Summary
Overview
Work History
Education
Skills
relevant coursework
Interests
Certification
Involvement and Achievements
Timeline
Generic

Shreya Biju

PhD Applicant
THIRUVANANTHAPURAM

Summary

Dynamic cell biology researcher specializing in mitotic regulation, kinetochore–microtubule interactions, and protein biochemistry. Proficient in molecular cloning, mammalian cell culture, protein purification, immunoprecipitation, and confocal microscopy. Currently engaged in innovative research on Hec1–fibrous corona interactions utilizing engineered Ndc80 bonsai mutants in Prof. Tapas K. Manna’s laboratory at IISER Thiruvananthapuram. Committed to advancing knowledge through a PhD program focused on the molecular mechanisms governing chromosome segregation and ensuring mitotic fidelity.

Overview

3
3
years of professional experience
1
1
Certification

Work History

Studying kinetochore - microtubule interactions and Fibrous Corona regulation

IISER TVM
08.2025 - Current
  • Advisor: Prof. Tapas K. Manna
  • Investigated the role of the NDC80 complex (Hec1) and its interaction with Fibrous Corona proteins in regulating kinetochore-microtubule attachment. It involved studying MPS1-Hec1 interaction and its impact on recruitment of Fibrous corona proteins ROD1 and ZW10.
  • Requires expertise in cloning, mammalian cell culture, protein purification, transient transfection, agarose gel electrophoresis, SDS-PAGE, immunoprecipitation, and western blotting.

Protein Film Electrochemistry in BSA-doped Porphyrin Systems

IISER TVM
01.2025 - 05.2025
  • Advisor: Dr. Jerry A. Fereiro
  • Protein Film Electrochemistry is a technique used to study the redox chemistry of proteins. The investigated proteins are adsorbed as a sub-monolayer film on an electrode surface.
  • My project aimed to electrochemically characterize the BSA protein and its metalloporphyrin conjugates using PFE.

RNA sequencing and Pathway enrichment analysis

IISER TVM
06.2024 - 07.2024
  • Advisor: Dr. V. Stalin Raj
  • Internship under the guidance of Dr. V Stalin Raj.
  • Conducted RNA sequencing and pathway enrichment analysis using RStudio and functional bioinformatics tools.
  • Practiced essential molecular biology techniques, including plasmid DNA isolation, transformation, and immunoprecipitation.

Studying protein - protein interactions

IISER TVM
08.2023 - 11.2023
  • Advisor: Dr. Ramanathan Natesh
  • Investigated protein-protein and protein-ligand interactions using Ni-NTA affinity purification and biochemical assays.
  • Optimized purification yields and validated interaction specificity by SDS-PAGE and Western blot analysis.

Education

BS-MS Dual degree - Major in Biology, Minor in Chemistry

IISER TVM
India
05-2026

Higher Secondary education - Bio-Math

Chinthalaya Vidyalaya
Kerala
2021

High school education -

Christ Nagar Central School
Kerala
2019

Skills

  • Experimental: Mammalian cell culture, Transient transfection, Immunostaining, PCR cloning, Site-directed mutagenesis, SDS-PAGE, Western blotting, Bacterial cell culture, Agarose gel electrophoresis, Protein purification (GST pulldown assays)
  • Computational: RStudio, GraphPad Prism, ImageJ/Fiji, Microsoft Excel, basic command-line operations

relevant coursework

Cell Biology, Developmental Biology, Cell signaling, Advanced Virology,  Molecular Biology

Interests

Dance performer, Passionate about Music

Certification

Earned A+ certification in hands-on Immunology and Vaccine Technology under Dr. Surya Haritha S. Gained applied experience in antigen-antibody assays and immunoanalytical techniques.

Involvement and Achievements

  • Participated in the One-Week Workshop on Bacterial Communication and Pathogenesis, conducted by Prof. Dipshikha Chakravortty at IISER TVM from April 13 to April 21, 2026.
  • Participated in the Frontier Symposium in Biology held at IISER TVM from February 13 to February 15, 2026.
  • Participated in the One-Day Symposium on Biological Big Data Analysis held at IISER TVM on 7 November 2025.
  • Qualified for eligibility for Assistant Professor and PhD in the Joint CSIR-UGC NET JUNE 2025.
  • One among the Ishya’25 Tarang Winners, the annual Arts Fest at IISER TVM.
  • Awarded an A+ grade in the Training Program on the topic of Immunology at Rapture Biotech, Chennai, India (May 22-29, 2023), under the guidance of Dr. Surya Haritha S.
  • Received Certificate of Accomplishment as part of a science workshop on Vaccine Technology conducted by Haritha Institute and Research Foundation, Chennai, India (May 26-27, 2023).
  • Always an active member of the Science Fests and Cultural Fests at school and college.

Timeline

Studying kinetochore - microtubule interactions and Fibrous Corona regulation

IISER TVM
08.2025 - Current

Protein Film Electrochemistry in BSA-doped Porphyrin Systems

IISER TVM
01.2025 - 05.2025

RNA sequencing and Pathway enrichment analysis

IISER TVM
06.2024 - 07.2024

Studying protein - protein interactions

IISER TVM
08.2023 - 11.2023

BS-MS Dual degree - Major in Biology, Minor in Chemistry

IISER TVM

Higher Secondary education - Bio-Math

Chinthalaya Vidyalaya

High school education -

Christ Nagar Central School
Shreya BijuPhD Applicant