Devanshu Srivastava
11 years of Experience in Biopharma
Lucknow
Summary
- Aim to penetrate and learn all realms of Life science dept. and take it to new height.
- Interested in taking new opportunities for technical growth
- Good communication and interpersonal skills
- Strong leader and problem-solver dedicated to streamlining operations to decrease costs and promote organizational efficiency. Uses independent decision-making skills and sound judgment to positively impact company success.
Overview
11
11
years of professional experience
Work History
Associate Scientific Manger
Biocon
08.2022 - Current
- Developed and implemented continuous chromatography approach in large scale and small system
- Evaluated membrane chromatography to replace traditional resin platforms
- Improved employee retention by providing ongoing professional development opportunities and fostering a supportive work environment.
- Conducted employee performance reviews, setting attainable objectives aligned with company priorities and offering constructive feedback for continuous improvement.
- Collaborated closely with regulatory authorities throughout the product development process ensuring compliance adherence and expedited approval timelines.
- Increased project success rates through effective team management and timely communication with stakeholders.
- Evaluated emerging technologies'' potential benefits for organizational goals; strategically incorporated these tools into existing workflows as appropriate.
Assistant Manager
CurateQ Biologics
11.2020
- Responsible for downstream processing in MSAT, including process descriptions, technology transfer, scale up, cleaning verification, and validation
- Collaborated with cross-functional departments for process deviation investigation and closure
- Conducted structured data analysis and trend identification
- Worked closely with process development, analytical, and manufacturing teams.
Associate Scientist
Syngene International
02.2018 - 10.2020
- Developed purification protocols for different proteins and antibodies in mammalian systems
- Troubleshot challenging proteins for purity
- Designed final buffers for protein stability
- Worked on early stage development of novel molecules
- Worked with various tagged and non-tagged antibodies/proteins.
Senior Officer
Premas Biotech Pvt Ltd
12.2013 - 02.2018
- Handled chromatographic systems and purification of proteins from soluble and IB's preparation
- Worked with mammalian, bacterial, and natural sources for protein purification.
Education
INT.M.Tech (Biotechnology) -
Meerut university (C.C.S.U)
Class XII (CBSE Board) - undefined
R.L.B sec-14 Indra nagar Lucknow.
Class X (CBSE Board) - undefined
R.L.B sec-14 Indra nagar Lucknow.
Skills
Continuous chromatography implementation
Evaluation of new technologies such as membrane chromatography
Cost Reduction
Team motivation
Strategic Planning
Excellent Communication
Team Development
Task Prioritization
Accomplishments
- Won the best Award for Achievers at Biocon Biologics Ltd for successfully scale-up of the molecule 2022-2023
- Won the best Award for Rising star of the year at Premas Biotech Pvt Ltd 2017-2018
- Won the best Award for CALL BEYOND DUTY at Premas Biotech Pvt Ltd 2016-2017
- News Letter published by Premas Biotech Pvt Ltd on "Plant Protein Purification Process optimization".
- Delivered more than 200 kg's of protein
- Done 1000 plus runs on Akta Purifier, Akta Pilot and Biological duo flow independently.
- Participated in National conference in BITS PILANI 2011
- Written a Review article which was published during conference 2010
- Have participated in various sports and athletic events and won prizes in school and college
Other Information
Dr. Ajay Kumar Srivastava, Indian, Married, Making Friends, Playing Cricket, Football and Listening Songs., English, House No. 6, Tulsi Vihar Colony, Indira Nagar, Lucknow, 226015
Industrialprojects
- Purification Peg-GCSF, GCSF, Trastuzumab, Pembrolizumab and other mammalian projects.
- Involved in Scale UP and Tech Transfer of microbial and mammalian projects with all CPPs, KPPs, Purification of IGFR 1, Human, Mouse and Rat antibody and other reagent's proteins.
- Develop the protocol for the purification of this tagged protein and maintain the purity with 90%
- Purification of enzyme inhibitors for oral vaccine.
- Process development and optimization at small scale and then taken to pilot scale for large scale purification. Maintain the purity more than 85% and stability of the product.
- Purification of a recombinant carrier protein for diphtheria toxin
- Part of the team in process development and optimization in purification at lab scale and pilot scale purification. Developed the protocol for folding and refolding of insoluble protein.
- Purification of recombinant enzyme for synthesis of branched-chain amino acids
- Process development and optimization at small scale and then taken to pilot scale for large scale purification. Maintain the purity more than 75% and stability of the product
Projects
Preliminary Characterization of Bacteriophage Encoded Hyaluronidase 'HylP2' from Streptococcus pyogenes, 07/04/2012, 11/04/2012, This project was done at CDRI Lucknow under Dr Sohail Akhtar. In this project cloning, expression and purification was performed and then folding of protein with help of senior fellows at the lab. Purified the hylp protein from streptococcus and done biophysical characterization of the protein. Biosynthesis of Nanoparticles using grape callus cells and their effect on the growth of cells, 02/11/2013, 07/30/2013, This project was done at National Chemical Laboratory, Pune under Dr. Urmil. J. Mehta. Synthesize silver and gold nanoparticle from grape callus cells with help of silver nitrate and gold chloride solution and analyze the effect of silver particle on growth of cells
Timeline
Associate Scientific Manger
Biocon
08.2022 - Current
Assistant Manager
CurateQ Biologics
11.2020
Associate Scientist
Syngene International
02.2018 - 10.2020
Senior Officer
Premas Biotech Pvt Ltd
12.2013 - 02.2018
INT.M.Tech (Biotechnology) -
Meerut university (C.C.S.U)
Class XII (CBSE Board) - undefined
R.L.B sec-14 Indra nagar Lucknow.
Class X (CBSE Board) - undefined
R.L.B sec-14 Indra nagar Lucknow.
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