SHARADHA AYYAPAN

- Contributed to the Project management in pilot project mainly to coordinate with team, gain project requirements from customers, maintaining and updating PM artifacts in accordance with the QMS.
- Plan, Schedule, Coordinate the team members for the daily assigned tasks and monitor work by daily updates which are compliant to the applicable standards and guidelines.
- Provide oversight and approve protocol writing and finalization, documentation, research on vendor/supplier selection and ordering of materials and support a regulatory submission
- Assessed project milestones and team performance to keep staff on-task.
- Organized system operating procedures to strengthen controls and
Provided educational expertise and mentoring to junior team members.
- Gap assessment and IFU based on MDR for Gastrovideoscope and validation studies (Japan client).
- Complaint handling of medical devices based on regulatory compliance considering US FDA, 21 CFR Part 820.1820.198, ISO 13485:2016, also using a well-defined complaint handling process.
- Ensuring EU IVDR Regulation (22017/746) and risk management process as per 14971 for medical device.
- Evaluated and adopted new technologies to address changing industry needs.

- Isolated few potential microorganisms from the oil spill site and genetic modification of those organisms used for the bioremediation work
- Achieved growth of plants on those affected site soil with treating and mixing up with normal soil for about 60% of growth.
- Met with manager weekly to provide detailed project report and milestone updates.

- Analyzed project performance data to identify areas of improvement

- Reported regularly to managers on project budget, progress and technical problems.

- Created a database for all brain and neurologic receptors manually curated chemical database with all bioactive molecules with drug-like properties with all details and data abstracted from few other established databases
- Combining all primal details of a drug target to till date especially on the pharmacology aspect of the drug designing
- Complete analysis of the given target of the client’s interest and the possible ligands with greater potency and efficacy computationally
then experimenting with the scrutinized key drugs for their functional and binding assays.

- Conducted drug modeling, performance and integration testing.

- Instigated several government funding for our research projects especially in health care and molecular genetics by incorporating several cutting-edge technologies to perform assays to combat global challenges
- The Molecular diagnostics laboratory initiated for accreditation in accordance with legislative authorities, license for handling human samples, Occupational health and safety measures
- Identified several gene markers for human diseases especially on their specific targets to promote precision medicines for every individual analyzed based on qualitative and quantitative means using their genetic material (like DNA) obtained through body fluids and tissues (especially Report TAT is 48-72 hours)
- For procurement of molecular laboratory equipment, negotiated with the company dealer to reduce the costing up to 25-30% from its actual cost with an year extension for its maintenance and service period
- Maintaining complete record of the usage of chemicals using a software and the stocks of the consumables
- Engaged in few ayurvedic drugs for cancer studies in order to check the efficacy of the drug in selected cell lines which resulted in remarkable efficacy for selected drugs.
- Gathered, arranged, and corrected research data to create representative graphs and charts highlighting results for presentations.

- Involved in making the specified changes in the article only if it follows the designated journal style and technical and copy-editing part in the author S200 proof

- Also detailing the journal style if the author's correction deviates from the journal practice

- Technical editing done for more than 1000 articles with efficiency greater than 96% Had very less proof quality disapproval (PQD) of about less than 5% in the entire work period and qualified for appraisal within 8 months

- Reviewed articles for grammar, spelling, punctuation, syntax, accuracy, and compliance with quality standards.

- Supported publication by helping develop layouts and collaborating with production teams.

Title: Mutagenesis of Glugagon-like peptide-1 receptor (GLP-1R)