Pawan D Patil
Ahmedabad
Summary
Dynamic and results-driven Senior Manager at Alentris Research Pvt Ltd with over 15 years of extensive experience in R&D, API and Impurity synthesis . Expertise includes managing diverse research projects from planning and execution to methodology application and documentation, ensuring successful presentation of findings. Proficient in process development for Novel Chemical Entities (NCEs) at both discovery and pilot levels, along with advanced purification techniques such as crystallization and flash chromatography. Strong leadership capabilities are demonstrated through effective project planning, time management, and team guidance, currently focusing on peptide synthesis initiatives while maintaining a commitment to EHS standards in laboratory environments.
Overview
15
15
years of professional experience
1
1
Certification
Work History
Senior Manager
Alentris Research Pvt Ltd
Gandhinagar
10.2023 - Current
- Company Overview: Contract Research Organization specializing in the synthesis of APIs, intermediates, nitrosamine impurities, and pharmacopoeial/in-house impurities.
- Currently managing peptide synthesis projects
- Design and execution of synthetic routes for pharmacopoeial, in-house, and process-related impurities of APIs and intermediates.
- Manage multiple projects simultaneously, ensuring they meet timelines, quality standards, and budget constraints.
- Conduct regular team meetings to review progress, troubleshoot issues, and assign responsibilities.
- Troubleshoot and optimize chemical reactions, scale-up processes, and purification techniques.
- Collaborate with analytical teams to interpret spectroscopic data for structural confirmation and purity profiling.
- Supervise and guide synthetic chemists in planning and executing multi-step organic synthesis.
- Provide technical guidance and mentorship to junior chemists, ensuring adherence to best laboratory practices and safety protocols.
- Ensure compliance with safety protocols and proper use of lab equipment.
- Prepare and review comprehensive experimental reports, technical documents, and regulatory submission data packages.
- Contract Research Organization specializing in the synthesis of APIs, intermediates, nitrosamine impurities, and pharmacopoeial/in-house impurities.
Group Leader
PharmACE Research Laboratory
Gandhinagar
07.2023 - 10.2023
- Company Overview: Research lab focusing on manufacturers of drug reference standards, working standards, impurity standards, metabolite standards and deuterated standards.
- Planned and optimized synthetic routes for target compounds and related impurities, ensuring efficiency and reproducibility.
- Conducted comprehensive literature reviews to evaluate and select viable synthetic pathways from established research.
- Research lab focusing on manufacturers of drug reference standards, working standards, impurity standards, metabolite standards and deuterated standards.
Scientist
Torrent Research Center
Gandhinagar
07.2014 - 06.2023
- Company Overview: A leading research center specializing in drug discovery.
- Responsible for the design, synthesis, and optimization of novel small molecules as potential drug candidates, in collaboration with multidisciplinary teams, to support discovery and preclinical development programs.
- Conduct literature surveys and patent searches to identify novel chemical space and avoid infringement.
- Managed and optimized chemical reactions, scaled-up processes, and purification techniques.
- Process Development for NCEs (Novel Chemical Entity) at Discovery Level up to pilot level.
- Mentored junior scientists, providing technical guidance and career development support.
- A leading research center specializing in drug discovery.
Research Associate
Piramal Discovery Solution (Formerly known as Oxygen Bioresearch)
Ahmedabad
10.2010 - 07.2014
- Company Overview: Integrated drug discovery Contract Research Organization (CRO).
- Perform multi-step organic synthesis, purification, and characterization of target compounds in a CRO environment; maintain accurate experimental records, ensure safety compliance, interpret analytical data, and contribute to timely project delivery in collaboration with cross-functional teams.
- Stay updated on modern synthetic methodologies and reaction techniques.
- Integrated drug discovery Contract Research Organization (CRO).
Education
Master of Pharmacy -
L.M. College of Pharmacy, Gujarat University
Ahmedabad, Gujarat, India07.2009
Bachelor of Pharmacy -
L.M. College of Pharmacy, Gujarat University
Ahmedabad, Gujarat, India04.2007
H.S.C -
Gyanbharti Vidhyalaya
Ankleshwar, Gujarat, India04.2003
S.S.C -
National High School
Ankleshwar, Gujarat, India04.2001
Skills
- Leadership and teamwork
- Project planning and management
- Literature search
- Analytical data interpretation
- Synthetic route design
- Mentorship and guidance
- Effective communication
Certification
- Registered Pharmacist, Registered Pharmacist of India by SPC
- IP Course Certification, Certified for the General Course of the Intellectual Property DL 101
Accomplishments
- Inventor – Patent, Honoured as Inventor – Patent for Benzothiazine Compounds as H3 Receptor Ligands (WO2013076590A1, 2013)
- Delivered Scientific Review, Presented review entitled as “DISCOVERY OF POTENT AND ORALLY BIOAVAILABLE DIHYDROPYRAZOLE GPR40 AGONISTS” at Torrent Research Centre in June 2018.
- Successful Drug Development, Successfully synthesized Selinexor (KPT-330) for Karyopharm Therapeutics, an Oral, Selective Inhibitor of Nuclear Export (SINE) Shows Anti-Prostate Cancer (PrCa) Activity Preclinically & Disease Control in Patients with Chemotherapy Refractory, Castrate-Resistant Prostate Cancer (CRPC)
Languages
Marathi
First Language
English
Advanced (C1)
C1
Gujarati
Advanced (C1)
C1
Hindi
Proficient (C2)
C2
Timeline
Senior Manager
Alentris Research Pvt Ltd
10.2023 - Current
Group Leader
PharmACE Research Laboratory
07.2023 - 10.2023
Scientist
Torrent Research Center
07.2014 - 06.2023
Research Associate
Piramal Discovery Solution (Formerly known as Oxygen Bioresearch)
10.2010 - 07.2014
Master of Pharmacy -
L.M. College of Pharmacy, Gujarat University
Bachelor of Pharmacy -
L.M. College of Pharmacy, Gujarat University
H.S.C -
Gyanbharti Vidhyalaya
S.S.C -
National High School
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