Neeru Singh

Assistant Professor with 5 years of experience successfully contributing to curriculum development and delivery. Driven to contribute to program outcomes by facilitating engagement and supporting learning objectives. A researcher working in the area of DNA damage repair and implications on cancer therapy, leading 3 grants aligned to the subject

Assistant Professor, Institute of Advanced Research, 03/02/20, Present, Dept. of Biotechnology and Bioengineering

• American Association for Cancer Research, 21/10/16
• American Society of Biochemists and Molecular Biology, 01/01/24

• Selected to present a talk at an international conference of American Society of Biochemists and Molecular Biology, Chicago, Illinois, 04/01/25
• Selected to participate and present work at YIM2025, Agra Courtyard Marriott, 03/01/25
• Invited for a talk at 'Women in Science' lecture series, IIT Gandhinagar, 2024
• Invited talk at an international conference, Puducherry University, 2024
• Invited for a talk at Pan-Biotech conference meet, IIT Chennai, 2019
• Invited for presentation at 78th Annual meeting of American Association for Cancer Research, Chicago, USA, 2018

• Hands-on training workshop on cell culture technique and apoptosis detection assay, 2022, GSBTM, DST
• Hands-on training workshop on fluorescence techniques in cell biology

PhD student: 4 (1 completed)

Dissertation: 9

Project Staff: 2 (JRF)

• Lady Tata memorial trust (2025-2028). Title of grant: To investigate the mechanistic link between ATM pathway and autophagy in TNBC and its therapeutic implications (PI)
• GSBTM (2022-2025). Title of grant: Design and Validation of miR200c AgomiR in combination with AZD2281 as an effective therapeutic strategy against drug resistant Ovarian carcinomas (PI)
• ICMR (2022-2025) .Characterization of role of Mediator of DNA damage checkpoint 1 protein in drug resistance to oncogenic KRAS inhibition in NSCLC and its therapeutic relevance (PI)
• IAR Seed Grant (2020-2021). Novel role of MDC1 in autophagy and its implications in cancer therapy (PI)
• DST women Scientist Sheme A fellowship to support Post-doctoral project (PI)
• CSIR Junior & Senior Research Fellowship (2007-2012) during PhD
• Shyama Prasad Mukherjee fellowship (Qualified for fellowship instituted for top 20% CSIR fellowship awardees), 2006

