Summary
Overview
Work History
Education
Skills
Accomplishments
Additional Information
Timeline
Generic

Vimalathithan Devaraj

Computational Biologist
Bengaluru

Summary

Computational biologist with 9+ years of experience in conducting research to study human diseases and drive healthcare improvements. Investigative professional leading translational research to support drug discovery. Critical thinker with background developing and improving methodologies and algorithms for data analysis and infer insights to the original problem statement.

Overview

11
11
years of professional experience
10
10
years of post-secondary education

Work History

Senior Research Investigator

Syngene International Limited
05.2022 - Current

I lead a team of computational biologists majorly working on various stages of drug discovery with more emphasize on reducing the turn around time.

  • Developed a computational Target Identification workflow to prioritize targets given a disease condition through high-throughput -omics data analysis followed by network analysis.
  • Build an insilico perturbation model to study the Target-Disease causation of the prioritized targets
  • Streamlined the Target Assessment workflows

Lead a complete informatics support project for a client to analyze GCMS/LCMS data

  • Created a python-based workflow to extract spectra data from raw files and create a spectra library
  • Built a deep learning model to predict the mass spectra of a compound using graph embedding of the compound structure.

Proposed and formulated methods to translate and infer insights on species with sparse data from a well studied organism

Principal Scientist

Perfect Day India Private Limited
10.2020 - 03.2022

Worked at the interface of several scientific groups including the upstream and the downstream processing of fermentation.
• Involved in building predictive models from experimental data and developing solutions depending on the project need.
• Building gene regulatory networks from experimental data to understand the signal processing machinery of the host organism.
• Transcriptome and proteome data analysis to understand the physiological changes in cells during the fermentation process.
• Multivariate data analysis to understand the efficiency of fermentation processes.
• Generate hypotheses from the observations/ scientific literature and design experiments to validate the idea.

Assistant System Engineer Trainee

Tata Consultancy Services
07.2013 - 06.2014
  • Worked in a data warehouse project as a Business Intelligence Developer.
  • ETL data processing using Informatica, BusinessObjects.

Education

Ph.D. - Systems Biology

Indian Institute of Technology Guwahati
India
07.2014 - 07.2020

B.Tech. - Industrial Biotechnology

SASTRA University
India
07.2009 - 05.2013

Skills

    Team Management

Mathematical modeling of biological systems

Analysis of high-throughput biological data

Data driven predictive model building and analysis

Accomplishments

    Devaraj V., Bose B. DEBay: a computational tool for deconvolution of quantitative PCR data for estimation of cell type-specific gene expression in a mixed population.
    Heliyon. July 2020.
    https://doi.org/10.1016/j.heliyon.2020.e04489


    Devaraj V., Bose B. The Mathematics of Phenotypic State Transition: Paths and Potential.
    Journal of the Indian Institute of Science. May 2020.
    https://doi.org/10.1007/s41745-020-00173-6


    Devaraj V., Bose B. Morphological State Transition Dynamics in EGF-induced Epithelial to Mesenchymal Transition.
    Journal of Clinical Medicine. June 2019.
    DOI: 10.3390/jcm8070911


    Dutta P., Devaraj V., Bose B. A Negative Feedback Regulates The Flow of Signal Through Akt/mTORC1/S6K1 Pathway.
    Preprint. September 2017.
    https://doi.org/10.1101/147710

Additional Information

Teaching Assistant
Introduction to Dynamics Models in Biology
Massive Open Online Course (MOOC)

Timeline

Senior Research Investigator

Syngene International Limited
05.2022 - Current

Principal Scientist

Perfect Day India Private Limited
10.2020 - 03.2022

Ph.D. - Systems Biology

Indian Institute of Technology Guwahati
07.2014 - 07.2020

Assistant System Engineer Trainee

Tata Consultancy Services
07.2013 - 06.2014

B.Tech. - Industrial Biotechnology

SASTRA University
07.2009 - 05.2013
Vimalathithan DevarajComputational Biologist