Summary
Overview
Work History
Education
Skills
Accomplishments
Research Summary
Future Research Interests
Teaching & Mentoring Experience
Disclaimer
Publications
Timeline
Generic
Chander Shekhar

Chander Shekhar

Research Scientist
Mumbai,MH

Summary

Accomplished Discipline Researcher with extensive academic R&D experience and a strong track record in Organic Synthesis. A self-motivated and dedicated professional known for an organized, systematic, and detail-oriented approach to research and problem-solving.

Overview

2
2
years of professional experience

Work History

Research Scientist

Macleods Pharmaceutical (India)
  • I have two years of Research Scientist experience in Macleods Pharmaceutical (India) R&D, specializing in the Oncology Department, with expertise in Synthetic Organic Chemistry.
  • Ph.D. THESIS (2018-2024): “Ring Closure Transformations: Concise Pathways to Access 6H-Benzo[c]chromenes, 9H-Fluorenes, Indeno[2,1-c]chromen-6(7H)-ones, Indene/Indane Esters, Indeno[a]indenones and Benzo[b]carbazoles” Supervisor: Prof. G. Satyanarayana (IIT Hyderabad, India).

Research Scientist

Macleods Pharmaceuticals
05.2024 - Current

Education

Doctor of Philosophy - Synthetic Organic Chemistry

Indian Institute of Technology Hyderabad
India
01-2024

M.Sc. - Chemistry, Organic Specialization

Kirori Mal College, Delhi University
Delhi
01-2017

B.Sc. Chemistry Hons. - undefined

Moti Lal Nehru College, Delhi University
Delhi
01-2015

Intermediate (12th Class) - undefined

Govt. Sr. Sec. School
Tiplat, Faridabad, Haryana
01-2012

Skills

Research and Experimental Techniques: Experience in Handling instruments like Microwave synthesizers (CEM), ElectraSyn (IKA), Heidolph& IKA rotatory evaporators, ATR (IR), Spectrophotometers, Chromatography (TLC and column chromatography) Familiar with NMR and HR-MS instruments

Technical Skills: I have expertise in synthetic chemistry, pioneering new C-C and C-X bond construction under transition metal catalysis and developing novel methodologies for synthesizing valuable carbocyclic and heterocyclic molecules and total synthesis of natural products I have the capability to carry out multi-step organic synthetic reactions (mg scale to gram scale) I have profound efficiency in handling air, moisture & light sensitive reactions

Accomplishments

  • CSIR-UGC National Eligibility Test (NET) in Chemical Science (Dec-2017): Qualified JRF(NET)-CSIR with 69 Rank.
  • Graduate Aptitude Test in Engineering (GATE) in Chemistry (2017) organized by IIT Roorkee: Qualified with Gate Score-341.
  • 3rd position (Certificate of Merit) in B.Sc. Chemistry, an annual function organized by Moti Lal Nehru College (DU) session 2014-2015.
  • 2nd position in “Quiz Competition”, an inter-school event organized by L&T DHANUSH during the academic year 2011-2012.

Research Summary

  • Palladium-Catalyzed Suzuki Coupling and NIS-Mediated Dehydrogenative Cyclo-etherification: A Concise Approach to 6,6-Disubstituted 6H-benzo[c]chromenes and Total Synthesis of Didehydroconicol.
  • Sequential One-Pot Process to Construct a Dual C–C Bond: Synthesis of Fluorenes and Total Synthesis of 4-O-Demethyl-nobilone.
  • Acid-Mediated Cascade Cyclization Pathway to Indeno[2,1-c]Chromen-6(7H)-Ones.
  • Acid-Mediated Domino-Cyclization of ortho-Formyl Cinnamate Esters: Synthesis of Substituted Indene/Indane Esters and Indeno[a]indenones.
  • Acid-Promoted Domino Access to Substituted Benzo[b]carbazoles.

Future Research Interests

  • I am very interested in working on organocatalysis, photocatalysis, electrocatalysis, and acid-mediated cyclization reactions for valuable organic transformations.
  • In addition, I am interested in researching innovative synthetic methodologies employing transition metal catalysis or metal-free reactions and applying these methodologies to the total synthesis of natural products, biologically active molecules, and molecules of material science interest.