• Kavya Pandya 1 , Deep Jagani 1 , Charmi Panchal 1 and Neeru Singh 1 * MDC1 Downregulation Enhances the Efficacy of CHK1 Inhibitor AZD7762 in Cervical Cancer Cells. (under Review in J. of Biochemie).
• · Aastha Jadhav, Arjun Menon, Kush Gupta and Neeru Singh (2025). Molecular and therapeutic insight into ER Stress signaling in NSCLC. Journal of Drug targeting. (Accepted) (I.F: 4.5)
• Akhilesh, Arjun Menon, Somesh Agrawal, Deepak Chouhan, Anagha Gadepalli, Bhanuranjan Das, Rajnish Kumar, Neeru Singh & Vinod Tiwari (29 Jan 2024): Virtual screening and molecular dynamics investigations using natural compounds against autotaxin for the treatment of chronic pain, Journal of Biomolecular Structure and Dynamics, DOI: 10.1080/07391102.2024.2308761.(I.F: 5.235)
• Pandya K, Jagani D, Singh N. CRISPR-Cas Systems: Programmable Nuclease Revolutionizing the Molecular Diagnosis. Mol Biotechnol. Published online July 19, 2023. doi:10.1007/s12033-023-00819-7. (I.F: 2.7)
• Pandya, K., & Singh, N. (2022). In silico study reveals unconventional interactions between MDC1 of DDR and Beclin-1 of autophagy. Molecular diversity, 10.1007/s11030-022-10579-2. Advance online publication. https://doi.org/10.1007/s11030-022-10579-2. (I.F:3.46)
• Singh N, Bhakuni R, Chhabria D, Kirubakaran S. MDC1 depletion promotes cisplatin induced cell death in cervical cancer cells. BMC Res Notes. 2020 Mar 11; 13(1):146. doi: 10.1186/s13104-020-04996-5. PMID: 32160908; PMCID: PMC7066845.
• Neeru Singh and M V Rajam (2020). Silencing of the Ornithine Decarboxylase Gene of Fusarium oxysporum f. sp. lycopersici by Host-Induced RNAi Confers Resistance to Fusarium Wilt disease. Plant Mol Bio Rep. Pub Date : 2020-03-03, DOI: 10.1007/s11105-020-01205-2
• Neeru Singh, Rashmi Bhakuni, Sivapriya Kirubakaran (2017). “Validation of NFBD1 as a novel molecular target in cervical cancer therapy utilizing advanced molecular approaches” Canadian Journal of Biotechnology 1:178. 2560-8304.
• Neeru Singh, Rashmi Bhakuni and Sivapriya Kirubakaran (2018). “High MDC1 expression in cervical cancer cells can affect the chemo and radio- therapeutic response as its inhibition leads to increased cell death” Cancer Res (78) 772; DOI: 10.1158/1538-7445.AM2018-772.
• Neeru Singh and Rajam, MV. 2011. “RNA interference and functional genomics in fungi “In: Microorganisms in sustainable Agriculture and Biotechnology (Eds. Satyanarayana T, Johri BN & Anil Prakash), Springer ISBN: 978-94-007-2213-2, 773-789.
• Rajam, MV and Neeru singh. 2010. “Engineering fungal resistance: promises of RNAi”. Proceedings of National symposia on “Molecular approaches for management of fungal diseases of crop plants, Indian Institute of Horticulture research, Bangalore.
• Singh N, Rajam MV (2013). “A Simple and Rapid Glass Bead Transformation Method for a Filamentous Fungus Fusarium oxysporum” Cell Dev Biol., Cell Dev Biol 2:115. doi:10.4172/2168-9296.1000115.

• EMBO Laboratory Leadership Course, IISER Pune, 2024
• Confocal Imaging Workshop, 2009, University of Delhi South Campus, N. Delhi
• DST Women Scientist Workshop, 2018, Mysore University, Biotechnology Department
• CeNSE DBT Nano-biotechnology Alliance (C-DNA) Familiarization Workshop, 05/23/22 to 05/25/22, Centre for Nano Science and Engineering, Indian Institute of Science, Bangalore
• CeNSE DBT Nano-biotechnology Alliance (C-DNA) Hands-on Training Workshop, 06/27/22 to 07/01/22, Centre for Nano Science and Engineering, Indian Institute of Science, Bangalore

• Institute of Advanced Research, Gandhinagar, Gujarat, India, Assistant Professor, DNA damage repair mechanism, cancer biology and therapy, 3
• Indian Institute of Technology Gandhinagar, Gandhinagar, Gujarat, India, DST Women Scientist, Prof. Sivapriya Kirubkaran, Characterization of NFBD1 protein, a mediator of ATM DNA damage response and to explore its potential as a cancer therapeutic target.
• University of Delhi South Campus, New Delhi, India, Junior Research Fellow, Prof. Manchikatla Venkat Rajam, Host induced gene silencing of vital pathogen gene for disease resistance
• Jawaharlal Nehru University, New Delhi, India, Junior Research Fellow, Dr. Neelima Mondal, To study transcriptional regulation of p53, p63 and p73 isoforms
• Dabur Oncology Division, Kaushambi, Delhi, India, Project Trainee, Dr. Manu Jaggi

• Selected to participate and present work at YIM2025 at Agra Courtyard mariott, March 2025.
• Best Teacher Award (2024) IAR Gandhinagar
• Selected to participate in EMBO laboratory leadership course held at IISER pune.
• Invited for a talk at “Women in Science” lecture series organized at IIT Gandhinagar, 2024.
• Invited to deliver a talk at IIT Chennai at Pan Cancer meet 2018.