
Computational biologist with 9+ years of experience in conducting research to study human diseases and drive healthcare improvements. Investigative professional leading translational research to support drug discovery. Critical thinker with background developing and improving methodologies and algorithms for data analysis and infer insights to the original problem statement.
I lead a team of computational biologists majorly working on various stages of drug discovery with more emphasize on reducing the turn around time.
Lead a complete informatics support project for a client to analyze GCMS/LCMS data
Proposed and formulated methods to translate and infer insights on species with sparse data from a well studied organism
Worked at the interface of several scientific groups including the upstream and the downstream processing of fermentation.
• Involved in building predictive models from experimental data and developing solutions depending on the project need.
• Building gene regulatory networks from experimental data to understand the signal processing machinery of the host organism.
• Transcriptome and proteome data analysis to understand the physiological changes in cells during the fermentation process.
• Multivariate data analysis to understand the efficiency of fermentation processes.
• Generate hypotheses from the observations/ scientific literature and design experiments to validate the idea.
Team Management
Mathematical modeling of biological systems
Analysis of high-throughput biological data
Data driven predictive model building and analysis
Devaraj V., Bose B. DEBay: a computational tool for deconvolution of quantitative PCR data for estimation of cell type-specific gene expression in a mixed population.
Heliyon. July 2020.
https://doi.org/10.1016/j.heliyon.2020.e04489
Devaraj V., Bose B. The Mathematics of Phenotypic State Transition: Paths and Potential.
Journal of the Indian Institute of Science. May 2020.
https://doi.org/10.1007/s41745-020-00173-6
Devaraj V., Bose B. Morphological State Transition Dynamics in EGF-induced Epithelial to Mesenchymal Transition.
Journal of Clinical Medicine. June 2019.
DOI: 10.3390/jcm8070911
Dutta P., Devaraj V., Bose B. A Negative Feedback Regulates The Flow of Signal Through Akt/mTORC1/S6K1 Pathway.
Preprint. September 2017.
https://doi.org/10.1101/147710
Teaching Assistant
Introduction to Dynamics Models in Biology
Massive Open Online Course (MOOC)