Teaching & Mentoring Experience

  • Teaching Assistant for Postgraduate Organic Chemistry Practicals for one Semester (2019) in the Department of Chemistry at the Indian Institute of Technology Hyderabad, India.
  • Trained and mentored one master student on laboratory techniques and how to handle project work for their thesis, and partially mentored one master student on laboratory techniques and how to manage project work in the Department of Chemistry at the Indian Institute of Technology Hyderabad, India. Mr. Joydeep Roy (CY21MSCST11017), Thesis title: A Single-Column-Based Process Toward β-Naphthoate.
  • Trained and mentored one PhD student on laboratory techniques and how to handle project work in the Department of Chemistry at the Indian Institute of Technology Hyderabad, India.

Disclaimer

I hereby declare that all the above information is true and correct to the best of my knowledge.

Publications

  • Chander Shekhar and Gedu Satyanarayana
  • . Palladium-Catalyzed Suzuki Coupling and NIS-Mediated Dehydrogenative Cyclo-etherification: A Concise Approach to 6,6-Disubstituted 6H-benzo[c]chromenes and Total Synthesis of Didehydroconicol. Eur. J. Org. Chem. 2022, 2022 (18), e202101444. https://doi.org/10.1002/ejoc.202101444
  • . Sequential One-Pot Process to Construct a Dual C–C Bond: Synthesis of Fluorenes and Total Synthesis of 4-O-Demethyl-nobilone. Chemistryselect, 2023, 8 (26), e202302040. https://doi.org/10.1002/slct.202302040
  • . Acid-Mediated Cascade Cyclization Pathway to Indeno[2,1-c]Chromen-6(7H)-Ones. J. Org. Chem. 2023, 88, 19, 13404–13417. https://doi.org/10.1021/acs.joc.3c01459
  • . Acid-Mediated Domino-Cyclization of ortho-Formyl Cinnamate Esters: Synthesis of Substituted Indene/Indane Esters and Indeno[a]indenones. J. Org. Chem. 2024, 89, 7, 5069–5090. https://doi.org/10.1021/acs.joc.4c00301
  • . Acid-Promoted Domino Access to Substituted Benzo[b]carbazoles. J. Org. Chem. 2024, 89, 6, 3732–3746. https://doi.org/10.1021/acs.joc.3c02483
  • Dakoju Ravi Kishore, Chander Shekhar, and Gedu Satyanarayana
  • . Lewis Acid Mediated Domino Intramolecular Cyclization: Synthesis of Dihydrobenzo[f]Fluorenes. J. Org. Chem. 2021, 86 (13), 8706–8725. https://doi.org/10.1021/acs.joc.1c00525
  • Dakoju Ravi Kishore, Kishore, Komal Goel, Chander Shekhar, and Gedu Satyanarayana
  • . An Access to Benzo[a]Fluorenes, Benzo[b]Fluorenes, and Indenes Triggered by Simple Lewis Acid. J. Org. Chem. 2022, 87 (5), 2178–2203. https://doi.org/10.1021/acs.joc.1c02724
  • Chander Shekhar, Dakoju Ravi Kishore, and Gedu Satyanarayana
  • . Palladium Nanoparticles in C–H Functionalization Reactions. (Book Chapter) https://doi.org/10.1002/9783527834242.chf0008
  • Poster Presentation on “Palladium-Catalyzed Suzuki Coupling and NIS-Mediated Dehydrogenative Cyclo-etherification: A Concise Approach to 6,6-Disubstituted 6H-benzo[c]chromenes and Total Synthesis of Didehydroconicol” at 27th ISCBC International Conference (ISCBC-2022, Research and Innovation in Chemical, Pharmaceutical and Biological Sciences), Birla Institute of Technology, Mesra, Ranchi (Nov-2022), India.
  • Online Presentation on “Palladium-Catalyzed Suzuki Coupling and NIS-Mediated Dehydrogenative Cyclo-etherification: A Concise Approach to 6,6-Disubstituted 6H-benzo[c]chromenes and Total Synthesis of Didehydroconicol” at the annual Chemistry In-House Symposium (April2021), Indian Institute of Technology, Hyderabad, India.
  • Attended a workshop on “Master the Publishing Process” at IIT Hyderabad, conducted by ACS at IIT Hyderabad (July 2022), India.

Timeline

Research Scientist

Macleods Pharmaceuticals
05.2024 - Current

Intermediate (12th Class) - undefined

Govt. Sr. Sec. School

B.Sc. Chemistry Hons. - undefined

Moti Lal Nehru College, Delhi University

M.Sc. - Chemistry, Organic Specialization

Kirori Mal College, Delhi University

Doctor of Philosophy - Synthetic Organic Chemistry

Indian Institute of Technology Hyderabad

Research Scientist

Macleods Pharmaceutical (India)
Chander ShekharResearch Scientist