill A. Korvinson, Raju Doddipalla, Lothar Stahl, Michelle C. Neary, Padmanava Pradhan, Somesh Sharma, Mahesh K. Lakshman., Adv. Synth. Catal., 2018, 360, 2503-2510