Summary
Overview
Work History
Education
Skills
Workshops Training
Publications
Projects
Training
Timeline
Generic

Manasi Patil

PhD Scholar
Bangalore

Summary

Proficient researcher in stem cell biology with a substantial background in mammalian stem cell culture and a strong molecular biology skill set. Proven capacity to work independently and collaborate with the team to meet project terms.

Overview

7
7
years of professional experience
5
5
years of post-secondary education
4
4
Languages

Work History

PhD Scholar

Manipal Institute of Regenerative Medicine
04.2017 - 03.2024

Modelling Alzheimer’s Disease Using Mesenchymal Stem Cells And Investigation Of Wnt Antagonism During Neurodegeneration Process.(Thesis submitted March- 2024)

Project fellow

Manipal Institute of Regenerative Medicine
  • Isolation and maintenance of human Mesenchymal Stem cells
  • Handling glioblastoma and breast cancer cell lines
  • Gene overexpression and silencing studies
  • Immunocytochemistry

Project Intern

Manipal Institute of Regenerative Medicine
  • Maintenance of mammalian cell cultures, breast cancer and glioblastoma lines
  • Immunocytochemistry

Education

Master of Science - MSc Biotechnology

Fergusson College
07.2012 - 05.2014

Bachelor of Science - BSc Biotechnology

Fergusson College
07.2009 - 05.2012

Postgraduate Diploma in Cellular and Molecular Diagnostics - Biotechnology Finishing School: Initiative Launche

Oxford College of Science And Technology
Bengaluru, India
10.2015 - 05.2016

PhD Scholar - Modelling Alzheimer's Disease Using Human Mesenchymal Stem Cells

Manipal Institute of Regenerative Medicine

Skills

Cell culture techniques-cancer cell lines, primary cultures- fibroblasts and stem cellsundefined

Workshops Training

  • 7-day industrial training (Packaging of vaccine, production of DPT vaccine, etc.), Serum Institute Pvt. Ltd., Pune, India, 05/2011
  • Attended 5-day workshop at the Institute Of Excellence, Mysore on handling of sophisticated instruments (LC-MS, NMR, XRD, SEM), 03/2016

Publications

  • Research article, Manasi Patil, Naisarg Gamit, Arun Dharmarajan, Gautam Sethi 5, and Sudha Warrier, 02/02/2023, Bioengineering, MDPI, Identification of a Novel Wnt Antagonist Based Therapeutic and Diagnostic Target for Alzheimer’s Disease Using a Stem Cell-Derived Model
  • Research article, Naisarg Gamit, Manasi Patil, Soumya B Sundrappa, S. Mohana Sundaram, Gautam Sethi, Arun Dharmarajan, Sudha Warrier, 08/11/2023, Drug Development Research, Mesenchymal stem cell-derived rapid drug screening system for Alzheimer's disease for the identification of novel drugs
  • Review, Sudha Warrier, Manasi Patil , Sanyukta Bhansali , Lavanya Varier, Gautam Sethi, 01/2021, Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, Designing precision medicine panels for drug-refractory cancers targeting cancer stemness traits
  • Research article, Gurubharathi Bhuvanalakshmi, Naisarg Gamit, Manasi Patil, Frank Arfuso, Gautam Sethi, Arun Dharmarajan, Alan Prem Kumar, and Sudha Warrier, 12/2018, Cancers (Basel), Stemness, Pluripotentiality, and Wnt Antagonism: sFRP4, a Wnt antagonist Mediates Pluripotency and Stemness in Glioblastoma

Projects

Alginate production by Azotobacter sp., 01/2014 - 05/2014, MSc. Part 2 project Study on an alternative for Fetal Bovine Serum used in animal tissue culture medium, 08/2011 - 03/2012, BSc final year project

Training

  • Presented a poster and oral presentation on ‘Human Mesenchymal stem cell derived model of Alzheimer's Disease – Effect of Wnt antagonism in neurodegeneration’, 3rd International Conference on INNOVATIONS IN CANCER RESEARCH AND REGENERATIVE MEDICINE (CRRM 2017), Ho Chi Minh city, Vietnam
  • Presented on 'Understanding Covid-19 associated neurological effects and increased risk of Alzheimer’s Disease', Interdisciplinary Conference on Healthcare and Technical Research (ICHTR 2021)
  • Modulating Wnt signaling pathway to combat Alzheimer’s disease pathogenesis, Interdisciplinary Conference on Healthcare and Technical Research (ICHTR 2022)

Timeline

PhD Scholar

Manipal Institute of Regenerative Medicine
04.2017 - 03.2024

Postgraduate Diploma in Cellular and Molecular Diagnostics - Biotechnology Finishing School: Initiative Launche

Oxford College of Science And Technology
10.2015 - 05.2016

Master of Science - MSc Biotechnology

Fergusson College
07.2012 - 05.2014

Bachelor of Science - BSc Biotechnology

Fergusson College
07.2009 - 05.2012

Project fellow

Manipal Institute of Regenerative Medicine

Project Intern

Manipal Institute of Regenerative Medicine

PhD Scholar - Modelling Alzheimer's Disease Using Human Mesenchymal Stem Cells

Manipal Institute of Regenerative Medicine
Manasi PatilPhD Scholar